Clinical trials: Fetal Growth
Fetal Growth Retardation
Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler
Open randomized non-inferiority controlled trial to examine the use of angiogenic factors (instead of feto-placental Doppler) for fetal growth restriction at term to reduce the rate of labor inductions, without worsening…
- Trial name
- GRAFD (NCT04502823)
- Testing
- Management based on sFlt-1/PlGF values
- Where
- 20 sites in Spain
- Volunteers
- 1,088 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Preeclampsia
Low Dose Aspirin for the Prevention of Preeclampsia
Preeclampsia is one of the three leading causes of maternal morbidity and mortality all over the world. The use of low dose aspirin has been mentioned in several studies with promising results.
- Trial name
- NCT01890005
- Testing
- Aspirin
- Where
- Panama
- Volunteers
- 476 people
- Sponsor
- Saint Thomas Hospital, Panama
Severe Intra-uterine Growth Restriction, Preterm Birth
Impact of Early and Severe Fetal Growth Restriction on Neurodevelopmental Outcomes in Preterm Infants
Very early onset intra uterine growth restriction (IUGR) affects 5-10% of pregnancies and is the second leading cause of perinatal mortality.
- Conditions
- Severe Intra-uterine Growth Restriction, Preterm Birth, Neurodevelopmental Disorders, Placental Insufficiency
- Trial name
- NCT05381272
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Fetal Growth Retardation, Low Birth Weight
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
The primary aim of the study is to evaluate the effect of fortified balanced energy and protein (BEP) supplementation vs. control (multiple micronutrient supplement, MMS) without targeting and with targeting (either by low…
- Conditions
- Fetal Growth Retardation, Low Birth Weight, Preterm Birth, Gestational Weight Gain
- Trial name
- Target-BEP (NCT05576207)
- Testing
- Balanced energy and protein supplement for pregnant women, Multiple Micronutrient Supplement for pregnant women
- Where
- Bangladesh
- Volunteers
- 3,390 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Fetal Growth Retardation
Sildenafil and Uteroplacental Perfusion
The purpose of this study is to determine whether sildenafil is effective and safe in the treatment of fetal growth restriction.
- Trial name
- NCT01107782
- Testing
- sildenafil
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia)
Analysis on the Health of Newborns in Three Hospitals, 2008-2024
The objective of this observational study is to analyze the factors associated with neonatal morbidity and mortality in three hospitals in Quito, Ecuador, from January 2008 to June 2024.
- Conditions
- Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia), Prematurity Complications, Neonatal Infections
- Trial name
- NCT06758622
- Where
- Ecuador
- Volunteers
- 40,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Pregnancy Complications
Comparing Artificial Intelligence and Standard Ultrasound Methods for Estimating Fetal Weight in Pregnancy. Patients Eligible for Inclusion Are Women With a Gestational Age Between 24-42 Weeks Undergoing a Growth Scan. The Image Data From the Scan Are Used to Calculate Fetal Weight.
The primary aim of this observational study is to compare the accuracy of two artificial intelligence (AI) models with the traditional Hadlock formula for estimating fetal weight from ultrasound scans performed in pregnant women…
- Trial name
- NCT06314178
- Where
- Denmark
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Intrauterine Growth Restriction
Intra Uterine Growth Restriction
Intrauterine growth restriction (IUGR) is associated with an increase in perinatal mortality and morbidity, as well as longer-term neurological, cognitive, cardiovascular and endocrine complications.
- Trial name
- IUGR (NCT03866863)
- Testing
- Intrauterine growth restriction (IUGR)
- Where
- France
- Volunteers
- 31,052 people
- Sponsor
- Hospices Civils de Lyon
Fetal Growth Retardation
Fetal Heart Rate Variability and Fetal Growth Restriction
There is growing evidence in the field of fetal heart rate variability revealing the fetal neurological state. Furthermore, fetal heart rate variability has shown potential as fetal surveillance in fetal growth restriction.
- Trial name
- (FGR) (NCT04288037)
- Testing
- fetal heart rate variability
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Intrauterine Growth Retardation, Low Birth Weight
Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso
Low birth weight (LBW; birth weight<2,500g) is the most important determinant of mortality and morbidity in the neonatal period.
- Trial name
- MISAME2 (NCT00909974)
- Testing
- UNIMMAP - multiple micronutrients, Food supplement enriched with multiple micronutrients
- Where
- Burkina Faso
- Volunteers
- 1,302 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Intrauterine Growth Retardation
Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation
OBJECTIVES: I. Determine if mutations in the gene encoding the insulin-like growth factor-I receptor lead to relative insulin-like growth factor-I insensitivity and produce intrauterine growth retardation in children.
- Trial name
- NCT00005105
- Where
- 5 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Center for Research Resources (NCRR)
Speckle Tracking, Fetus Fetus
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using pulsed wave Doppler, Tissue Doppler and speckle tracking (strain and strain rate) between foetuses/neonates with a structural heart disease…
- Conditions
- Speckle Tracking, Fetus Fetus, Neonate, Structural Heart Disease
- Trial name
- STIPP (NCT05601375)
- Testing
- Echocardiography
- Where
- Netherlands
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Fetal Growth Retardation
Fetal Heart Rate Variability
Need statement a new way to distinguish between a healthy small fetus and a small fetus suffering from deprivation of nutrition and oxygen to prevent unnecessary induction of preterm birth and improve neonatal outcome.
- Trial name
- NCT04323865
- Testing
- fetal heart rate variability
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fetal Growth Retardation
Fetal Growth Restriction: Management Using Two Guidelines - Fetal Growth Antenatal Management Evaluation
The purpose of this study is to compare the composite neonatal adverse outcomes (CNAO) among pregnancies complicated by fetal growth restriction (FGR) managed using the Society of Maternal-Fetal Medicine (SMFM) versus…
- Trial name
- FAME (NCT05938829)
- Testing
- Ultrasound following the SMFM guidelines, Ultrasound following the ISUOG guidelines
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Intrauterine Growth Restriction
Prediction of Low Birth Weight Infants Using Ultrasound Measurement of Placental Diameter and Thickness
Prediction of Low Birth Weight Infants using Ultrasound Measurement of Placental Diameter and Thickness
- Trial name
- NCT01501851
- Where
- Egypt
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Intra-uterine Growth Restriction
Sonographic Differences in Brain Measurements Between Normal and Intrauterine Growth Restriction (IUGR) Fetuses
Intrauterine growth restriction is being suspected in cases where the fetal estimated weight is less then the 10 th percentile for its gestational age. Abdominal circumference is the most influenced measurement in this cases.
- Trial name
- NCT01178619
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center