Clinical trials: Fluid Therapy
Resuscitation, Shock
Pediatric Fast Fluid Trial 2
The purpose of this study is to determine which of two commonly used methods of manual pediatric fluid resuscitation (The "Push-Pull Technique" vs.
- Conditions
- Resuscitation, Shock, Fluid Therapy, Pediatrics
- Trial name
- PFFT2 (NCT01774214)
- Testing
- Push-Pull technique, Disconnect-Reconnect Technique
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster Children's Hospital
Arthritis
Synovial Fluid Bank From Arthritic Patients
The objectives of this group project is to collect synovial fluid (SF) and paired sera and carry out preclinical studies to evaluate, alone or by combination testings, the potential of novel biomarkers for their prevalence and…
- Trial name
- NCT00512343
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Gilles Boire
Leptomeningeal Metastasis, Leptomeningeal Disease
A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide
The FORESEE Study is a multi-center, prospective clinical trial enrolling patients with Breast or Non-Small Cell Lung Cancer (NSCLC) who have suspicious or confirmed Leptomeningeal Metastases (LM).
- Conditions
- Leptomeningeal Metastasis, Leptomeningeal Disease, Leptomeningeal Neoplasms, Breast Cancer
- Trial name
- FORESEE (NCT05414123)
- Testing
- CNSide
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Biocept, Inc.
Shock Hypovolemic, Shock, Septic
Management of Shock in Children With SAM or Severe Underweight and Diarrhea
Diarrhea is one of the leading causes of under-five childhood mortality and accounts for 8% of 5.4 million global under-5 deaths.
- Conditions
- Shock Hypovolemic, Shock, Septic, Blood Transfusion, Adrenaline
- Trial name
- NCT04750070
- Testing
- Blood and Dopamine, Blood and adrenaline
- Where
- Bangladesh
- Volunteers
- 135 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cerebral Edema, Diabetic Ketoacidosis
Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis
The investigators will conduct a randomized controlled trial comparing four different intravenous (IV) fluid treatment protocols for pediatric diabetic ketoacidosis (DKA).
- Trial name
- NCT01365793
- Testing
- 0.45% saline replacement fluid, 0.9% saline replacement fluid, 0.45% saline intravenous fluid
- Where
- 13 sites in United States
- Volunteers
- 1,389 people
- Sponsor
- University of California, Davis
Circulatory Failure, Shock State
Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children
In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children.
- Conditions
- Circulatory Failure, Shock State, Fluid Therapy
- Trial name
- FAST (NCT07522580)
- Testing
- validation a test of fluid-responsiveness in critically ill children
- Where
- 4 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Bordeaux
Osteoarthritis, Knee
Is Phonophoresis Treatment Effective?
The specimens from patients as knee osteoarthritis diagnosed who was applied ibuprofen phonophoresis will be analyzed.
- Trial name
- NCT02358707
- Testing
- Ibuprofen phonophoresis
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Cukurova University
Tooth, Impacted, Tooth Diseases
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2…
- Conditions
- Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT05484401
- Testing
- Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
HIV Infections
Safety and Pharmacokinetic Study of Fixed Dose Combination of Zidovudine, Lamivudine, and Nevirapine in HIV-Infected Children in Thailand
In 2005, there were 50,620 HIV-infected children living in Thailand. Current anti-HIV regimens, comprised of individual pills for each drug, frequently lead to missed doses.
- Trial name
- NCT00672412
- Testing
- GPO-Vir Z30 tablet, Lamivudine, Nevirapine
- Where
- 4 sites in Thailand
- Volunteers
- 42 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acne Vulgaris
Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris
The aim of this study is to evaluate a complete acne regimen consisting of a medication (Benzaknen® 5% Gel), and 2 cosmetic products Dermotivin® Soft Liquid soap and Cetaphil® Dermacontrol Moisturizer SPF30 in patients with acne.
- Trial name
- Benzac (NCT02589405)
- Testing
- Benzoyl Peroxide, Dermotivin® Soft Liquid cleanser, Cetaphil® Dermacontrol Moisturizer SPF30
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Cognitive Disorders, HIV Infections
HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs
The purpose of this study is to see whether anti-HIV drugs that reduce HIV in the blood also reduce HIV in the cerebrospinal fluid (CSF). CSF is the fluid found around the brain and spinal cord.
- Trial name
- NCT00001103
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pancreas Adenocarcinoma
Verification of Predictive Biomarkers for Pancreatic Cancer Treatment Using Multicenter Liquid Biopsy
This study is for verification of predictive biomarkers for pancreatic cancer treatment using multi-center liquid biopsy.
- Trial name
- NCT04241367
- Where
- South Korea
- Volunteers
- 420 people
- Sponsor
- National Cancer Center, Korea
Lung Cancer
Cerebrospinal Fluid Levels of Erlotinib in Patients Receiving Erlotinib For Stage III Non-Small Cell Lung Cancer
RATIONALE: Determining whether erlotinib passes into the cerebrospinal fluid may help in planning treatment for some types of cancer.
- Trial name
- NCT00305617
- Testing
- antitumor drug screening assay
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cleveland Clinic
Postoperative Vomiting
Effect of Intravenous Fluid Therapy on Postoperative Vomiting in Children Undergoing Otorhinolaryngological Surgery
The purpose of this randomized clinical trial is to evaluate the interaction of intravenous fluid therapy during otorhinolaryngological surgery, on postoperative vomiting.
- Trial name
- NCT01575600
- Testing
- Intraoperative lactated Ringer's solution
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Ignacio Cortínez F.
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Neuroblastoma
Oral Liquid 13-cis-retinoic Acid (13-CRA)
An open label, randomised, multiple dose, cross-over relative bioavailability and pharmacokinetics trial of a novel oral liquid and capsule formulations of 13-CRA administered to patients from 0 months - < 21 years.
- Trial name
- My-CRA (NCT03291080)
- Testing
- Liquid 13-Cis Retinoic Acid, Extracted capsules 13-CRA
- Where
- 10 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nova Laboratories Limited
Colectomy, Pancreatectomy
Implementation of a GDT Algorithm for Major Surgery Patients
This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.
- Conditions
- Colectomy, Pancreatectomy, Fluid Therapy
- Trial name
- NCT02509910
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Philipps University Marburg
Plan Warts
Comparison of Topical 5%Potassium Hydroxide vs Liquid Nitrogen in the Treatment of Plane Warts
ABSTRACT Objective: To study the efficacy while comparing Potassium hydroxide 5% with liquid nitrogen in treatment of plane warts. Study design: Randomized-controlled trial (RCT), (Double-blind).
- Trial name
- NCT05895071
- Testing
- 5%potassium hydroxide, Liquid nitrogen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Epidermolysis Bullosa (EB), Chronic Wounds
Topical Insulin Versus Irradiated Amniotic Fluid Gel for Wound Healing in Epidermolysis Bullosa
This study aims to evaluate and compare the safety and efficacy of topical insulin and topical irradiated amniotic fluid gel in promoting wound healing in patients with epidermolysis bullosa (EB).
- Conditions
- Epidermolysis Bullosa (EB), Chronic Wounds, Wound Healing
- Trial name
- EB-INS-AFG (NCT07907523)
- Testing
- Topical Insulin (Actrapid®), Topical Irradiated Amniotic Fluid Gel, No active study treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University