Clinical trials: Eye Movements
Strabismus
Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Patients With Strabismus
Primary objective is to evaluate the efficacy of single-dose treatment with GSK1358820 compared with non-treatment in patients with strabismus based on angles of strabismus in the primary position.
- Trial name
- NCT01584843
- Testing
- GSK1358820
- Where
- 13 sites in Japan
- Volunteers
- 41 people
- Sponsor
- GlaxoSmithKline
Strabismus
Deep Neuromuscular Blockade in Strabismus Surgery
The purpose of this study is to determine if inducing a moderate or greater neuromuscular block (TOF count 0-3) when performing a neuromuscular block in pediatric patients aged 3 to 18 years undergoing strabismus surgery under…
- Trial name
- NCT05882643
- Testing
- moderate to deep neuromuscular blockade, shallow to minimal neuromuscular blockade
- Where
- South Korea
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Amblyopia
Morning Versus Evening Patching in Childhood Amblyopia
To determine whether the time of day at which daily occlusion therapy is administered-morning, with 2 hours of patching completed within 07:00-10:00, versus evening, with 2 hours completed within 17:00-20:00-affects visual-acuity…
- Trial name
- NCT07294599
- Testing
- eye-patching
- Where
- 2 sites in Jordan
- Volunteers
- 84 people
- Sponsor
- Yarmouk University
Guillain-Barré Syndrome, Miller Fisher Syndrome
International Guillain-Barré Syndrome Outcome Study
International GBS Outcome Study (IGOS) is a study conducted by the members of the Inflammatory Neuropathy Consortium (INC) and Peripheral Nerve Society (PNS) on disease course and outcome in Guillain-Barré syndrome (GBS).
- Trial name
- IGOS (NCT01582763)
- Where
- 138 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people
- Sponsor
- Erasmus Medical Center
Intermittent Strabismus, Exotropia Intermittent
Visual Therapy for Intermittent Strabismus
Intermittent strabismus is a condition in which the eyes occasionally become misaligned, affecting binocular vision, depth perception, and quality of life.
- Conditions
- Intermittent Strabismus, Exotropia Intermittent, Esotropia Intermittent
- Trial name
- ViT(I)S (NCT07563959)
- Testing
- Visual Therapy
- Volunteers
- 30 people
- Sponsor
- Universitat Politècnica de Catalunya
Progressive Supranuclear Palsy
Art Therapy in Progressive Supranuclear Palsy
Our aim is to study the effect of art therapy for people with PSP, with a focus on alleviating the symptoms associated with PSP, enhancing the overall quality of life for patients, and reducing caregiver stress.
- Trial name
- NCT06588673
- Testing
- Art Thrapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University Medical Center
Amblyopia, Strabismus
VISION-3D: Visual Skills Improvement With On-screen 3D Movies.
This clinical study investigates whether watching 3D films can help improve the vision of children with residual amblyopia (lazy eye), that is, those children who, despite having undergone usual treatments such as glasses or…
- Trial name
- VISION3D (NCT07301645)
- Testing
- Stereoscopic (3D) Movie Viewing, 2D Movie Viewing
- Volunteers
- 40 people
- Sponsor
- Universitat Politècnica de Catalunya
Post-Traumatic Stress Disorder, Depressive Symptoms
Efficacy of EMDR Versus CBT for Post-Traumatic Stress and Comorbid Disorders in Pakistan: A Randomized Controlled Feasibility-Pilot Study
Post-Traumatic Stress Disorder (PTSD) is commonly accompanied by symptoms of depression and anxiety. Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT) are evidence-based psychological…
- Conditions
- Post-Traumatic Stress Disorder, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT04021329
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Trauma-Focused Cognitive Behavioral Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Craniosynostosis, Strabismus
Ocular Characteristics in Patients With Craniosynostosis
Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births.
- Conditions
- Craniosynostosis, Strabismus, Intracranial Hypertension, Amblyopia
- Trial name
- COPACA (NCT06928727)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Childhood Absence Epilepsy, Absence Seizures
Assessing Comorbidities in Epilepsy Using Eye Movement Recordings
This study wants to make it easier to find kids with a type of epilepsy called childhood absence epilepsy (CAE) who might have problems with ongoing seizures and thinking.
- Conditions
- Childhood Absence Epilepsy, Absence Seizures, Epilepsy Comorbidities
- Trial name
- ACER (NCT06310772)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eysz, Inc.
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using Retinal Birefringence Imaging
The purpose of this project is to compare the accuracy of two products at detecting amblyopia and strabismus in children. The devices will be Rebiscan's "blinq" (Pediatric Vision Scanner; PVS) and Rebiscan's RBI (Retinal…
- Trial name
- RBI (NCT03919708)
- Testing
- Retinal Birefringence Imager
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Blepharospasm, Dystonia
Mexiletine for the Treatment of Focal Dystonia
Dystonia refers to a condition characterized by involuntary muscle contractions that may cause pain, abnormal posture, or abnormal movements.
- Conditions
- Blepharospasm, Dystonia, Spasm
- Trial name
- NCT00001784
- Testing
- Mexiletine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Ondansetron Lozenge, Postoperative Nausea and Vomiting
Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint Surgeries
The aim of this study is to evaluate the role of ondansetron lozenge on prevention of postoperative nausea and vomiting (PONV) in pediatrics undergoing squint surgeries.
- Conditions
- Ondansetron Lozenge, Postoperative Nausea and Vomiting, Pediatrics, Squint
- Trial name
- NCT06423820
- Testing
- Ondansetron lozenge
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
ADHD, Convergence Insufficiency
Study of Eyes and Attention Deficit (SEAD)
Attention-Deficit Hyperactivity Disorder (ADHD) is considered to be one of the most prevalent chronic health conditions in children. It affects between 4% and 12% of young children.
- Conditions
- ADHD, Convergence Insufficiency, Accommodative Insufficiency
- Trial name
- NCT00472511
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Neurodegenerative Diseases, Parkinson Disease
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
MARKERS-NDD is a prospective, observational, longitudinal study, which aims to collect data from patients affected by neurodegenerative diseases (NDD) followed longitudinally for routine examinations performed as part of normal…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
- Trial name
- MARKERS-NDD (NCT06596746)
- Testing
- Observation
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Casa di Cura San Raffaele Cassino
Education, Education, Medical, Undergraduate
3D Eye Movement Simulator for Medical Education
The goal of this clinical trial is to evaluate whether a new 3D-printed eyeball movement simulator improves medical education compared to traditional teaching methods.
- Conditions
- Education, Education, Medical, Undergraduate, Education, Medical
- Trial name
- NCT07031960
- Testing
- 3D Eyeball Movement Simulator Group, Conventional Teaching Methods Group
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Autistic Disorder, Autism Spectrum Disorder
Training Attention and Eye Movement in ASD
Current therapies for autism target social and language behaviors, but due to the high-level nature of these skills any improvement rarely extends beyond the targeted behavior.
- Trial name
- NCT02403817
- Testing
- Cognitive Training, Eye Motor Training, Hand Motor Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Diego
Myopia, Strabismus
A Trial of Bifocals in Myopic Children With Esophoria
To test the hypothesis that correction with bifocal spectacle lenses rather than single-vision lenses will slow the progression of myopia in children with near-point esophoria.
- Conditions
- Myopia, Strabismus, Esophoria
- Trial name
- NCT00000128
- Testing
- Bifocal Spectacle Lenses
- Sponsor
- National Eye Institute (NEI)
Convergence Insufficiency
Randomized Trial of Treatments for Convergence Insufficiency
The Convergence Insufficiency Treatment Trial (CITT) is a multi-center, placebo-controlled, single-masked, clinical trial designed to compare the benefits of two commonly used treatment approaches for patients with convergence…
- Trial name
- NCT00347945
- Testing
- Pencil Push-ups, Office-based Vision Therapy
- Where
- 7 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pennsylvania College of Optometry
Neuroblastoma, Opsoclonus-myoclonus
Use of Rituximab in Opsoclonus-Myoclonus in Children With Neuroblastoma
The purpose of this study is to evaluate the feasibility of giving four weekly doses of Rituximab (anti-CD20 antibody) in the treatment of children with refractory neuroblastoma associated opsoclonus-myoclonus.
- Trial name
- NCT00202930
- Testing
- anti-CD20 (Rituximab)
- Volunteers
- 4 people
- Sponsor
- Jean M. Tersak, M.D.