Clinical trials: Fluid Resuscitation
Burns
Albumin Use in Burn Patients
This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.
- Trial name
- NCT00609414
- Where
- 12 sites in United States, Canada
- Volunteers
- 460 people
- Sponsor
- University of North Carolina, Chapel Hill
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Shock, Critical Illness
Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation
The purpose of this study is to determine whether intravenous fluid management using lower chloride solutions (Hartmann's solutions and Plasmalyte®) will result in better outcome when compared to management using high chloride…
- Trial name
- CHLORIDE (NCT00885404)
- Testing
- Lower chloride fluids (Hartmann's solution and Plasmalyte®)
- Where
- Australia
- Volunteers
- 7,000 people
- Sponsor
- Austin Health
Cancer, Septic Shock
Evaluation of Fluid Resuscitation in Children With Cancer With Severe Sepsis / Septic Shock
Retrospective study to evaluate the characteristics of patients and of fluid resuscitation during intensive care unit hospitalization of patients under septic chock.
- Conditions
- Cancer, Septic Shock, Other Fluid Overload
- Trial name
- NCT01304680
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Grupo de Apoio ao Adolescente e a Crianca com Cancer
Shock, Septic
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study
The objective of this pilot study is to assess overall feasibility prior to embarking on a larger randomized pragmatic trial comparing the clinical effectiveness of fluid resuscitation with NS versus LR for pediatric patients…
- Trial name
- PRoMPT BOLUS (NCT03340805)
- Testing
- Lactated Ringer, Normal saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Philadelphia
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Fluid Resuscitation
Pediatric Fast Fluid Randomized Controlled Trial
The purpose of this study is to determine the impact of syringe size on the amount of time it takes a health care provider to administer a known volume (900 mL) of resuscitation fluid to a non-clinical, toddler-sized, model.
- Trial name
- NCT01494116
- Testing
- 900 mL of 0.9% Normal Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McMaster Children's Hospital
Septic Shock
Lung Ultrasound-guided Fluid Resuscitation in Neonatal Septic Shock
object name: Lung ultrasound-guided fluid resuscitation in neonatal septic shock. type of study: prospective observational study.
- Trial name
- LUGFRINSS (NCT06144463)
- Testing
- lung ultrasound-guided fluid resuscitation
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Guangdong Second Provincial General Hospital
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fluid Responsiveness, Echocardiography
Echocardiography Guided Fluid Resuscitation in Critically Ill Patients.
To compare between the impact of echocardiography guided fluid resuscitation and clinically guided fluid resuscitation on critically ill patients in hospital outcome.
- Trial name
- NCT03296319
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Sepsis, Systemic Inflammatory Response Syndrome
PPV to Guide Fluid Management in the PICU
Children who are critically ill often require large amounts of fluid during their acute illness. It has been shown in multiple studies that appropriate administration of fluid decreases morbidity and mortality, but giving too…
- Trial name
- PPV (NCT02308371)
- Testing
- Automated Pulse Pressure Variation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Cardiac Diseases
The Use of Colloid Versus Crystalloid in Post-operative Pediatric Cardiac Patients for Fluid Resuscitation
The purpose of the study is to help determine if either crystalloid solution or colloid solution is more advantageous as a resuscitative fluid in post-operative pediatric cardiac patients.
- Trial name
- NCT00464126
- Testing
- 5% albumin, crystalloid
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Vanderbilt University Medical Center
Shock
Fluid Resuscitation In Trauma: What Are The Best Strategies And Fluids?
Illustration of the differential effects of commonly used resuscitation fluids, including isotonic crystalloids, natural and artificial colloids, hypertonic and hyperoncotic solutions to prevent the cellular injury through wiser…
- Trial name
- NCT05738265
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Fluid Therapy, Vasopressor Therapy
Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients
The goal of this woldwide observational study is to investigate various aspects of fluid and vasopressor therapy in critically ill invasively ventilated patients.
- Conditions
- Fluid Therapy, Vasopressor Therapy, Critical Illness, Invasive Ventilation
- Trial name
- PRoFLUID (NCT05968066)
- Where
- Netherlands
- Volunteers
- 2,508 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Brain Injuries
Feasibility Trial of Traumatic Brain Injured Patients Randomized in the Prehospital Setting to Either Hypertonic Saline and Dextran Versus Normal Saline
This clinical trial will evaluate the ease of conducting a randomized trial on patients with severe head injury who are cared for by paramedics in the out of hospital setting.
- Trial name
- TOPHR HIT (NCT00878631)
- Testing
- hypertonic saline mixed with dextran, Normal Saline
- Where
- 2 sites in Canada
- Volunteers
- 113 people
- Sponsor
- Unity Health Toronto
Septic Shock, Pediatric Critical Illness
Randomized Control Study in REsuscitation of SEpsis Trial
Crystalloids vs. Synthetic Plasma for Fluid Resuscitation in Children with Sepsis - REsuscitation of SEpsis Trial (RESET): A Comparative and Feasibility Study This research study, called the REsuscitation of SEpsis Trial (RESET)…
- Trial name
- RESET (NCT07035509)
- Testing
- Pharmaceutical fresh frozen plasma, Normal Saline, Ringer lactate (RL)
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Dengue Shock Syndrome
Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS)
Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are among the leading causes of pediatric hospitalization in Asia.Mortality rates range from 1% at centres experienced in fluid resuscitation, to upto 44% in…
- Trial name
- NCT00966628
- Testing
- Hypertonic sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Diabetes
Fluid Resuscitation for Pediatric Diabetic Ketoacidosis
Randomized trial to determine if the volume of fluid administration in pediatric patients with DKA impacts the rate of normalization of serum bicarbonate, pH as well as the length of treatment
- Trial name
- NCT01701557
- Testing
- slow fluid rate, fast fluid rate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Fluid Therapy
Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients
The aim of the FLUID Trial is to conduct a pragmatic, multi-centre, open label randomized cluster cross-over trial (RCT) to determine whether fluid administration with 0.9% saline as compared to Ringer's lactate decreases death…
- Trial name
- FLUID (NCT04512950)
- Testing
- Ringer's lactate, 0.9% saline
- Where
- 7 sites in Canada
- Volunteers
- 43,626 people
- Sponsor
- Ottawa Hospital Research Institute