Clinical trials: Family Member
Bipolar Disorder (BD), Bipolar Disorder I or II
FOCUS Bipolar: Families Opening Conversations for Understanding Signs
Bipolar disorder often runs in families, but early symptoms in youth can go unrecognized for years. This project evaluates a structured, family-centered approach to informed screening for youth ages 7-21 who have a biological…
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder I or II, Bipolar Disorder Family Members, Screening Tool
- Trial name
- FOCUS Bipolar (NCT07622927)
- Testing
- Co-design Workshop (Observational Procedure), Alpha Testing (Observational Procedure), Beta Testing (Observational Procedure)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Nonmalignant Pain
Family Nursing Conversations Patients With Chronic Non-Cancer Pain
This study assumes that family nursing will enhance the management of chronic nonmalignant pain (CNP) for the patients and their family members.
- Trial name
- FANCOC-PAIN (NCT03981302)
- Testing
- Family nursing conversations
- Where
- Denmark
- Volunteers
- 143 people
- Sponsor
- Bente Appel Esbensen
Gastric Cancer
Expression of S100A2 and Trefoil Factor Family Members in Epstein-Barr Virus Related Gastric Cancer
The investigators hypothesize that aberrant hypermethylation of tumour suppressor genes is an important mechanism for Epstein-Barr Virus (EBV) - related gastric carcinogenesis, the promoter hypermethylation status and the…
- Trial name
- NCT01100814
- Where
- Singapore
- Sponsor
- National University Hospital, Singapore
Neoplasms, Hematologic Neoplasms
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
This study will collect biological samples for use in research experiments aimed at better understanding the clinical features of certain diseases.
- Conditions
- Neoplasms, Hematologic Neoplasms, Healthy Volunteers
- Trial name
- NCT00071045
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myotonic Dystrophy, Facioscapulohumeral Muscular Dystrophy
Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are inherited disorders characterized by progressive muscle weakness and loss of muscle tissue.
- Conditions
- Myotonic Dystrophy, Facioscapulohumeral Muscular Dystrophy, Muscular Dystrophy, Myotonic Dystrophy Type 1
- Trial name
- NCT00082108
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Coronavirus, Anxiety Depression
When Distance is an Act of Love: Exploring the Use of Video Diaries for Family Members of Intensive Care Patients
Due to Covid-19, intensive care (ICU) patients are not allowed visitors or have severely restricted visiting. After being admitted to ICU most patients are unconscious or extremely weak and therefore cannot speak on a phone or…
- Trial name
- NCT04870450
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Gastric Cancer, Genetic Predisposition
Research for Associated Genes for Gastric Cancer in Family Member With Affected First-Degree Relatives
Familial gastric cancer accounts for 10% of all cases, but predisposing genetic variations is unknown except for CDH1 mutation. Because Germline mutation is believed to be a key aspect of cancer predisposition, we plan to recruit…
- Trial name
- NCT03486574
- Testing
- Positive result from pathological test
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Anemia, Aplastic, Amegakaryocytic Thrombocytopenia
Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias
Due to an overall and disease free survival of 85% to 100%, allogeneic blood or bone marrow stem cell transplantation using an HLA matched sibling donor is the therapy of choice for patients with severe aplastic anemia (SAA).
- Conditions
- Anemia, Aplastic, Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Kostmann Syndrome
- Trial name
- NCT00244010
- Testing
- Allogeneic stem cell transplant
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- St. Jude Children's Research Hospital
Osteosarcoma, Paget's Disease
Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18:
Researchers have previously demonstrated loss of heterozygosity in a region on chromosome 18q, associated with osteogenic sarcomas in bone affected by Paget's disease.
- Trial name
- NCT00615628
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Onychomycosis, Tinea Pedis
Spread of Dermatophytes Among Families
The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.
- Trial name
- NCT00233493
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Rare Disease, Idiopathic Disease
Idiopathic Diseases of Man
This research is being done to learn more about possible genetic causes of currently undiagnosed conditions, and to find out how the development of new technologies, such as DNA sequencing, can increase knowledge of the role…
- Trial name
- IDIOM (NCT01440218)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Scripps Translational Science Institute
Psychosis, Suicide
Youth Nominated Support Team
This study aims to adapt the current Youth-Nominated Support Team (YST) manual used to treat suicide risk for people at clinical high risk for psychosis.
- Conditions
- Psychosis, Suicide, Health Care Utilization, Family Members
- Trial name
- YST (NCT05558332)
- Testing
- Youth-Nominated Support Teams for CHR
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, Irvine
Breastfeeding
The Effect of Breastfeeding Education Given to Family Members on Breastfeeding Parameters
The Effect of Breastfeeding Education Given to Family Members Who Support the Mother in the Postpartum Period on Breastfeeding Parameters. Istanbul University-Cerrahpaşa Graduate Education Institute, Midwifery Department.
- Trial name
- NCT06119828
- Testing
- breastfeeding education for family members, receiving routine breastfeeding training
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people
- Sponsor
- Selcuk University
Family Members, Dependence
Behavioral Problems Related to Attendance Adult Day Care Centers
Adult Day Care Centers (ADCC) offer important relief and rest services for family caregivers. However, some caregivers report that behavioral and psychological symptoms of dementia (BPSD) arise when they prepare dependents for…
- Trial name
- PROCENDIAS (NCT03057184)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency, Autosomal Recessive Hypophosphatemic Rickets
The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency
The primary purpose of Study INZ701-104 (the ENERGY study) is to assess the safety and tolerability of INZ-701 in infants with ENPP1 Deficiency or with ABCC6 Deficiency.
- Conditions
- Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency, Autosomal Recessive Hypophosphatemic Rickets, Generalized Arterial Calcification of Infancy, ATP-Binding Cassette Subfamily C Member 6 Deficiency
- Trial name
- ENERGY (NCT05734196)
- Testing
- INZ-701
- Where
- 5 sites in United States, Spain and 1 more
- Volunteers
- 9 people
- Sponsor
- Inozyme Pharma
Family Members, Adolescent Problem Behavior
Representations and Strategies of Families Faced With Radicalisation Process
Objectives: This study aims to explore families' representations and strategies about their teenagers or young adults involved in the radicalisation process and use these findings to build specific tools to help professionals…
- Conditions
- Family Members, Adolescent Problem Behavior, Qualitative Research, Young Adult
- Trial name
- FamRad (NCT03782597)
- Testing
- Semi-structured interviews or focus groups to explore families representations and strategies about their teenagers involved in radicalisation process
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Mutualiste Montsouris
Influenza
Acute Respiratory Infection Consortium
Recently, the emergence and rapid global dissemination of novel swine-origin influenza A virus (H1N1) with unique epidemiologic characteristics has heightened awareness and concern of this viral pathogen, and its potential for…
- Trial name
- ARIC (NCT01021098)
- Where
- 5 sites in United States
- Volunteers
- 2,018 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation
AVTX-801 D-galactose Supplementation in SLC35A2-CDG
This is a multicenter, randomized, double-blind, placebo-controlled, cross-over study to evaluate the efficacy and safety of AVTX-801 in subjects with SLC35A2-CDG
- Trial name
- NCT05402384
- Testing
- AVTX-801
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Eva Morava-Kozicz
Respiratory Distress Syndrome, Newborn
Genetic Regulation of Surfactant Deficiency
Inherited deficiencies in any one of 3 genes (surfactant protein B, surfactant protein C, and ATP-binding cassette transporter A3) can cause neonatal respiratory distress syndrome by disrupting metabolism of the pulmonary…
- Trial name
- NCT00828243
- Testing
- Nutrient
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- Washington University School of Medicine
According to the IRB Approval
NVC Test in Order to Assess Pathological Changes in Family Members of Patient Diagnosed With SSc
Systemic sclerosis (SSc) is multisystem autoimmune disease of unknown etiology. It's characterized by activation of immune system, microvascular changes and intimal proliferation.
- Trial name
- SSc NVC (NCT02795221)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center