Clinical trials: Feasibility Pilot Study
Nicotine Vaping
Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping
The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents.
- Trial name
- YES-CAN! (NCT07009509)
- Testing
- YES-CAN! program
- Where
- United States
- Volunteers
- 1,166 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Mental Disorders During Pregnancy
Efficacy and Feasibility of Baby Triple P - a Pilot Study
In the present pilot study the feasibility and efficacy of Baby Triple P- an antenatal parent training- are investigated. Healthy becoming first time parents were randomly allocated to either the Baby Triple P parent-training…
- Trial name
- NCT02313493
- Testing
- Baby Triple P
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Obesity Prevention, Healthy Lifestyle Behaviors
Feasibility of a Healthy Lifestyle Program (Athletes for Life) in Mexicali, Baja California
Childhood obesity affects 36.6% of children in Mexico and nearly 50% in Baja California. Traditional weight-centered interventions yield modest and unsustainable results.
- Trial name
- NCT07847645
- Testing
- Healthy lifestyle program, Control group
- Where
- Mexico
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus of Childhood
Fitness Integrative Training for Pediatric Rheumatology Disorders
This study evaluates the feasibility of the Fitness Integrative Training program for Teens (FIT Teens 2), a combined cognitive behavioral therapy and neuromuscular exercise training program in patients with pediatric rheumatic…
- Conditions
- Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus of Childhood, Joint Hypermobility, Juvenile Dermatomyositis
- Trial name
- FIT Teens 2 (NCT06556992)
- Testing
- FIT Teens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Treatment Adherence
Pilot Study of a Transition Intervention for ALWH
The investigators will conduct a pilot study of a community-based intervention designed to improve outcomes among adolescents living with HIV (ALWH) transitioning to adult HIV care in Lima, Peru.
- Trial name
- PASEO (NCT05022706)
- Testing
- Community-based accompaniment and home visits, Directly Observed Therapy, Monthly Peer Support Groups
- Where
- 3 sites in Peru
- Volunteers
- 30 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Acute Pain, Procedural Anxiety
Little NIRVANA for Pediatric Pain and Anxiety
The aim of this study is to test the feasibility of using Little NIRVANA (augmented reality (AR)) for managing anxiety and pain for children 2-8 years old during hospital emergency peripheral intravenous (PIV) insertions.
- Conditions
- Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine
- Trial name
- NCT06795126
- Testing
- Little NIRVANA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
IV Insertion in the Emergency Department
Immersive Virtual Reality to Reduce Procedural Pain During IV Insertion in Children in the Emergency Department
Venipuncture and intravenous (IV) access continue to be the most common causes of pain and distress among children in the pediatric emergency department.
- Trial name
- NCT03435367
- Testing
- Virtual Reality Program, iPad Tablet
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- The Hospital for Sick Children
Concussion, Mild
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the sub-acute period after concussion, and to document the…
- Trial name
- Breathe (NCT06559865)
- Testing
- Breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Kidney Transplant, Urinary Tract Infection(UTI)
Antibiotics for Kidney Transplant Recipients
The goal of this clinical trial is to learn if a common antibiotic called trimethoprim-sulfamethoxazole (TMP-SMX) can help prevent urinary tract infections (UTIs) in children and young adults who recently had a kidney transplant.
- Conditions
- Kidney Transplant, Urinary Tract Infection(UTI), Antibiotic Prophylaxis, Remote Patient Monitoring
- Trial name
- TASK (NCT07106125)
- Testing
- Trimethoprim-Sulfamethoxazole (TMP-SMX), Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Methylation, Body Composition
Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers
Background: Researchers want to collect information on diet, physical activity, and sun exposure in children and young adults. The data can provide information on the effect these factors might have on the development of cancer…
- Conditions
- Methylation, Body Composition, Physical Activity, Puberty
- Trial name
- NCT01517139
- Where
- China
- Volunteers
- 278 people
- Sponsor
- National Cancer Institute (NCI)
Anterior Cruciate Ligament Injury, Quadriceps Dysfunction
Exercise Loading Biology Post-Traumatic OsteoArthritis Study - a Pilot and Feasibility Study
FROM RISK FACTORS TO THE PREVENTION OF LONG-TERM CONSEQUENCES AFTER CRUCIATE LIGAMENT INJURY (ACL injury) - This is a research project where we seek new knowledge about why some people have a high risk and others a low risk of…
- Conditions
- Anterior Cruciate Ligament Injury, Quadriceps Dysfunction, Knee Joint Loading, Anterior Cruciate Ligament Reconstruction
- Trial name
- ExeLoadBioPTOA (NCT06892899)
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- May Arna Risberg
Patient Safety, Manipulation, Spinal
(MIST1)-Part 1: Assessment & Feasibility of Post-Symptoms Evaluation
To increase patient safety culture in spinal manipulation therapy (SMT) this study will assess the ability to implement an active surveillance reporting system for a chiropractic teaching clinic and determining preliminary…
- Trial name
- MIST1 (NCT03412097)
- Testing
- active surveillance
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Parker University
Alzheimer's Dementia, Neuropsychiatric Symptoms Related to Neurodegenerative Disease
Feasibility of Wearables in Dementia Care in Rural Taiwan
Taiwan is becoming a super-aged society, and more older adults are living with Alzheimer's disease. Many people with Alzheimer's experience behavioral and psychological symptoms, such as agitation, sleep problems, or mood…
- Conditions
- Alzheimer's Dementia, Neuropsychiatric Symptoms Related to Neurodegenerative Disease, Wearable Devices, Caregiver Burden of People With Dementia
- Trial name
- NCT07249918
- Testing
- Re-Timer (light therapy glasses)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Lymphoma
Whole Body PET-MRI in Paediatric and Adolescent Lymphoma
Children and adolescents with Hodgkin lymphoma currently undergo multiple investigations including a separate PET and MRI scans during their treatment.
- Trial name
- PET/MRI (NCT02935348)
- Testing
- Whole Body MRI
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University College, London
Adult Anaplastic Astrocytoma, Recurrent Grade III Glioma
A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas
RATIONALE: Genetically-modified neural stem cells (NSCs) that convert 5-fluorocytosine (5-FC) into the chemotherapy agent 5-FU (fluorouracil) at sites of tumor in the brain may be an effective treatment for glioma.
- Conditions
- Adult Anaplastic Astrocytoma, Recurrent Grade III Glioma, Recurrent Grade IV Glioma, Adult Anaplastic Oligodendroglioma
- Trial name
- NCT01172964
- Testing
- flucytosine, polymerase chain reaction, immunohistochemistry staining method
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- City of Hope Medical Center
Type 1 Diabetes Mellitus
Nutritional Prevention Pilot Trial for Type 1 Diabetes
The overall objective of the study is to assess whether complete avoidance of cow's milk (CM) proteins, for at least the first 6 months of life, prevents type 1 diabetes (insulin-dependent diabetes mellitus, IDDM) in genetically…
- Trial name
- MIP (NCT00570102)
- Testing
- A highly hydrolyzed formula, A regular cow's milk based formula
- Where
- 18 sites in Finland
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Neurogenic Bowel, Spinal Cord Injuries (SCI)
Transcutaneous Spinal Cord Stimulation for Bowel Management in Individuals with Motor Complete Spinal Cord Injury
The primary goals of this pilot trial are to understand the feasibility and safety of thoracolumbar transcutaneous spinal cord stimulation for neurogenic bowel management in individuals with new onset, traumatic, cervicothoracic…
- Trial name
- NCT06801431
- Testing
- Transcutaneous spinal cord stimulation
- Volunteers
- 5 people
- Sponsor
- Nova Scotia Health Authority
Recurrent Prostate Cancer, Stage IV Prostate Cancer
Intensive Diet and Exercise or Standard of Care in Improving Physical Function and Quality of Life in Patients With Prostate Cancer Undergoing Androgen Deprivation Therapy
This randomized pilot clinical trial studies intensive diet and exercise or standard of care in improving physical function and quality of life in patients with prostate cancer undergoing androgen deprivation therapy.
- Trial name
- IDEA-P (NCT02050906)
- Testing
- behavioral dietary intervention, exercise intervention, behavioral activity counseling
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Asthma
A Pilot and Feasibility Study of Mobile-Based Asthma Action Plans
Investigators from University of Arkansas for Medical Sciences Department of Pediatrics and University of Arkansas for Medical Sciences Center for Distance Health will collaborate to develop a mobile-based Asthma Action Plan…
- Trial name
- NCT01514760
- Testing
- Mobile-based Asthma Action Plan
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
HIV Infections, Histoplasmosis
A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS
To evaluate the feasibility of itraconazole as (1) primary therapy in histoplasmosis and (2) maintenance therapy after completion of primary therapy. To evaluate the effect of therapy of CNS histoplasmosis.
- Trial name
- NCT00000975
- Testing
- Itraconazole
- Where
- 12 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)