Clinical trials: Fibrillation, Atrial
Atrial Fibrillation
Amplify EP Registry
An observational, prospective, multi-center, non-randomized registry designed to obtain real world clinical experience with the TactiFlex Catheter Ablation system in the treatment of Atrial Fibrillation.
- Trial name
- AMP (NCT06669637)
- Testing
- Ablation
- Volunteers
- 1,100 people
- Sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
Mitral Valve Insufficiency, Atrial Fibrillation
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function.
- Conditions
- Mitral Valve Insufficiency, Atrial Fibrillation, Heart Failure
- Trial name
- NCT01172184
- Testing
- Cardiac catheterization
- Where
- Taiwan
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Atrial Fibrillation, Surgery--Complications
Incidence of Post-operative Atrial Fibrillation Secondary to Abdominal Surgery
Background and purpose Post-operative AF (POAF) is considered a phenomenon rather than a definite diagnosis and the current clinical guidelines have no specific recommendations regarding its management.
- Trial name
- SECAFIB-SURG (NCT04090905)
- Testing
- Standard clinical monitoring, Holter monitoring
- Where
- Denmark
- Volunteers
- 466 people
- Sponsor
- Frederiksberg University Hospital
Atrial Fibrillation
Non Invasive Mapping Before Ablation for Atrial Fibrillation.
RATIONALE / CONTEXT The ECG records the electrical activity propagating along cardiac cells (from the atria to the ventricles). The standard 12 ECG leads placed on the chest measure the global activation of the heart and do not…
- Trial name
- AFACART (NCT02113761)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Persistent Atrial Fibrillation, Persistent Atrial Fibrillation Longstanding
Catheter Ablation of Advanced Forms of Atrial Fibrillation
The purpose of this study is to evaluate feasibility, safety, and efficacy of pulmonary vein isolation combined with posterior left atrial isolation and multiple linear lesions in both atria in patients with persistent and…
- Trial name
- ENDO MAZE (NCT07446244)
- Testing
- Endovascular ablation set mimicking cox maze 4 procedure.
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Blood Pressure, Depression
Essential Hypotension and Allostasis Registry
The essential arterial hypotension and allostasis registry is a prospective, observational research that has the purpose of demonstrating that essential blood pressure (BP) disorders and the associated comorbidities are a result…
- Conditions
- Blood Pressure, Depression, Panic Attack, Fibromyalgia
- Trial name
- ESSENTIAL (NCT02018497)
- Where
- Colombia
- Volunteers
- 5,000 people
- Sponsor
- CES University
Atrial Fibrillation
Manual Compared to Magnetic Navigation in Ablation for Atrial Fibrillation
The purpose of this study is to compare manual and magnetic navigation in ablation for atrial fibrillation.
- Trial name
- NCT01407588
- Testing
- Magnetic navigation, Ablation performed with manual navigation
- Where
- Norway
- Volunteers
- 51 people
- Sponsor
- Norwegian University of Science and Technology
Atrial Fibrillation
Prediction and Maintenance of Sinus Rhythm Among Atrial Fibrillation Patients
Atrial fibrillation (AF) is the most common heart rhythm disorder seen in clinical practice, with an estimated 2.7-6.1 million people in the U.S. affected by the disorder [1].
- Trial name
- NCT04313296
- Testing
- Unique measurement (AutoSTRAIN) by a commercial software program (TOMTEC-ARENA)
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Crystal Blake-Parlin
Atrial Fibrillation
Safe Use of New Oral Anticoagulants in Ablation for Atrial Fibrillation
Use of new oral anticoagulants (NOAC) in patients before and after catheter based pulmonary vein isolation (PVI) is still controversial.
- Trial name
- NCT02569255
- Testing
- Pulmonary venous ostia isolation
- Volunteers
- 234 people
- Sponsor
- Private Hospital Heart Center Varde
Cardiac Magnetic Resonance, Extracellular Volume Overload
Extracellular Volume Associated With New-Onset Atrial Fibrillation
Left ventricular fibrosis is strongly associated with atrial fibrillation (AF). However, the relationship between LV fibrosis and new-onset AF (NOAF) after ST-segment elevation myocardial infarction (STEMI) is currently unknown.
- Conditions
- Cardiac Magnetic Resonance, Extracellular Volume Overload, Myocardial Infarction, Atrial Fibrillation
- Trial name
- NCT06447857
- Testing
- Cardiac MRI
- Where
- China
- Volunteers
- 589 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Atrial Fibrillation, Bradycardia
Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA Class
This registry is a data collection on patients who are implanted for more than 6 months with a pacemaker. Frequency and distribution of right ventricular pacing, NYHA class and left ventricular ejection fraction shall be…
- Conditions
- Atrial Fibrillation, Bradycardia, Heart Block, Sick Sinus Syndrome
- Trial name
- NCT00292539
- Testing
- Any pacemaker with right ventricular pacing option
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Guidant Corporation
Atrial Fibrillation
Evaluation of Potential Off-label Use of Dabigatran Etexilate in Europe
This is a descriptive, observational, multi-country European cross-sectional study of new users of dabigatran etexilate that aims to characterise on- and off-label status and other medical characteristics at the time of the first…
- Trial name
- NCT02240654
- Where
- Spain
- Volunteers
- 36,573 people
- Sponsor
- Boehringer Ingelheim
Atrial Fibrillation
Atrial Fibrillation After Cardiac Surgery-comparing Conventional and Miniaturized Bypass Systems
Atrial fibrillation (AF) is the most common arrhythmia after cardiac surgery. The incidence of AF varies between 20 - 45 % after (coronary artery bypass grafting) CABG.
- Trial name
- NCT01160393
- Testing
- Miniaturized bypass system
- Where
- Finland
- Volunteers
- 240 people
- Sponsor
- Kuopio University Hospital
Stroke
Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation
Title: Optimal Delay Time to Initiate Anticoagulation after Ischemic Stroke in Atrial Fibrillation (START): a pragmatic, adaptive randomized clinical trial.
- Trial name
- START (NCT03021928)
- Testing
- Time-To-Treatment Randomization
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Texas at Austin
Acute Coronary Syndrome, Atrial Fibrillation
Short- and Long-term Health Effects of Air Pollution in Poland
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack…
- Conditions
- Acute Coronary Syndrome, Atrial Fibrillation, Kidney Diseases, Particulate Matter Inhalation Injury
- Trial name
- EP-PARTICLES (NCT05198492)
- Testing
- Impact of air pollution
- Where
- Poland
- Volunteers
- 8,300,000 people
- Sponsor
- Medical University of Bialystok
Atrial Fibrillation
Study on Left Atrial Function of Atrial Fibrillation After Radiofrequency Ablation With Statin Therapy
A total of 120 patients with persistent atrial fibrillation (including continuous and long-standing persistent atrial fibrillation) and 60 patients with paroxysmal atrial fibrillation will receive radiofrequency ablation.
- Trial name
- NCT02776956
- Testing
- atorvastatin group, non-atorvastatin group
- Where
- China
- Volunteers
- 180 people
- Sponsor
- xieruiqin
Atrial Fibrillation
Change of Heart Rate Variability and Baroreflex Sensitivity After Ventral Cardiac Denervation
Atrial fibrillation (Af) is the most common morbid event after open heart surgery. Its incidence ranges from 19% to 27%, as reported by the Society of Thoracic Surgeons database.
- Trial name
- NCT00190112
- Testing
- ventral cardiac denervation
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Stroke, Atrial Fibrillation
Novel Methods for Arrhythmia Detection: Preliminary Study
Approximately 20-25% of strokes are of cardioembolic origin, atrial fibrillation (AF) being a significant cause of cardioembolic strokes. AF is often symptomless and intermittent, making its detection a clinical challenge.
- Trial name
- NCT03721601
- Testing
- Heart rate monitor chest strap, Wrist band photoplethysmography
- Where
- 3 sites in Finland
- Volunteers
- 220 people
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation
RedStroke - Reducing Europe's Stroke Incidence
In the RedStroke study, the effect of a smartphone application in detecting Atrial Fibrillation (AF) will be assessed in a double-blind randomised controlled multicenter trial.
- Trial name
- RedStroke (NCT04108884)
- Testing
- App measurement, 14 day Holter ECG
- Where
- 7 sites in Germany, Greece and 4 more
- Volunteers
- 1,019 people
- Sponsor
- University Hospital, Basel, Switzerland