Clinical trials: Fetus Fetus
Congenital Heart Disease, Disorder of Fetus or Newborn
Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Randomized controlled trial of the use of glucocorticoids to improve the clinical course of neonates post-cardiopulmonary bypass (CPB).
- Trial name
- NCT00934843
- Testing
- methylprednisolone (IVMP), methylprednisolone (two doses IVMP)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Medical University of South Carolina
Multiple Anomalies of Fetus, Genetic Predisposition Suspected
AMNIOmics: A Prenatal Rapid Genome Validation Study
The purpose of this study is to validate Whole Genome Sequencing (WGS) on amniotic fluid to reduce the time to diagnosis and enhance the care for the fetus/neonate.
- Conditions
- Multiple Anomalies of Fetus, Genetic Predisposition Suspected, Amniocentesis Affecting Fetus or Newborn, Family Members
- Trial name
- NCT05834621
- Sponsor
- Mayo Clinic
Erythroblastosis, Fetal, Erythroblastosis Fetalis, Rh Disease
EPO-4-Rhesus Study
Up to 80% of infants with hemolytic disease due to maternal alloimmunization, treated with IUT, require at least one top-up transfusion for late anemia during the first 3 months of life.
- Conditions
- Erythroblastosis, Fetal, Erythroblastosis Fetalis, Rh Disease, Erythroblastosis Fetalis Due to RH Antibodies, Erythroblastosis Fetalis Due to Isoimmunization
- Trial name
- EPO-4-Rhesus (NCT03104426)
- Testing
- Darbepoetin Alfa
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Virtual Reality, Induction of Labor Affected Fetus / Newborn
VR Glasses During Induction of Labour for Pain and Anxiety Relieve
In the current study, The investigators aim is to test the distraction affect of "Virtual Reality" (VR) technology on pain and anxiety in pregnant women who undergo through an induction of labour with an extra-amniotic balloon…
- Conditions
- Virtual Reality, Induction of Labor Affected Fetus / Newborn, Extra Amniotic Balloon
- Trial name
- NCT05187247
- Testing
- Virtual Reality glasses
- Where
- Israel
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Suspected Damage to Fetus From Biologic Agents
Study on the Safety for the Newborn of the Use of Biologics During Pregnancy by Mothers Affected by Autoimmune Diseases
The goal of the study is to evaluate the effects on the offspring and therefore the safety of using biologic agents during pregnancy and their eventual consequences on children.
- Trial name
- BIOGN1 (NCT04197232)
- Testing
- clinical evaluation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele
Pregnancy
Effects of Dairy Foods on Adolescent Pregnant Mothers and Their Newborns
The purpose of the study is to evaluate the effects of different dietary calcium have on the pregnant teen mother and her newborn.
- Trial name
- NCT00320125
- Testing
- Orange juice plus calcium, Dairy products
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Induction of Labor Affected Fetus / Newborn
Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity increases the risk of pregnancy complications, including among others puerperal infections and cesarean delivery, and risk rises with increasing body mass index (BMI).
- Trial name
- APPOINT (NCT03801252)
- Testing
- Cefazolin, Azithromycin
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pregnancy Related
Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation
The participants of this study will be of any age who are exposed to at least 1 dose of odevixibat at any time during pregnancy (from 1 day prior to conception to pregnancy outcome) and/or at any time during lactation (up to 12…
- Trial name
- NCT06258902
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ipsen
Uterine Contractions; Prolonged, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
A Home Telemonitoring System for Wearable Fetal-ECG and EHG Acquisition During Pregnancy
The goal of this observational is to compare in describing fetal health conditions. The main questions it aims to answer are: fetal electrocardiogram (fetal heart rate and fetal rhythm) electrohysterography (uterine…
- Conditions
- Uterine Contractions; Prolonged, Fetal Heart Rate or Rhythm Abnormality Affecting Fetus, Pregnancy Related, Home Range
- Trial name
- AHTSWFEADP (NCT06031142)
- Testing
- use wearable devices to monitoring fetal health conditions.
- Where
- China
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Fudan University
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Newborn Cleft Lip and Slot Carrier
Biochemical and Histological Comparison of Nasal and Auricular Cartilage in the Fetus and Newborn With Cleft Lip Carrier
We seek to compare biochemically and histologically the nasal cartilage and ear in the newborn cleft lip and slot carrier in order to improve the quality of care and patient comfort after surgery of cheilorhinoplasty which is the…
- Trial name
- CARTOON (NCT02505360)
- Testing
- Measurements of concentration of hyaluronic acid as well as in type 1 collagen and 3
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Nephropathy
Amniotic Biomarkers for the Prediction of Postpartum Renal Function.
The discovery of antenatal bilateral renal anomaly poses an essential question: can we predict postnatal renal function? Ultrasound is insufficiently precise to predict postnatal renal function evolution.
- Trial name
- BIOMAN (NCT02675686)
- Where
- 31 sites in France
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Zika Virus Infection on Fetus and Child During the Pregnancy
Zika Virus Infection's Neonatal and Pediatric Consequences in French Department of America
The Zika epidemic has spread into the three French Overseas Departments in the Caribbean (DFAs). It is therefore urgent to set up tools to collect clinical and paraclinical data for the evaluation of potential complications due…
- Trial name
- ZIKA-DFA-BB (NCT02810210)
- Testing
- fundus examination, Head ultrasound
- Where
- 6 sites in France, French Guiana and 2 more
- Volunteers
- 1,180 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Medical; Abortion, Fetus
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation
The purpose of this study is to determine the efficacy and acceptability of a regimen of 200 mg mifepristone (Zacafemyl), followed 24-48 hours later by 800 mcg of buccal misoprostol.
- Trial name
- NCT01966874
- Where
- United States
- Volunteers
- 1,001 people
- Sponsor
- Gynuity Health Projects
Placental Insufficiency Hypertensive Disorders of Pregnancy Diabetes Mellitus in Pregnancy Thrombophilia in Pregnancy Adverse Perinatal Outcomes
Fetus Programming and Long Active Outcomes, Interaction Between Mother, Placenta and Fetus in Perinatal and Methabolic Disbalansces-focusing Diabetic Pregnancies
The placenta is a temporary but essential organ that develops during pregnancy and supports the growth and survival of the fetus.
- Trial name
- NCT07337759
- Testing
- No intervention (observational study)
- Where
- Serbia
- Volunteers
- 440 people
- Sponsor
- University of Belgrade
Medical; Abortion, Fetus
Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina Faso
The goal of this study is to examine the effectiveness and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Burkina Faso.
- Trial name
- NCT03269279
- Testing
- Mifepristone, Misoprostol
- Where
- 4 sites in Burkina Faso
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Dengue, Pregnancy Preterm
Materno-fetal Consequences of Symptomatic Dengue in Pregnant Wowen in French Guiana
Symptomatic dengue virus infection in pregnant women could affect the mother, fetus and the newborn at birth. The risks of postpartum hemorrhage, prematurity and low birth weight are increased in dengue fever.
- Conditions
- Dengue, Pregnancy Preterm, Women, Fever
- Trial name
- CMFdeng (NCT04989673)
- Testing
- Biological sampling and collection (serum), Biological sampling and collection (placenta), Questionnaire
- Where
- French Guiana
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Hirschsprung Disease, Bowel; Perforation, Fetus or Newborn
Risk Factors of Perforated HSCR in Neonates
Hirschsprung's disease (HSCR) is a common digestive malformation with radiographic evidence of distal bowel obstruction and clinical signs of abdominal distension, vomiting, constipation, and failure to pass meconium.
- Trial name
- NCT05044741
- Testing
- Emergency surgical enterostomy
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital
Congenital Anomalies, Neonatal Complications
AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes
This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans.
- Conditions
- Congenital Anomalies, Neonatal Complications, Perinatal Outcomes, Perinatal Outcomes of the Mother and Fetus
- Trial name
- NCT07064356
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- FetalFirst Limited
Friedreich Ataxia
A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies
In this study, researchers will learn more about the safety of BIIB141, also known as omaveloxolone or SKYCLARYS. This is a drug available for doctors to prescribe for people with Friedrich's Ataxia, also known as FA.
- Trial name
- NCT06628687
- Testing
- Omaveloxolone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Biogen