Clinical trials: Family Research
Family, Well-being
A Community-based Family Holistic Health Promotion Project in Hong Kong: A Cluster Randomized Controlled Trial (cRCT)
In Hong Kong, nearly 40% of adults were overweight or obese, and about 60% of total registered deaths were due to four major preventable non-communicable diseases.
- Conditions
- Family, Well-being, Physical Activity, Healthy Diet
- Trial name
- NCT02866773
- Testing
- PA1: Education sessions, Reminders, Whataps group, PA2: Education sessions, Reminders, PA3: Education sessions, Whataps group
- Where
- Hong Kong
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pediatric Obesity, Attrition
Stay In Treatment for Pediatric Weight Management
Attrition from pediatric weight management programs is unacceptably high, with dropout ranging from 27-73%. This project will utilize a model that predicts dropout from treatment, increasing its power and accuracy through a…
- Conditions
- Pediatric Obesity, Attrition, Family Research, Weight Loss
- Trial name
- SIT (NCT04364282)
- Testing
- Care team informed, Control
- Where
- 2 sites in United States
- Volunteers
- 1,216 people
- Sponsor
- Wake Forest University Health Sciences
Childhood Obesity
Mountain West Prevention Research Center Core Research Project
This hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial will assess the impact of integrating population health management (PHM) strategies-text messaging and enrollment in Building Healthy…
- Trial name
- MW-PRCCRP (NCT07479498)
- Testing
- Text Message-based recruitment, Active outreach follow-up
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Paul Estabrooks
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory.
- Conditions
- Childhood Atypical Teratoid/Rhabdoid Tumor, Childhood Central Nervous System Germ Cell Tumor, Childhood Cerebral Anaplastic Astrocytoma, Childhood Cerebral Astrocytoma
- Trial name
- NCT00919750
- Testing
- Cytology Specimen Collection Procedure
- Where
- 187 sites in United States, Australia and 4 more
- Volunteers
- 1,258 people
- Sponsor
- Children's Oncology Group
Cardiovascular Diseases, Heart Diseases
Quantitative Genetic Analysis of Lipid Research Clinic Family Data
To assess the mode of inheritance of familial combined hyperlipidemia and familial primary hypoalphalipoproteinemia and to resolve genetic and familial environmental effects on several phenotypes of importance to coronary heart…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Tangier Disease
- Trial name
- NCT00005188
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Tuberculosis Infection, Latent, Tuberculosis Active
SCAF-TB - Saving Children and Their Families From Tuberculosis: Implementation Research to Improve TB Preventive Treatment Initiation and Completion Rates Among Contact Persons in Tajikistan and Tanzania
The SCAF-TB study aims to evaluate how the WHO-endorsed SIILTIBCY skin test can be best implemented to test close contacts for tuberculosis infection (TBI) in Tajikistan and Tanzania, either facility-based or home-based delivered…
- Conditions
- Tuberculosis Infection, Latent, Tuberculosis Active, TPT
- Trial name
- SCAF-TB (NCT07714707)
- Testing
- CY-TB Patch, Audiblehealth DX
- Where
- 2 sites in Tajikistan, Tanzania
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- KNCV Tuberculosis Foundation
Adverse Childhood Experiences
Family Resilience Initiative Research Program
University Le Bonheur Pediatric Specialists (ULPS) and Le Bonheur Community Health and Well-Being, Maternal Child Department, have started the Family Resilience Initiative (FRI) in the ULPS General Pediatrics Clinic.
- Trial name
- NCT04018404
- Testing
- FRI CLINICAL PROGRAM
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Mental Disorders, Psychological Disorders
Longitudinal Family/Molecular Genetic Study to Validate Research Domain Criteria
The purpose of this research is to study new ways of classifying mental disorders in children based on observable behavior and genetics to ultimately diagnose these disorders better.
- Conditions
- Mental Disorders, Psychological Disorders, Psychiatric, Diagnosis, Mental Disorders Diagnosed in Childhood
- Trial name
- NCT02415647
- Where
- United States
- Volunteers
- 2,806 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Parenting, Family Research
More Appreciation and Less Criticism Project
The project "More Appreciation and Less Criticism Project" (MALC) is a collaboration between the Tung Wah Group of Hospitals (TWGHs) and the School of Public Health of The University of Hong Kong (HKUSPH), funded by The Hong Kong…
- Conditions
- Parenting, Family Research, Family
- Trial name
- NCT04445818
- Testing
- More appreciation, Less criticism, More Fruit and Vegetable
- Volunteers
- 803 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Obesity
Church, Extension and Academic Partners Empowering Healthy Families
The project will address health disparities via a community-engaged approach in partnership with black churches. The long-term goals of this integrated project are to: 1) prevent and reduce childhood obesity through improved…
- Trial name
- EHF (NCT03980262)
- Testing
- Healthy Children, Healthy Families+ (HCHF+), Money Smart
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Family Health, Happiness and Harmony, Physical Health
Happy Family Kitchen Movement Project
In recent years, Hong Kong is undergoing rapid changes together with macro social and economic trends. The increasingly complex and diverse family structure is leading to a major concern in the well-being of families, including…
- Conditions
- Family Health, Happiness and Harmony, Physical Health, Psychosocial Health, Family Communication
- Trial name
- HFKM (NCT02563613)
- Testing
- Physical Exercise (PE), Healthy Diet (HD), Wait-list Control (C)
- Where
- China
- Volunteers
- 3,419 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Comparison Group, Multiple Family Groups by Parent Peers
SMART Africa (Strengthening Mental Health Research and Training)
The objective of this research study is to examine the implementation of and outcomes associated with an evidence-based practice (EBP), specifically Multiple Family Group (MFG) targeting youth disruptive behavior challenges and…
- Conditions
- Comparison Group, Multiple Family Groups by Parent Peers, Multiple Family Groups by Community Health Workers
- Trial name
- SMART (NCT03081195)
- Testing
- MFG
- Where
- 4 sites in United States, Ghana and 2 more
- Volunteers
- 3,117 people
- Sponsor
- Washington University School of Medicine
Early Nursing Intervention, Gestational Diabetes Mellitus
The Role of Early Nursing Intervention in the High-risk Population of Gestational Diabetes
Pregnant women who established prenatal examination cards in the prenatal outpatient department of our hospital from January 2025 to September 2025 were selected.
- Trial name
- NCT06997835
- Testing
- Control group：The interactive management nursing model on the wechat platform, Intervention group：Family-centered early care intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Yan Lu
Cardiovascular Diseases
The BRAVE Study- The Identification of Genetic Variants Associated With Bicuspid Aortic Valve Using a Combination of Case-control and Family-based Approaches.
Bicuspid aortic valve (BAV) is the most common congenital heart anomaly in the general population (1-2% of all individuals). In affected people, the aortic valve (the structure ensuring one way blood flow between the heart's left…
- Trial name
- BRAVE (NCT04514445)
- Testing
- Observational
- Where
- 4 sites in United Kingdom
- Volunteers
- 700 people
- Sponsor
- University Hospitals, Leicester
Down Syndrome
Correlations Phenotype / Genotype in Down Syndrome
The purpose of this study is to correlate phenotype and genotype of Down syndrome patients in order to identify the biochemical reactions involved in their mental retardation and their other phenotypic characteristics.
- Trial name
- INTREPID (NCT01034280)
- Where
- France
- Volunteers
- 524 people
- Sponsor
- Institut Jerome Lejeune
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Darier Disease, Hailey-Hailey Disease
National Registry for Ichthyosis and Related Disorders
The ichthyoses are a family of genetic skin diseases characterized by dry, thickened, scaling skin. Dermatologists estimate that there are over twenty varieties of ichthyosis, with a wide range of severity and associated…
- Conditions
- Darier Disease, Hailey-Hailey Disease, Hyperkeratosis, Epidermolytic, Ichthyosis
- Trial name
- NCT00074685
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Liver Failure
Understanding Patient's Knowledge and Use of Acetaminophen
Introduction to Study Objectives: In a joint collaboration of the Centers for Education and Research on Therapeutics (CERTS) at The University of Pennsylvania and the M.D.
- Trial name
- NCT00823758
- Testing
- Focus Groups, Personal Interviews
- Where
- 4 sites in United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center