Clinical trials: Fetus Fetus
Induction of Labor Affected Fetus / Newborn
Dexamethasone and Induction of Delivery
This study aims to evaluate the effect of intravenous injection of a single dose of dexamethasone in shortening the duration interval between initiation of labor induction and delivery of the fetus in primigravida full-term…
- Trial name
- NCT03658590
- Testing
- Dexamethasone, Distilled Water
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- samar sayed el sayed
Induction of Labor Affected Fetus / Newborn
Dilapan-S® for Induction of Labor The Feasibility Study
This is a prospective feasibility study to investigate Dilapan-S® as an outpatient method of cervical ripening in low risk pregnancies >=39 weeks.
- Trial name
- DILATE (NCT04521062)
- Testing
- Dilapan S
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Thromboelastography, Coagulation; Fetus or Newborn
Thromboelastographic Profile in Healthy Newborns and Infants of Diabetic Mothers Using TEG6s
Thromboelastography (TEG) is a laboratory technique used to examine the process of clot formation and degradation by measuring and reporting the kinetic changes, the rate of clot formation, clot strength, and clot stability.
- Conditions
- Thromboelastography, Coagulation; Fetus or Newborn, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NCT04917965
- Testing
- Laboratory clotting studies
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Speckle Tracking, Fetus Fetus
Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Comparison of prenatal and postnatal cardiac function assessed by echocardiography using pulsed wave Doppler, Tissue Doppler and speckle tracking (strain and strain rate) between foetuses/neonates with a structural heart disease…
- Conditions
- Speckle Tracking, Fetus Fetus, Neonate, Structural Heart Disease
- Trial name
- STIPP (NCT05601375)
- Testing
- Echocardiography
- Where
- Netherlands
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Fetal Developmental Abnormality, Fetal Development
Scottish Advanced Fetal Research Study
In-utero exposure to drugs and chemicals through maternal smoking, alcohol use, drug abuse, prescription medicines and occupational/lifestyle exposures is widespread.
- Conditions
- Fetal Developmental Abnormality, Fetal Development, Human, Life Style
- Trial name
- SAFeR (NCT04613583)
- Testing
- SAFeR fetuses
- Where
- United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Prematurity of Fetus
Pharmacokinetics of Oseltamivir in Newborns and Infants
Oseltamivir dosing in infants < 3 months of age is based on a single pharmacokinetic study in 20 infants from a single center. This dataset is limited by a lack of robustness, because only 1 sample was collected from each…
- Trial name
- NCT01388439
- Testing
- Oseltamivir
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- St. Louis Children's Hospital
Medical; Abortion, Fetus
Simplified Medical Abortion Screening: A Pilot Demonstration Project
This study aims to collection additional data on the safety and acceptability of medical abortion without pretreatment pelvic ultrasound or exam in woman who meet certain criteria.
- Trial name
- NCT02381223
- Where
- 5 sites in United States, Mexico and 1 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation
The purpose of this study is to determine the efficacy and acceptability of a regimen of 200 mg mifepristone (Zacafemyl), followed 24-48 hours later by 800 mcg of buccal misoprostol.
- Trial name
- NCT01966874
- Where
- United States
- Volunteers
- 1,001 people
- Sponsor
- Gynuity Health Projects
Chromosome Disorders
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and…
- Trial name
- NCT00064597
- Where
- 5 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Renal Failure Congenital, Congenital Renal Anomaly Nos
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Congenital lower urinary tract obstruction (LUTO) is a heterogeneous group of congenital anomalies that lead bladder outlet obstruction.
- Conditions
- Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
- Trial name
- NCT03723564
- Testing
- Lactated Ringers Solution for Injection
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Medical; Abortion, Fetus
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone
Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy
- Trial name
- NCT05940233
- Testing
- Letrozole
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Induction of Labor Affected Fetus / Newborn
Nitroglycerin Skin Patches for Facilitating Cervical Ripening: A Randomized Controlled Trial
This study aims to establish the efficacy of transdermal glyceryl trinitrate as a nitric oxide donor in addition to dinoprostone for induction of cervical ripening in the third trimester through progression in the Bishop's score…
- Trial name
- NCT03320187
- Testing
- Nitroderm TTS, Dinoprostone
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Prematurity of Fetus
LACTACOL 01 - Impact of Breast Milk on the Neurodevelopment of Preterm Newborns
The aim of the study is to estimate the impact of the protein content of breastmilk at the end of hospitalization of the preterm newborn, on the neurodevelopment at 2 years old.
- Trial name
- NCT01493063
- Testing
- Physiopathology
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Nantes University Hospital
Cord Blood Amino Acid Profile, Fetal Amino Acid Profile in Different Gestational Ages
Amino Acid Profile in the Fetus and the Neonate
Up-to-date, the preterm newborn nutrition is based on human breast milk or it's imitations. However, the growth rate is known to be reduced compared to the fetal growth rate.
- Conditions
- Cord Blood Amino Acid Profile, Fetal Amino Acid Profile in Different Gestational Ages, Infant Amino Acid Profile at Day 3 and Discharge
- Trial name
- NCT01140698
- Testing
- Blood sample on Guthrie paper from cord blood, and day 3 of life and before discharge
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention
All factors that influence the peak bone mass achieved at skeletal maturity are important in determining an individual's risk of developing osteoporosis later in life.
- Conditions
- Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal Population
- Trial name
- REMS-BONE (NCT06750523)
- Testing
- Cord blood sampling, urine sampling, Life style questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Parma
Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn
Amniotic Fluid & the Preterm Gut
Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.
- Conditions
- Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn, Necrotizing Enterocolitis of Newborn, Neonatal Sepsis, Early-Onset
- Trial name
- AMFIBIE (NCT07152106)
- Where
- 2 sites in Netherlands
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Zika Virus Infection on Fetus and Child During the Pregnancy
Zika Virus Infection's Neonatal and Pediatric Consequences in French Department of America
The Zika epidemic has spread into the three French Overseas Departments in the Caribbean (DFAs). It is therefore urgent to set up tools to collect clinical and paraclinical data for the evaluation of potential complications due…
- Trial name
- ZIKA-DFA-BB (NCT02810210)
- Testing
- fundus examination, Head ultrasound
- Where
- 6 sites in France, French Guiana and 2 more
- Volunteers
- 1,180 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Induction of Labor Affected Fetus / Newborn, Prostaglandins Causing Adverse Effects in Therapeutic Use
Induction of Labor in Term Pregnancies With Unfavourable Cervix
This is a prospective randomized trial comparing two prostaglandin E2 (dinoprostone) agents used for labor induction in pregnant women with term pregnancies and unfavorable cervix.
- Trial name
- RAND (NCT04280874)
- Testing
- Dinoprostone 0.5 MG, Dinoprostone 2 MG/2.5 ML Vaginal Gel/Jelly
- Where
- Croatia
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Merkur
Maternal; Chorioamnionitis, Affecting Fetus, Early-Onset Sepses, Neonatal
A Chart Review of Newborns With the Presence of Confirmed or Suspected Maternal Chorioamnionitis and Utilization of the Early Onset Sepsis Calculator
This study will review practices in relation to chorioamnionitis (CAM) before and after to the implementation of the Neonatal Early-Onset Sepsis (EOS) Risk Calculator to determine the effect in the nursery at Banner - University…
- Trial name
- NCT04513691
- Testing
- EOS Calculator
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Pediatrix
Breech Presentation
Moxibustion for Fetus in Breech Presentation
Objective: To evaluate moxibustion of the BL67 acupoint between 34 and 38 weeks of gestation to facilitate cephalic version of breech presentation in a Western setting.
- Trial name
- NCT00890474
- Testing
- Moxibustion of the BL67 acupoint
- Where
- Switzerland
- Volunteers
- 212 people
- Sponsor
- University Hospital, Geneva