Clinical trials: Exercise Physiology
Endothelial Function (Reactive Hyperemia)
MOVING - MOtiVation, INtervention and Vascular chanGe
Background: The impact of demographic changes on workplace has increased the importance of effective occupational preventive health programs.
- Trial name
- MOVING (NCT01919632)
- Testing
- health-behavior seminar and endurance exercise
- Where
- 2 sites in Germany
- Volunteers
- 330 people
- Sponsor
- Technical University of Munich
Physical Activity, Mental Health Wellness 1
Physical Exercise for Education ('Fit to Study')
Neuroscience evidence suggests that physical exercise can influence brain function and structure, both immediately and in the long-term.
- Conditions
- Physical Activity, Mental Health Wellness 1, Cognitive Function 1, Social, Academic Attainment
- Trial name
- FTS (NCT03286725)
- Testing
- Physical Education (PE) Programme
- Where
- United Kingdom
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Hearing Impaired Children
Effects of Pilates and Balance Proprioception Exercises on Hearing Impairment
Static balance is the ability to hold the body in a specific position and posture, while dynamic balance is the ability to maintain balance while moving.
- Trial name
- NCT06198049
- Testing
- Pilates Training, Balance Proprioception Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Respiratory Function Tests
Exercise Induced Asthma and Airway Reactivity in Athletes
The overall aim is to explore pathophysiological factors related to airway hyperresponsiveness to direct and indirect provocation stimuli in athletes with different sport activities, with special focus on epithelial reaction…
- Trial name
- NCT00798564
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Cerebral Palsy, Respiratory Function
Inspiratory Muscle Training in Children With Cerebral Palsy: Effects on Respiratory and Motor Functions
This study investigates the effect of inspiratory muscle training on respiratory parameters, trunk control, upper extremity function and swallowing in patients with cerebral palsy aged 5-18 years.
- Conditions
- Cerebral Palsy, Respiratory Function, Balance, Swallowing
- Trial name
- NCT07041593
- Testing
- Inspiratory muscle training and standard neurodevelopmental physiotherapy (SNP), Standard neurodevelopmental physiotherapy (SNP)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Sadık Emre ÇELEBİ
Premature Birth
Preterm Lung Function and Exercise Response Measured by OEP
This study will explore lung function and respiratory health in school-aged children who were born prematurely at <32 weeks gestation.
- Trial name
- NCT04239287
- Testing
- Lung function + exercise tests
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Chronic Lung Disease, Chronic Obstructive Pulmonary Disease
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with…
- Conditions
- Chronic Lung Disease, Chronic Obstructive Pulmonary Disease, Acute Lymphoblastic Leukemia, Heart Transplant
- Trial name
- FLASHLITE (NCT05025774)
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Peripheral Vascular Disease
Physical Activity, Function and Quality of Life in Patients After Endovascular Treatment
The purpose of this study is to investigate how systematic physical training after endovascular treatment influence the durability of the endovascular treatment and how it effects physical function, quality of life and future…
- Trial name
- NCT01109732
- Testing
- Systematic physical training with instructor
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Spastic Cerebral Palsy
Efficacy of Physical Fitness Training Combined With Exercise Therapy on Gait in Children With Cerebral Palsy
This observational study is designed to investigate the time-dynamic characteristics of gait variability in children with spastic cerebral palsy (SCP).
- Trial name
- NCT07316985
- Testing
- 3-Minute Walking Gait and Surface Electromyography Assessment
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LiNa Zhang
Cystic Fibrosis, Muscle Strength
Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients
This study was designed to investigate the relationship between upper extremity muscle strength and endurance, functional capacity, and quality of life child and adolescent with cystic fibrosis
- Conditions
- Cystic Fibrosis, Muscle Strength, Pulmonary Function, Functional Capacity
- Trial name
- NCT04734743
- Testing
- cystic fibrosis
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cagtay Maden
Pediatric Inflammatory Bowel Diseases, Pediatric Crohns Disease
Exercise Training in Youth With Inflammatory Bowel Disease
Children and adolescents with inflammatory bowel disease (IBD) suffer from many extra-intestinal side effects, including impaired muscle strength, low aerobic fitness, low bone density, and chronic inflammation.
- Conditions
- Pediatric Inflammatory Bowel Diseases, Pediatric Crohns Disease, Pediatric Ulcerative Colitis
- Trial name
- NCT05591976
- Testing
- Exercise training program
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- McMaster University
Physical Disability
Use of Adapted Controllers for Active Video Gaming in People With Physical Disabilities
The purpose of this study is to compare the effectiveness of off-the-shelf (OTS) and adapted game controllers on quality of game play, enjoyment, and energy expenditure during active video gaming in persons with mobility…
- Trial name
- NCT02994199
- Testing
- Active video gaming
- Volunteers
- 105 people
- Sponsor
- University of Alabama at Birmingham
Congenital Heart Disease, Single Ventricle
Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training
Introduction: The Fontan operation is the surgical treatment in most patients with either anatomic or functional single ventricles.
- Conditions
- Congenital Heart Disease, Single Ventricle, Univentricular Heart
- Trial name
- NCT02283255
- Testing
- Aerobic Exercise Training, Inspiratory Muscle Training, No Exercise Training
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Venous Thrombosis Deep (Limbs), Post Thrombotic Syndrome
EXERT: Exercise Physiology After Thrombosis
Deep vein thrombosis (DVT) can cause long-term scarring and narrowing of veins. When there is extensive damage to the veins in the legs, groin or abdomen it can affect the way that blood is able to flow back up to the heart.
- Trial name
- NCT05296499
- Testing
- Cardiopulmonary exercise test (CPET), Exercise cardiac MRI, 6 minute walk test
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Spina Bifida
Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida
This study will investigate whether adding motor imagery to thoracic expansion exercises can improve respiratory function in children with spina bifida.
- Trial name
- NCT07846202
- Testing
- Thoracic Expansion Exercises, Motor Imagery-Supported Thoracic Expansion Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Recurrent Prostate Cancer, Stage IV Prostate Cancer
Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy
This randomized pilot clinical trial studies intensive diet and exercise or standard of care in improving physical function and quality of life in patients with prostate cancer undergoing androgen deprivation therapy.
- Trial name
- IDEA-P (NCT02050906)
- Testing
- behavioral dietary intervention, exercise intervention, behavioral activity counseling
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Obesity & Overweight
Effects of Exercise on Lipids and Endothelial Function in Youth
This study is for individuals who have a BMI that is at or above the 95th percentile and are participating in the Cincinnati Children's Hospital Healthworks! Structured weight loss program.
- Trial name
- NCT07409064
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cardiometabolic Risk, Executive Function
Effects of Diet and Exercise Interventions on Cardiometabolic Risk Markers, Executive Function, and Intestinal Flora
The purpose of this study is to estimate the effects of diet and exercise interventions on body weight, cardiovascular metabolic markers, executive function, and intestinal flora among undergraduate students, as well as the…
- Conditions
- Cardiometabolic Risk, Executive Function, Intestinal Microbiome
- Trial name
- NCT04834687
- Testing
- Exercise, Diet
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University