Clinical trials: Exercise Sensitivity
Metabolism Disorder, Insulin Sensitivity
Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile
Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children.
- Conditions
- Metabolism Disorder, Insulin Sensitivity, Obesity, Pediatric
- Trial name
- NCT03003754
- Testing
- High Intensity Training (HIT) + Resistance Training (RT), Control group
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Obesity and Type 2 Diabetes
Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth
The overall goal of this project is to examine the physiological and metabolic effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral component utilizing motivational…
- Trial name
- NCT00693511
- Testing
- Circuit Training, Circuit training + motivational interviewing
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Exercise Induced Asthma, House Dust Mite Allergy
Epigenetic Regulation of Exercise Induced Asthma
The purpose of this study is to investigate the micro ribonucleic acid (mRNA) profiles of patients with EIA without allergic sensitization and EIA with house dust mite sensitization compared to that of healthy controls.
- Trial name
- NCT05174689
- Testing
- Exercise challenge in the cold chamber (ECC), mRNA profile, standard diagnostic
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Sickle Cell Disease
Sickle Cell Pro-Inflammatory Response to Interval Training Study
Recommendations for exercise prescription currently do not exist for individuals with sickle cell anemia (SCA) despite the known impact that SCA-related complications has on physical functioning and fitness.
- Trial name
- SPRINTS (NCT03653676)
- Testing
- Exercise Test (CIIT)
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Bronchospasm, Exercise-Induced
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA.
- Trial name
- STAMINA (NCT01691079)
- Testing
- ipratropium bromide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity, Type 2 Diabetes Prevention
The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children
The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight…
- Conditions
- Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
- Trial name
- NCT00108901
- Testing
- Aerobic exercise program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Exercise, Obesity
Glucose and Lipid Metabolism in Adolescents
A 12 wk aerobic exercise program will reduce visceral, hepatic and intramyocellular fat accumulation and improve insulin sensitivity and glucose metabolism in obese sedentary Hispanic adolescents.
- Conditions
- Exercise, Obesity, Insulin Sensitivity
- Trial name
- NCT00998855
- Testing
- Exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Sarcoidosis
Muscle Strength and Exercise Capacity in Sarcoidosis Patients
The aim of this study is to examine exercise capacity, muscle strength and fatigue in sarcoidosis. In this longitudinal study the changes in prevalence of exercise intolerance, reduced muscle strength and fatigue will be…
- Trial name
- NCT00854672
- Where
- Netherlands
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Metabolism, Physical Fitness
High Intensity Interval Versus Continuous Moderate Intensity Training: Maximizing the Benefits of Exercise in Overweight Adolescents
6-week, single site, two parallel arm, randomized, controlled trial comparing the effectiveness of a High Intensity Interval Training (HIIT) versus a continuous Moderate Intensity Training (MIT) program on cardiovascular and…
- Trial name
- HIIT-MAX (NCT01935323)
- Testing
- High Intensity Interval Training, Moderate Intensity Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Type 2 Diabetes Mellitus, Adolescent Obesity
A Study of the Effects of Exercise Intensity on Insulin Sensitivity in Overweight Youth
Background: The investigators know that exercise helps children develop strong bones and muscles and generally stay healthy. What is unclear however, is how much exercise a child needs to lower their risk of developing type 2…
- Trial name
- POWER (NCT00755547)
- Testing
- Aerobic Exercise Training
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Prehypertension, Blood Pressure
The Effects of a Jump Rope Exercise Program on Body Composition and Self-efficacy in Obese Adolescent Girls
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on body composition, blood pressure, insulin resistance, and academic self-efficacy in prehypertensive adolescent obese girls.
- Conditions
- Prehypertension, Blood Pressure, Abdominal Obesity, Self Efficacy
- Trial name
- NCT03898518
- Testing
- 12-week jump rope exercise program
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Asthma in Children, Obesity, Childhood
Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity
Guidelines from the American Thoracic Society strongly recommend interval warm-up exercise before planned exercise to reduce exercise-induced bronchoconstriction severity.
- Conditions
- Asthma in Children, Obesity, Childhood, Exercise Induced Bronchospasm
- Trial name
- NCT03586544
- Testing
- Albuterol Sulfate, Interval Warm-up exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Exercise Induced Bronchospasm, Athletes
Diagnosis of EIB in Young Elite Athletes (13-18 y)
The investigators recently observed airway inflammation and increased damage-associated molecular pattern (DAMP) level in sputum of children (age 11-12y) and adolescents (18-23y) from elite sport programs in Belgium with…
- Conditions
- Exercise Induced Bronchospasm, Athletes, Adolescent
- Trial name
- NCT03587675
- Testing
- EVH test
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Exercise Induced Asthma
Study of Airway Inflammation in Relation to Exercise in Elite Athletes
High school elite training programs are today more and more under development in several 'elite sport schools' in Belgium, in order to select and train future elite athletes already at young age.
- Trial name
- NCT01942096
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma
Exploring the Effects of Sleep Patterns and Physical Activity on Asthma in Adolescents With Wrist-worn Smart Devices
This is a research study to find associations between asthma symptoms and sleep patterns and physical activity among adolescent patients with persistent asthma.
- Trial name
- NCT02556567
- Testing
- Fitbit® Charge Heart Rate (HR) wristband
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Exercise Induced Asthma, Exercise Induced Bronchospasm
Evaluation of Exercise Induced Bronchoconstriction Using a Novel Automated Digital Clinical Decision System
The primary objective of this study is to assess if the unstandardized field exercise challenge test (ECT) using AsthmaTuner can be performed independently by youths that have been investigated for asthma.
- Conditions
- Exercise Induced Asthma, Exercise Induced Bronchospasm, Pediatric Respiratory Diseases
- Trial name
- NCT05162703
- Testing
- AsthmaTuner
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Adolescent Behavior, Asthma
Breathing Retraining for Asthma Trial of Home Exercises for Teenagers
This trial will address the impaired quality of life of young people with asthma, despite appropriate medicines. Research shows that young people report needing to calm themselves down during an asthma attack to control their…
- Trial name
- Breathe4T (NCT05006703)
- Testing
- Breathe for Teens (Breathe4T)
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Southampton