Clinical trials: Fluconazole
Candidiasis
Fluconazole Versus Micafungin in Neonates With Candidiasis
This study is designed to determine whether micafungin is as efficacious as the current standard of fluconazole, to compare the safety of the two drugs in the treatment of proven neonatal candidiasis.
- Trial name
- TINN (NCT02145832)
- Testing
- Fluconazole, Micafungin
- Where
- 5 sites in Belgium, France and 3 more
- Volunteers
- 100 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Candidiasis, Oral
Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis
To determine the efficacy and safety of IV Micafungin versus IV Fluconazole in the treatment of patients with Esophageal Candidiasis
- Trial name
- NCT00666185
- Testing
- Micafungin, Fluconazole
- Where
- 37 sites in Brazil, Peru and 1 more
- Volunteers
- 523 people
- Sponsor
- Astellas Pharma Inc
Candida, Candidiasis
Anidulafungin Versus Fluconazole in the Treatment of Candidemia
Fluconazole is an FDA-approved drug that is widely used to treat fungal infections due to candida. The experimental drug anidulafungin has been found to be active in treating life-threatening fungal infections.
- Trial name
- NCT00058682
- Testing
- Anidulafungin
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- National Cancer Institute (NCI)
Very Low Birth Weight Infant
Pharmacokinetic Study of Fluconazole in Premature Infants
The purpose of this study is to investigate the pharmacokinetics of fluconazole which is used as prophylaxis of invasive fungal infection in premature infants.
- Trial name
- NCT01683760
- Testing
- Fluconazole
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Acquired Immunodeficiency Syndrome, Candidiasis
Fluconazole Prophylaxis of Thrush in AIDS
This is a placebo-controlled trial of intermittent fluconazole prophylaxis (200 mg orally three times a week) in the prevention of thrush.
- Conditions
- Acquired Immunodeficiency Syndrome, Candidiasis, Oral Candidiasis
- Trial name
- NCT00001542
- Testing
- fluconazole
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ductus Arteriosis, Patent, Bacterial Infections and Mycoses
Safety of Fluconazole Treatment of Premature and Full-term Newborn Infants
This study will investigate pharmacological interventions between fluconazole and ibuprofen when they are given to premature newborn babys.
- Trial name
- NCT02079298
- Testing
- Treatment with fluconazole., 2. Treatment with both fluconazole and Ibuprofen., 3. Treatment with ibuprofen.
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Anders Rane, MD, PhD, Senior professor
Deep Mycosis
Diflucan Research For Infant Evaluation Of Antifungal Treatment And Prophylaxis Medication
To collect the efficacy and safety information of fluconazole on infant subjects related to their appropriate use in daily practice.
- Trial name
- DREAM (NCT01680458)
- Testing
- Fluconazole
- Volunteers
- 30 people
- Sponsor
- Pfizer
Nevirapine, Fluconazole
Nevirapine Levels and Fluconazole
Nevirapine (NVP)-based antiretroviral therapy (ART) has been commonly used in many developing countries due to its affordability and feasibility.
- Conditions
- Nevirapine, Fluconazole, Adverse Event
- Trial name
- NCT00309582
- Sponsor
- Bamrasnaradura Infectious Diseases Institute
Neurodevelopmental Outcomes
Neurodevelopmental Outcomes and Fluconazole Prophylaxis
The purpose of this study is to compare the neurodevelopmental outcome and quality of life between the fluconazole-treated and the placebo-treated patients that were enrolled in a fluconazole prophylaxis study that occurred in…
- Trial name
- NDFP (NCT00975949)
- Testing
- Survey
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Virginia
Meningitis, Cryptococcal, HIV Infections
Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
The purpose of this study is to examine the antifungal activity of recombinant interferon-gamma 1b (rIFN-gamma 1b) given with standard antifungal therapy.
- Trial name
- NCT00012467
- Testing
- Itraconazole, Flucytosine, Fluconazole
- Where
- 9 sites in United States, Peru
- Volunteers
- 60 people
- Sponsor
- InterMune
Mycoses, HIV Infections
A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common
To compare the efficacy of fluconazole versus placebo in preventing the development of active coccidioidomycosis and other systemic fungal infections among HIV-infected patients with CD4 lymphocyte counts < 250 cells/mm3 who are…
- Conditions
- Mycoses, HIV Infections, Coccidioidomycosis
- Trial name
- NCT00002325
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Sponsor
- Pfizer
Acute Myeloid Leukemia, Adult Acute Monoblastic Leukemia
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia
This randomized phase III trial compares the effectiveness of caspofungin to fluconazole in preventing invasive fungal infections in patients receiving chemotherapy for acute myeloid leukemia (AML).
- Conditions
- Acute Myeloid Leukemia, Adult Acute Monoblastic Leukemia, Adult Acute Monocytic Leukemia, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT01307579
- Testing
- Caspofungin Acetate, Fluconazole, Laboratory Biomarker Analysis
- Where
- 179 sites in United States, Canada and 1 more
- Volunteers
- 517 people
- Sponsor
- Children's Oncology Group
Aspergillosis, Candidiasis
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
Fever and infection are serious complications of cancer treatment such as bone marrow transplant, especially when white blood cell counts are low.
- Conditions
- Aspergillosis, Candidiasis, Fungemia, Mycoses
- Trial name
- NCT00001937
- Testing
- FK463, Fluconazole
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- National Cancer Institute (NCI)
Histoplasmosis, Sporotrichosis
Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis
OBJECTIVES: I. Identify a preferred oral fluconazole dose regimen for patients with non-acute histoplasmosis or blastomycosis, or ulcerocutaneous or deep sporotrichosis. II.
- Conditions
- Histoplasmosis, Sporotrichosis, Blastomycosis
- Trial name
- NCT00004808
- Testing
- fluconazole
- Volunteers
- 78 people
- Sponsor
- National Center for Research Resources (NCRR)
Meningitis, HIV Infections
Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis
The study is intended to examine the efficacy of fluconazole for the treatment of coccidioidal meningitis in patients with new onset of infection, relapse of previous infection, or failed previous therapy.
- Trial name
- NCT00002010
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Sponsor
- Pfizer
Autism Spectrum Disorder
Study of Fluconazole in Children With Autism Spectrum Disorder
Antifungal therapy is widely used for individuals with Autism Spectrum Disorders (ASD). The current investigation will examine the effects of fluconazole on behavioral functioning among children with ASD.
- Trial name
- NCT00936182
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- The Center for Autism and Related Disorders
Nephrolithiasis, Nephrocalcinosis
Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D Levels
Hypercalciuria is one of the most frequent metabolic disorders associated with nephrolithiasis and/or nephrocalcinosis leading to Chronic Kidney Disease (CKD) and bone complications in adults.
- Conditions
- Nephrolithiasis, Nephrocalcinosis, Hypercalciuria
- Trial name
- FLUCOLITH (NCT04495608)
- Testing
- Fluconazole
- Where
- 11 sites in France
- Volunteers
- 56 people
- Sponsor
- Hospices Civils de Lyon
Cryptococcal Meningitis
Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis
This study will examine the effectiveness and safety of a combination treatment for cryptococcal meningitis, a fungal infection common in persons with acquired immune deficiency syndrome (AIDS) in the developing world.
- Trial name
- NCT00145249
- Testing
- Amphotericin B, Fluconazole
- Where
- 15 sites in United States, Thailand
- Volunteers
- 143 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Candidiasis, Oral, HIV Infections
Comparative Randomized Study of the Efficacy, Safety, and Toleration of Fluconazole Oral Suspension or Nystatin Oral Suspension in the Treatment of Patients With Oropharyngeal Candidiasis in Association With the Acquired Immunodeficiency Syndrome
To compare the efficacy, safety, and toleration of fluconazole as a single daily oral suspension for 14 days versus nystatin oral suspension 4 times daily for 14 days in the treatment of oropharyngeal candidiasis in patients with…
- Trial name
- NCT00002112
- Testing
- Nystatin, Fluconazole
- Where
- 5 sites in United States
- Sponsor
- Pfizer
Sporotrichosis
Phase II Study of Fluconazole for Lymphocutaneous and Visceral Sporotrichosis
OBJECTIVE: I. Evaluate the efficacy of fluconazole in patients with lymphocutaneous or visceral sporotrichosis.
- Trial name
- NCT00004938
- Testing
- fluconazole
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)