Clinical trials: Fatty Acids
ADHD
Omega-3 Fatty Acids Supplementation in ADHD
The overarching aim of the proposed study is to assess whether omega-3 fatty acids supplementation can augment the effects of methylphenidate in children with ADHD.
- Trial name
- NCT01777048
- Testing
- Omega-3 Fatty Acids Supplementation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Lysosomal Acid Lipase Deficiency, Wolman Disease
Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency
This was an open-label, repeat-dose, intra-participant dose-escalation study of SBC-102 (sebelipase alfa) in children with growth failure due to lysosomal acid lipase (LAL) Deficiency.
- Trial name
- NCT01371825
- Testing
- Sebelipase alfa (SBC-102)
- Where
- 7 sites in United States, Egypt and 3 more
- Volunteers
- 9 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Attention Deficit Hyperactivity Disorder
The Effects of DHA on Attention Deficit and Hyperactivity Disorder
The purpose of this study is to determine whether docosahexaenoic acid (DHA) is effective in reducing Attention Deficit/Hyperactivity Disorder (ADHD) core symptoms in a clinical sample of children and adolescents with ADHD.
- Trial name
- DADA (NCT01796262)
- Testing
- docosahexaenoic acid, Wheat germ oil
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Eugenio Medea
Cardiovascular Diseases, Coronary Disease
Trends in Trans-Fatty Acid Intake Between 1980 and 1997
To examine trends in trans-fatty acid intake by using newly available nutrient data to recalculate 24 dietary recalls from the Minnesota Heart Survey.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00006500
- Sponsor
- University of Minnesota
Microbial Colonization, Infant Development
The Effects of Omega-3 PUFAs on the Infant Microbiome and Immunity
Prenatal supplementation with fish oil, rich in omega-3 polyunsaturated fatty acids, is widely recommended in Canada. The aim of this observational, prospective cohort study is to determine the effects of maternal fish oil…
- Trial name
- NCT03297801
- Testing
- Fish oil supplements
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Iron Deficiency, Anemia
The Effects of Iron and Omega-3 Fatty Acid Supplementation on Cognition and Immune Function in Iron Deficient Children
The aim of this study is to determine if providing iron and a mixture of DHA and EPA, alone and in combination, to children with iron deficiency and poor n-3 fatty acid intake will improve their cognitive performance, activity…
- Trial name
- FeFA (NCT01092377)
- Testing
- DHA and EPA Fish Oil capsule, Iron tablet
- Where
- South Africa
- Volunteers
- 320 people
- Sponsor
- North-West University, South Africa
Eating Disorders in Adolescence, Eating Disorders in Children
A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From Psychoneuroimmunology
The goal of this observational study is to learn if behavioral and psychological factors are associated with the intestinal microbiota composition and function in children and adolescents with eating disorders (ED).
- Trial name
- PSYNIGED (NCT07066033)
- Where
- 2 sites in Spain
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Esther Nova
Healthy
Health Professional Dietary Habits and Blood Omega-3 Fatty Acid Concentrations
Health professionals attending the American Association for Family Physicians (AAFP) meeting at the Orlando Convention Center, Sept 21-23, 2016 who visit the DSM Nutritional Products Inc booth will be invited to complete an…
- Trial name
- NCT03056898
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Autism Spectrum Disorders
Dietary Fatty Acids Improve Social Impairment in Autism Spectrum Disorders
In a double-blind, placebo-controlled 16-week trial investigators administered daily doses of either youths with autism spectrum disorders.ARA and DHA supplementation significantly improved communication as well as social…
- Trial name
- Fatty acid (NCT01154894)
- Testing
- Aravita including arachidonic acid and docosaheaenoic acid
- Volunteers
- 13 people
- Sponsor
- Ashiya University
Autism Spectrum Disorder
Effect of Omega-3 Fatty Acid on Neurobehavioral Status of Children With Autism Spectrum Disorder: A Randomized, Double-Blind, Placebo Controlled Trial
This study is conducted to assess whether Omega-3 fatty acid improves neurobehavioral staus of children with Autism Spectrum Disorder and whether there is any correlation of this improvement with reference range of Omega-3 fatty…
- Trial name
- NCT06125782
- Testing
- Omega 3 fatty acid
- Where
- Bangladesh
- Volunteers
- 64 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Type 1 Diabetes
Cord Blood Plus Vitamin D and Omega 3s in T1D
In this pilot study the investigators are trying to see if a single intravenous infusion of autologous (self) cord blood cells followed by 1 year of daily vitamin D and omega 3 fatty acid supplementation can preserve beta cell…
- Trial name
- NCT00873925
- Testing
- Autologous UCB, Omega 3 FA, Vitamin D
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Preterm Infants, Parenteral Nutrition n-3 Fatty Acids
Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants
The study shall provide evidence for the save and efficient use of a fish oil containing lipid emulsion in parenteral nutrition of preterm infants.Safety will be assessed by monitoring hepatological and hematological laboratory…
- Trial name
- NCT00497289
- Testing
- Lipofundin MCT/LCT 20 %, Lipidem 20%
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- B. Braun Melsungen AG
Attention Deficit Hyperactivity Disorder, Deficient Emotional Self-Regulation
Omega-3 Supplementation to ADHD Medication in Children
This study is a 12-week open-label trial to assess the effectiveness of Omega-3 fatty acids for deficient emotional self-regulation (DESR) as a supplement to Attention Deficit/Hyperactivity Disorder (ADHD) treatment in children…
- Trial name
- NCT02204410
- Testing
- Omega-3 Fatty Acid, ADHD Medication
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Massachusetts General Hospital
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Children With ADHD Symptoms >90th Percentile (FBB-ADHS-V); no Beginning or Completion of Psychotherapeutically or Psychopharmalogical Treatment During the Study
Efficacy of Omega-3/Omega-6 Fatty Acids in Pre-school Children at Risk for ADHD
The efficacy of PUFAs (as nutritional supplement) in/for pre-school children with ADHS symptoms will be evaluated in a randomised controlled doubleblind trail with children aged 3-6 years.
- Trial name
- NCT01795040
- Testing
- omega-3/omega-6 fatty acids (PUFAs)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Cologne
Infant Development
Effect of a Mix of Dairy Lipids and Plant Oils in Infant Formula on Omega-3 Fatty Acid in Red Blood Cells
The objective of this study is to determine whether the use of a mix of dairy lipids and plant oils in infant formula can increase the sum of omega-3 fatty acids levels in membrane phospholipids of red blood cells (RBC) in 4…
- Trial name
- REBECA (NCT01611649)
- Testing
- Formula containing dairy lipids and plant oils, Formula containing plant oils, Formula containing dairy lipids and plant oils, DHA+ARA
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Lactalis
Blood Pressure
Effect of High-carbohydrate or High-monounsaturated Fat on Blood Pressure: Meta-analysis of Randomized Clinical Trials
High saturated fat acids diets are associated with elevated blood pressure which is associated with cardiovascular morbidity and mortality.
- Trial name
- CHO-MUFA (NCT02626325)
- Testing
- High-carbohydrate or High-monounsaturated fat diets
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Aerobic Endurance, Metabolism
Effect of Short-chain Fatty Acids on Aerobic Endurance
Randomized, double-blind, placebo-controlled crossover study designed to determine the effects of increasing colonic short-chain fatty acid (SCFA) content on aerobic endurance in healthy adults, and to identify underpinning…
- Trial name
- NCT06054607
- Testing
- High-amylose maize starch+acetate/butyrate, Low-amylose maize starch
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Cystic Fibrosis
Use of Formula Fortified With DHA in Infants With Cystic Fibrosis
The hypothesis of this study is that feeding infants diagnosed with CF via newborn screening a formula enhanced with a specific fish-oil fatty acid known as DHA will improve growth and decrease pancreatic dysfunction (as measured…
- Trial name
- DHA (NCT00530244)
- Testing
- Docosahexaenoic acid (DHA), Standard formula (Enfamil)
- Where
- 24 sites in United States
- Volunteers
- 76 people
- Sponsor
- University of Massachusetts, Worcester
Infant Development
Effect of Long-Chain Polyunsaturated Fatty Acid Supplementation on Toddler Cognition
The hypothesis to be examined is that dietary LCP-supplementation in the second and third years of life will improve cognitive and visual maturation in early childhood.
- Trial name
- NCT00982462
- Testing
- Docosahexaenoic acid (DHA) and arachidonic acid (ARA)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Retina Foundation of the Southwest