Clinical trials: Flu Like Illness
Novel Influenza A (H1N1), A New Flu Virus of Swine Origin
Observational Study of Safety of Flu Cell Culture Derived Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Vaccine
This is an observational study of safety and occurrence of influenza-like illness following administration of flu cell culture derived adjuvanted swine origin A (H1N1) pandemic subunit vaccine in subjects 6 months of age and…
- Trial name
- NCT01037855
- Testing
- Non-intervention observational study
- Where
- 10 sites in Chile, Colombia and 2 more
- Volunteers
- 4,028 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza-like Illness, Upper Respiratory Disease
Non-specific Effects of Rabies Vaccine
Vaccines work by stimulating the body to produce a high-quality, rapid and specific immune response upon exposure to infection by a particular disease-causing microorganism - the microorganism targeted by the vaccine.
- Conditions
- Influenza-like Illness, Upper Respiratory Disease, Diarrhea, Fever
- Trial name
- NCT03656198
- Testing
- Rabivax-S, Sterile Water Injection
- Where
- Saint Kitts and Nevis
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Ross University School of Veterinary Medicine
Malaria, Dengue
Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal
This trial aims to validate a novel clinical care strategy based on a electronic clinical decision support algorithm (CDSA) combined with point of care rapid diagnostic tests by evaluating its impact on antibiotic prescription…
- Conditions
- Malaria, Dengue, Influenza -Like Illness, Diarrhea
- Trial name
- NCT05050825
- Testing
- Patient clinical management based on the CDSA strategy
- Where
- 4 sites in Senegal
- Volunteers
- 470 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Influenza, Acute Respiratory Infection
FluSAFE: Flu SMS Alerts to Freeze Exposure
Influenza infection results in an estimated 31 million outpatient visits, 55,000 to 974,200 hospitalizations, and 3,000 to 49,000 deaths.
- Conditions
- Influenza, Acute Respiratory Infection, Influenza-like Illness
- Trial name
- NCT03274310
- Testing
- Educational text messages
- Where
- United States
- Volunteers
- 1,918 people, healthy volunteers welcome
- Sponsor
- Columbia University
Influenza
Acute Respiratory Infection Consortium
Recently, the emergence and rapid global dissemination of novel swine-origin influenza A virus (H1N1) with unique epidemiologic characteristics has heightened awareness and concern of this viral pathogen, and its potential for…
- Trial name
- ARIC (NCT01021098)
- Where
- 5 sites in United States
- Volunteers
- 2,018 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Influenza Like Illness, Asthma
How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment.
- Conditions
- Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
- Trial name
- WGA (NCT01979588)
- Testing
- What's Going Around tool, Control
- Where
- United States
- Volunteers
- 206,703 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Influenza, Pneumonia
Oseltamivir Randomised Controlled Efficacy Trial
Background In preparation for a global influenza pandemic, there is an urgent need for representative data from populations and settings where the pandemic is most likely to arise.
- Conditions
- Influenza, Pneumonia, Lower Respiratory Tract Infection, Upper Respiratory Tract Infection
- Trial name
- NCT00707941
- Testing
- Oseltamivir
- Where
- Bangladesh
- Volunteers
- 1,190 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Influenza Virus Infection, Influenza-like Illness
Direct and Indirect Benefits of Influenza Vaccination in Schools and Households
The purpose of this study is to determine the degree of indirect benefits to family members and classmates resulting from administration of influenza vaccine to children.
- Conditions
- Influenza Virus Infection, Influenza-like Illness, Acute Respiratory Infection
- Trial name
- NCT00981513
- Testing
- Trivalent live attenuated seasonal influenza vaccine, Monovalent live attenuated pandemic influenza vaccine, Saline
- Where
- Hong Kong
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acute Respiratory Infection, Influenza-like Illness
Effectiveness and Implementation of a National Guideline for Acute Respiratory Tract Infections to Reduce Antibiotic Prescribing in Swiss Primary Care
The ImpProGUIDE study aims to find out whether implementing new Swiss national guidelines for acute respiratory infections (ARI) can help to reduce antibiotic prescribing in primary care.
- Trial name
- ImpProGUIDE (NCT07396428)
- Testing
- Training Session on acute respiratory infection guideline within a multifaceted implementation strategy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Influenza -Like Illness, Influenza (Healthy Volunteers)
Mucosal and Systemic Immunity Correlates of Protection Against Influenza in Young Children, Aged 2-5 Years (MUSIC-Flu)
Title: Mucosal and systemic immunity correlates of protection against influenza in young children (MUSIC-Flu). The goal of this observational study is to better understand how immune responses in the blood and mucosa are linked…
- Trial name
- MUSIC-Flu (NCT07861854)
- Where
- South Africa
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
COVID-19, Pneumonia, Viral
Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X-Rays
This project aims to use artificial intelligence (image discrimination) algorithms, specifically convolutional neural networks (CNNs) for scanning chest radiographs in the emergency department (triage) in patients with suspected…
- Conditions
- COVID-19, Pneumonia, Viral, Influenza With Pneumonia, Flu Symptom
- Trial name
- AI-COVID-Xr (NCT04313946)
- Testing
- Scanning Chest X-rays and performing AI algorithms on images
- Where
- 3 sites in Italy, Romania and 1 more
- Volunteers
- 200 people
- Sponsor
- Professor Adrian Covic
Influenza, Influenza -Like Illness
Broadening Our Understanding of Early Versus Late Influenza Vaccine Effectiveness
This study uses a prospective cohort design to investigate if the seasonal influenza vaccine is equally effective when given early and late before the proceeding influenza season.
- Trial name
- BELIEVE (NCT04570904)
- Testing
- Influenza vaccination at different time points
- Where
- United Kingdom
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Leicester
COVID-19 Respiratory Infection, Respiratory Virus Infection
Preventing Respiratory Viral Illness Invisibly
Elderly people who have multiple health problems are at higher risk of illness from viral respiratory infections, such as influenza (the flu) and COVID-19.
- Conditions
- COVID-19 Respiratory Infection, Respiratory Virus Infection, Influenza -Like Illness
- Trial name
- PRiVII (NCT05084898)
- Testing
- Far-UVC light as an additional method of disinfection
- Where
- 3 sites in Canada
- Volunteers
- 550 people
- Sponsor
- Kenneth Rockwood
Acute Respiratory Infection, Influenza-like Illness
ORCHARDS-AIR Study
The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air.
- Trial name
- NCT07298967
- Testing
- Nasal swab, Indoor air quality monitor
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- University of Wisconsin, Madison
Respiratory Tract Infections (RTI), Influenza-like Illness
Clinical Assessment of Respiratory Events for Kids: Integrating Diagnostics and Stewardship
This study, called Care4Kids, aims to improve the management of respiratory infections in children visiting emergency departments.
- Conditions
- Respiratory Tract Infections (RTI), Influenza-like Illness, Children
- Trial name
- CARE4KIDS (NCT07453914)
- Testing
- SPOTFIRE R
- Where
- 3 sites in France, Greece and 1 more
- Volunteers
- 720 people
- Sponsor
- BioMérieux
Influenza, Influenza Like Illness
Seasonal Influenza Vaccine Effectiveness Study in Kenya
Influenza is an important cause of acute respiratory infections (ARI) worldwide. Seasonal influenza causes an estimated 250,000-500,000 deaths and 3-5 million severe illnesses each year (WHO, 2009), and pandemic 2009 H1N1…
- Conditions
- Influenza, Influenza Like Illness, Severe Acute Respiratory Illness
- Trial name
- NCT01432340
- Testing
- Seasonal influenza vaccine
- Where
- 2 sites in Kenya
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Gideon Emukule
Influenza -Like Illness, Covid19
Epidemiological Investigation of COVID-19 in Laos Using a One-Health Approach in Human and Animals
The Respiratory infection COVID-19, due to a new coronavirus, SARS-CoV2, appeared in December 2019 in several people who attended the wildlife market in Wuhan, Hubei Province, China.
- Trial name
- LACOVISS (NCT04716543)
- Testing
- ILI and COVID-19 detection
- Volunteers
- 5,400 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Respiratory Tract Infections (RTI), Influenza -Like Illness
Virological Surveillance of Acute Respiratory Infection in Primary Health Care in Metropolitan France
Every year in the fall and winter, numerous respiratory viruses (such as influenza viruses, SARS-CoV-2 (COVID-19), RSV, rhinovirus, and metapneumovirus) circulate in mainland France, causing acute respiratory infections (ARIs).
- Conditions
- Respiratory Tract Infections (RTI), Influenza -Like Illness, Influenza, COVID - 19
- Trial name
- RS-viro IRA (NCT07599449)
- Testing
- saliva sampling, Nasopharyngeal swab
- Where
- France
- Volunteers
- 25,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pandemic Influenza A (H1N1), A New Flu Virus of Swine Origin
Observational Safety Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine
This is an observational safety study of a prophylactic use of Flu Egg Derived Adjuvanted Swine Origin A(H1N1) Vaccine in subjects 6 months of age and older.
- Trial name
- NCT01040741
- Testing
- Non-intervention observational study
- Where
- 14 sites in Argentina, Netherlands
- Volunteers
- 7,284 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza-like Illness
Characterization of Influenza-like Illness in Mexico
A study to characterize children and adults with influenza like symptoms and to determine risk factors for severe disease and death among those with H1N1.
- Trial name
- NCT01418287
- Where
- 6 sites in Mexico
- Volunteers
- 5,819 people
- Sponsor
- Mexican Emerging Infectious Diseases Clinical Research Network