Clinical trials: Eye Disease
Trauma, Psychological, Stress, Psychological
EMDR Therapy in Young Children, a Double-blinded Randomized Controlled Trial
This project aims to answer to the question of EMDR effectiveness in young children and to determine whether or not the therapy effectiveness is related to the level of cognitive functioning in young children.
- Conditions
- Trauma, Psychological, Stress, Psychological, Anxiety Disorders
- Trial name
- EMDRJEER (NCT05419934)
- Testing
- EMDR therapy, CBT Control therapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Lenval
Dry Eye Syndromes
Comparison Of Blue Light Filter Feature and Blue Blocking Lenses in Digital Device Users With Dry Eye Patients
Comparing Blue Light Filter feature and Blue Blocking Lenses for Dry Eye Patients Prolonged screen time can exacerbate dry eye symptoms.
- Trial name
- NCT06913504
- Testing
- Blue cut filter, blue cut glasses
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Superior University
Iron Deficiency, Iron-deficiency Anemia
Non-invasive Optical Detection of Iron Deficiency in Children
This study aims to evaluate a prototype device detecting zinc protoporphyrin-IX fluorescence non-invasively from the intact oral mucosa in children.
- Conditions
- Iron Deficiency, Iron-deficiency Anemia, Child
- Trial name
- IronKids (NCT02701309)
- Testing
- Non-invasive Iron detection device via Zinc-Protoporphyrin
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Thyrotoxicosis, Peak Systolic Velocity of Superior Thyroid Artery
Differential Diagnosis of STA-PSV in Thyrotoxicosis
Aim: Graves's disease and thyroiditis can both characterized with thyrotoxicosis, but their clinical outcome and therapy is quiet different.
- Conditions
- Thyrotoxicosis, Peak Systolic Velocity of Superior Thyroid Artery, Thyroiditis, Graves Disease
- Trial name
- NCT01227499
- Where
- China
- Volunteers
- 169 people
- Sponsor
- xiaolong zhao
Amblyopia
Disinvestment Study of Population-Based Vision Screening in Children
The purpose of this study is to determine the optimal screening intervals and cost-effectiveness of population-based vision screening in preverbal children in the Netherlands.
- Trial name
- NCT01675193
- Testing
- Disinvestment protocol
- Where
- 2 sites in Netherlands
- Volunteers
- 10,803 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Esotropia
A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD
Childhood esotropia (ET) is a common cause of visual disability, and its early management is critical for optimal visual and developmental outcomes.
- Trial name
- ETS4 (NCT07470164)
- Testing
- Botulinum toxin A, bilateral medial rectus recession
- Volunteers
- 244 people
- Sponsor
- Jaeb Center for Health Research
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ophthalmia Neonatorum
Prevalence of Conjunctivitis and Indentification of Risk Factors With and Without Prophylactic Antibiotic Treatment in Neonates
The French guidelines for the use of Rifamycine eye drops in delivery room to prevent neonatal conjunctivitis have been actualized.
- Trial name
- CRY-NOT (NCT03528915)
- Testing
- Rifamycine treatment, whithout Rifamycine treatment
- Where
- France
- Volunteers
- 881 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cleft Palate
Optic Nerve Sheath Diameter in Patients Undergoing Palatoplasty
The purpose of this study is to evaluate the change of the optic nerve sheath diameter according to the change of the neck position in pediatric patients undergoing palatoplasty.
- Trial name
- NCT03585608
- Testing
- Neck extension
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Axial Myopia, Refractive Errors
Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure
The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye…
- Trial name
- NCT03552016
- Testing
- Oral Riboflavin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Refractive Error
First-Sight Refractive Error Correction: Direct Comparison to Autorefraction Results in Children 7 to 18 Years of Age
Proof of concept study to compare the best corrected visual acuity obtained via First-Sight lenses with the autorefraction in children.
- Trial name
- NCT01365884
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Myopia
Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
The purpose of this study was to compare a new daily disposable, silicone hydrogel contact lens to marketed daily disposable, silicone hydrogel contact lenses.
- Trial name
- TUNGSTEN (NCT01371552)
- Testing
- delefilcon A contact lens, filcon II 3 contact lenses, narafilcon A contact lenses
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- CIBA VISION
Cytomegalovirus Retinitis, HIV Infections
An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access
To provide oral ganciclovir to patients who require maintenance for control of cytomegalovirus (CMV) retinitis, but who lack patent permanent central venous access for long-term administration of intravenous drugs.
- Trial name
- NCT00002135
- Testing
- Ganciclovir
- Where
- United States
- Sponsor
- Hoffmann-La Roche
Endophthalmitis, Eye Infections
Endophthalmitis Vitrectomy Study (EVS)
To determine the role of initial pars plana vitrectomy in the management of postoperative bacterial endophthalmitis. To determine the role of intravenous antibiotics in the management of bacterial endophthalmitis.
- Trial name
- NCT00000130
- Testing
- Intravitreal Antibiotics, Initial Pars Plana Vitrectomy
- Sponsor
- National Eye Institute (NEI)
Strabismus, Exotropia
Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus
The current measurement methods of strabismus include the corneal light reflection method, prism alternate covering, etc., which especially rely on the subjective experience of doctors, and there is a large error between…
- Conditions
- Strabismus, Exotropia, Esotropia, Vertical Strabismus
- Trial name
- NCT05615519
- Testing
- A new technology based on 3D reconstruction and deep learning algorithm to achieve an automatic diagnosis of strabismus based on patient-sourced videos of programmatic cover tests.
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pediatric Glaucoma, Elevated IOP in Pediatric Patients
Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients
The purpose of this study is to evaluate the intraocular pressure (IOP)-lowering efficacy of Travoprost 0.004% POLYQUAD (PQ) ophthalmic solution compared to Timolol ophthalmic solution (0.5% or 0.25%) in pediatric glaucoma…
- Conditions
- Pediatric Glaucoma, Elevated IOP in Pediatric Patients, Ocular Hypertension in Pediatric Patients
- Trial name
- NCT01652664
- Testing
- Travoprost 0.004% PQ ophthalmic solution, Timolol, 0.5% or 0.25% ophthalmic solution, Travoprost Vehicle
- Volunteers
- 184 people
- Sponsor
- Alcon Research
Pseudophakic Bullous Keratopathy, Fuchs' Endothelial Dystrophy
Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEK
To evaluate the clinical outcomes (pos toperative best corrected visual acuity, endothelial count) and anatomical results (interface smoothness) of DSAEK with Femto LDV-prepared grafts from the endothelial side.
- Trial name
- NCT06652321
- Testing
- Endothelial Side Up Femtosecond Laser Assisted DSAEK
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Dar El Oyoun Hospital
Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB)
Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa
This study consists of two phases: an Observational Phase to evaluate the natural history of ocular manifestations in subjects with Dystrophic and Junctional Epidermolysis Bullosa, followed by a Treatment Phase to assess the…
- Conditions
- Junctional Epidermolysis Bullosa, Epidermolysis Bullosa (EB), Dystrophic Epidermolysis Bullosa, Recessive Dystrophic Epidermolysis Bullosa
- Trial name
- GOTAS-ELK-EB (NCT06713434)
- Testing
- ELK-003 (Standarized Amniotic Fluid Secretome Eye Drops)
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Fundación DEBRA Chile, Niños Piel de Cristal
Esotropia
Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at Near
Compare the proportion of BFL and SVL participants with treatment failure by 36 months, compare binocular function test scores between the BFL and SVL groups with both groups in BFL at 38 months after randomization (or 2 months…
- Trial name
- ETS3 (NCT05527015)
- Testing
- Bifocal Spectacles, Single Vision Lenses
- Sponsor
- Jaeb Center for Health Research
Myopia
Exploratory Study on the Effectiveness of Myopia Control Lenses in Slowing Myopia Progression in Young Children
This study will be a mono-center, single-arm, unmasked study evaluating the effectiveness of test lens in slowing myopia progression in children aged 6 to 8 years.
- Trial name
- NCT06857864
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Essilor International