Clinical trials: Febrile Seizure
Seizures, Urticaria and Angioedema
A Safety Study For Prevenar 13 Among Chinese Children
This is an observational study based on a population-based EHR database.
- Conditions
- Seizures, Urticaria and Angioedema, Apnea, Fever
- Trial name
- NCT03656939
- Where
- China
- Volunteers
- 21,240 people
- Sponsor
- Pfizer
Febrile Convulsion, Neuroendocrine Stress Response
Neuroendocrine Response in Pediatric Febrile Seizures
Febrile seizures are the most common seizure type in early childhood and usually occur during febrile illnesses. Although most febrile seizures are benign, the biological stress response during seizures is not fully understood.
- Conditions
- Febrile Convulsion, Neuroendocrine Stress Response, Fever
- Trial name
- NCT07463222
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Aydin Adnan Menderes University
Febrile Seizure
Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures
Febrile seizures (FS) are the most common neurological disorder in chilhood. The etiology of FN is still the subject of numerous studies and it is known that it can depend on genetic predisposition.
- Trial name
- NCT04368936
- Testing
- Isolated DNA, Real Time PCR
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Institut za Rehabilitaciju Sokobanjska Beograd
Febrile Convulsions
The Relevance of Performing Lumbar Puncture in Infants Aged 3 to 12 Months With First Episode of Febrile Convulsion
The actual recommendations for infants aged 3 to 12 months presented with first episode of Febrile Convulsions highly recommend performing lumbar puncture in order to rule out Bacterial Meningitis.
- Trial name
- NCT01443611
- Where
- Israel
- Volunteers
- 122 people
- Sponsor
- HaEmek Medical Center, Israel
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Infants Likely to Present Febrile Convulsions
METHORIVAC - Vaccinal Pharmacoepidemiologic
This project is the pilot step necessary to develop a system of vaccination pharmacoepidemiology that associates a sophisticated analytical approach, appropriate for this challenge and case series analysis, with the use of linked…
- Trial name
- METHORIVAC (NCT01931813)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Febrile Seizure
Carbon Dioxide (Carbogen) for the Treatment of Febrile Seizures
The aim of this clinical trail is to evaluate the efficacy of a Carbogen inhalation in patients with febrile seizures compared to a placebo-inhalation.
- Trial name
- CARDIF (NCT01370044)
- Testing
- Carbogen
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Charite University, Berlin, Germany
Dravet Syndrome (DS)
A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome
This is an open-label, single-center study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of intrathecal RC001 in patients with Dravet syndrome aged 2 to 18 years.
- Trial name
- NCT07675746
- Testing
- RC001 injection-Dose Escalation Cohort, RC001 injection-Fixed Dose Cohort
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Bronchiolitis, Gastroenteritis
Viral Respiratory and Gastrointestinal Infections in Children Under 6 Years of Age
With the use of molecular methods new viruses have been detected in respiratory and gastrointestinal tracts of both patients and asymptomatic subjects in recent years.
- Conditions
- Bronchiolitis, Gastroenteritis, Convulsion, Febrile
- Trial name
- NCT00987519
- Where
- 3 sites in Slovenia
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
CDKL5 Deficiency Disorder
Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial
The primary objective of this research is to study the efficacy and safety of daily, home-based hyperthermic baths for reducing epileptic seizures in CDKL5 Deficiency Disorder.
- Trial name
- NCT07602205
- Testing
- Home-based hyperthermic Baths
- Volunteers
- 34 people
- Sponsor
- Xuanwu Hospital, Beijing
Seizure, Febrile Seizure
Nervous System Infections Among Patients With Febrile Seizure
Few studies dealing with the risk of infectious of nervous system and the utility of lumbar puncture and of emergent neuroimaging among patients with simple febrile seizure between 3 and 11 months age and with complex seizure has…
- Conditions
- Seizure, Febrile Seizure, Meningitis, Encephalitis
- Trial name
- NCT01694524
- Where
- 7 sites in France
- Volunteers
- 1,200 people
- Sponsor
- Hôpital Armand Trousseau
Epilepsy, Febrile Seizures
Copeptin in Childhood Epilepsy
In many fields of medicine, except seizure disorders, blood biomarkers have captured an integrated part of diagnostic decision making, including copeptin, the surrogate marker of vasopressin release.
- Conditions
- Epilepsy, Febrile Seizures, Children
- Trial name
- EpiCop (NCT01884766)
- Where
- Switzerland
- Volunteers
- 340 people
- Sponsor
- University Hospital, Basel, Switzerland
Febrile Seizure
A Cross-Sectional Study of Serum Levels of Adipocytokines in Children With Febrile Seizures
Febrile seizure (FS) is a common neurological condition in children, affecting 2 - 14% of children. FS is defined as seizures occurring in a child aged from six months to five years that is accompanied by a fever (≥38°C) without…
- Trial name
- NCT04967066
- Testing
- Serum Levels of Adipocytokines
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Febrile Seizure
Value of Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Febrile seizures are one of the most common clinical diseases in pediatric neurology. It occurs between 6 months and 6 years of age and occurs in ~2-5% of children.
- Trial name
- NCT05215366
- Testing
- copeptin biomarker in children with febrile seizures
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Recurrent Febrile Convulsion
Single Dose of Clonazepam Versus Intermiittent Diazepam for Febrile Seizures Prevention
To study the efficacy and safety of single dose clonazepam compared with intermittent oral diazepam for prevention of recurrent febrile seizures in children who had three or more febrile seizures.
- Trial name
- NCT04364321
- Testing
- Clonazepam 0.5 MG, Diazepam Tablets
- Where
- Thailand
- Volunteers
- 74 people
- Sponsor
- Queen Sirikit National Institute of Child Health
Febrile Seizure
Value of Von Willebrand Factor and Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Febrile seizures are one of the most common clinical diseases in pediatric neurology. It occurs between 6 months and 6 years of age and occurs in ~2-5% of children.
- Trial name
- NCT05008458
- Testing
- von willebrand factor and copeptin
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Febrile Convulsion
Effect of Febrile Convulsion Training on Anxiety and Knowledge
The research will be conducted to determine the effect of the training given to parents/caregivers on their knowledge, attitudes, practices and anxiety towards preventing febrile seizures in children.
- Trial name
- FKT (NCT06676020)
- Testing
- Nurse-delivered structured education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uskudar University
New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
The goal of this clinical trial is to find out whether two existing medications-anakinra and tocilizumab-can effectively treat a rare and life-threatening brain condition called NORSE (New-Onset Refractory Status Epilepticus).
- Conditions
- New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus, Febrile Infection-Related Epilepsy Syndrome (FIRES)
- Trial name
- COMBAT-NORSE (NCT07281027)
- Testing
- Anakinra, Tocilizumab, Standard medical treatment
- Where
- 33 sites in United States, Canada and 5 more
- Volunteers
- 438 people
- Sponsor
- Yale University
Dravet Syndrome
A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)
WAYFINDER is a Phase 1/2 study in Australia to evaluate the safety and efficacy of ETX101 in participants with SCN1A-positive Dravet syndrome aged 6 to <84 months. The study follows an open-label, dose-escalation design.
- Trial name
- NCT06112275
- Testing
- ETX101
- Where
- Australia
- Volunteers
- 4 people
- Sponsor
- Encoded Therapeutics
Febrile Seizures
Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures
To evaluate the efficacy of oral melatonin compared to oral diazepam for prevention of recurrent simple febrile seizures.
- Trial name
- NCT03631901
- Testing
- oral melatonin, oral diazepam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University