Clinical trials: Extremity Fracture Lower
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Fracture of Lower Limb
Effects of Rhythmic Auditory Stimulation on Range of Motion in Post- Fracture Rehabilitation of Lower Limb
This study aims to investigate the effects of rhythmic auditory stimulation on pain levels and range of motion in children undergoing post-fracture rehabilitation of the lower limb.
- Trial name
- NCT07579520
- Testing
- Rhythmic Auditory Stimulation (RAS)
- Where
- Pakistan
- Volunteers
- 17 people
- Sponsor
- Riphah International University
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Deep Vein Thrombosis, Pulmonary Embolism
The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial
It is known that patients who fracture their legs sometimes develop blood clots (known as deep vein thrombosis) in their legs. These clots may cause pain and swelling in the leg or they may detach and travel to the lungs…
- Trial name
- NCT00187408
- Testing
- Low Molecular Weight Heparin (dalteparin)
- Where
- 13 sites in Canada
- Volunteers
- 700 people
- Sponsor
- Sunnybrook Health Sciences Centre
Femoral Fractures, Tibial Fractures
Depuy Synthes Lower Extremity Shaft Nail Registry
The purpose of this post-market registry is to monitor the clinical safety and performance (union rates and time to union) of two DePuy Synthes lower extremity shaft nails: RFN-Advanced Retrograde Femoral Nailing System (RFNA)…
- Trial name
- NCT05272631
- Testing
- Retrograde Femoral Nail Advanced, Tibial Nail Advanced
- Where
- 8 sites in United States
- Volunteers
- 241 people
- Sponsor
- DePuy Synthes Products, Inc.
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic
Deformity, Defect, Congenital
Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Orthofix Srl put the JPS on the European market (2019) by the mean of a pre-market clinical evaluation made under the Medical Device Directive (MDD) requirements that were based on the analysis of the scientific literature of…
- Conditions
- Deformity, Defect, Congenital, Trauma
- Trial name
- JPS (NCT05245617)
- Testing
- JuniOrtho™ Plating System™
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Orthofix s.r.l.
Procedural Sedation
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Abstract Background: Ketamine has been introduced as one of the most common drugs, administered to sedate children for different painful procedures in the emergency department (ED) but administration in higher dosage causes some…
- Trial name
- NCT03499886
- Testing
- Ketamine Hydrochloride 50Mg/1mL Solution for Injection, Ketamine Hcl 50Mg/Ml Inj
- Where
- 2 sites in Iran
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Stress Fracture Foot, Stress Fracture Ankle
Detecting and Assessing Leg and Foot Stress Fractures Using Photon Counting CT
Stress fractures (fatigue or insufficiency fracture) are caused by the mismatch between bone strength and chronic stress applied to the bone. The vast majority of these fractures occur in the lower extremity.
- Conditions
- Stress Fracture Foot, Stress Fracture Ankle, Stress Fracture of Tibia, Stress Fracture Metatarsal
- Trial name
- FootPCCT (NCT06024798)
- Testing
- Photon-Counting-Computed-Tomography
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Balgrist University Hospital
Femur Fracture
Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture
The goal of this prospective observational study is to compare pain control strategies in children with femur fractures. Researchers will compare ultrasound-guided fascia iliaca compartment nerve block to IV pain control alone.
- Trial name
- PLEXUS (NCT05947292)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Nerve Block
- Where
- 10 sites in United States, Australia
- Volunteers
- 114 people
- Sponsor
- Zachary Binder
Ceserean Section, Lower Limb Fractures
Infection Prevention for "Bellwether" Surgery in Ethiopia
The study examines surgical site infections and antimicrobial resistance following life-saving surgeries like C-sections and leg fracture repairs in Ethiopia.
- Conditions
- Ceserean Section, Lower Limb Fractures, Surgical Site Infection (SSI)
- Trial name
- NCT07647796
- Testing
- Surgical Site Infection Prevention and Control (IPC) Bundle
- Where
- Ethiopia
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Pediatric Fractures, Lower Extremity Fractures
Loss of Parental Workforce in Paediatric Fractures
Childhood fractures are frequently encountered in orthopaedic practice. 40-64% of boys and 25-40% of girls have at least one fracture by the age of 16.
- Conditions
- Pediatric Fractures, Lower Extremity Fractures, Upper Extremity Fractures
- Trial name
- NCT06891027
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Lower Extremity Fracture
Feasibility and Efficacy of the Use of Telephysiotherapy in Anantapur
Injuries remain the most frequent cause of mortality in children and young people. Studies with: telephysiotherapy programmes have published results of effectiveness, validity, non-inferiority and important advantages, providing…
- Trial name
- Telefisio (NCT04946695)
- Testing
- Telefisio India
- Volunteers
- 30 people
- Sponsor
- University of Malaga
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Metatarsal Stress Fracture, Stress Fracture of Tibia
Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting
The goal of this clinical trial is to compare photobiomodulation therapy (PBMT) in addition to standard of care in the treatment of tibial and metatarsal bone stress injuries in a military training setting.
- Trial name
- PM12 (NCT05843864)
- Testing
- Photobiomodulation Therapy with Standard Physical Therapy
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Brooke Army Medical Center
Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb
Screw Lengths in Radius Volar Plates
Background Fractures of the distal radius are among the most common. Major complications, including irritation and rupture of the extensor tendons, may occur if epiphyseal screws of inappropriate length are used.
- Conditions
- Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb, Fracture Fixation, Internal
- Trial name
- PESLDRF (NCT03634865)
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Brest
Compartment Syndrome Traumatic Lower Extremity, Compartment Syndrome Traumatic Upper Extremity
Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
Compartment syndrome remains a very serious complication of lower extremity trauma and/or procedural cases that involved lower or upper extremity surgery.
- Trial name
- NCT04012723
- Testing
- MY01 Continuous Compartmental Pressure Monitor
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- MY01 Inc.
Stress Fracture, Ultrasound Therapy
Comparison of Ultrasound and X-ray as Screening Tests for Diagnosis of Lower Extremity Stress Fracture.
Hypothesis: Diagnostic ultrasound is an appropriate screening test for acute stress fracture in the lower extremity and is superior to x-ray.
- Conditions
- Stress Fracture, Ultrasound Therapy, Musculoskeletal Ultrasound
- Trial name
- NCT03116360
- Testing
- Diagnostic Ultrasound
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Chronic Postsurgical Pain
CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures
The purpose of this study is to assess the proteomics and transcriptomic differences between pain-free control subjects and patients with chronic postoperative pain through single-cell sequencing technology.
- Trial name
- NCT06126289
- Volunteers
- 20 people
- Sponsor
- Xuzhou Central Hospital