Clinical trials: Food Allergy Peanut
Peanut Allergy
Safety of Epicutaneous Immunotherapy for the Treatment of Peanut Allergy
The purpose of this phase 1b study is to evaluate the safety and tolerability of repeated epicutaneous applications of peanut proteins using a patch delivery system (Viaskin device) in peanut allergic subjects.
- Trial name
- NCT01170286
- Testing
- Whole peanut extract
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- DBV Technologies
Peanut Hypersensitivity
Boiled Peanut Oral Immunotherapy
Prospective Phase 1 clinical trial providing proof of concept data on boiled peanut oral immunotherapy (OIT) for the treatment of peanut allergy in children.
- Trial name
- BPOIT (NCT04090203)
- Testing
- Boiled Peanut Powder
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Alton Melton
Food Allergy Peanut
Novel Treatment for Patients With Peanut Allergy: Intralymphatic Immunotherapy
Use of three intralymphatic injections of peanut allergen one month apart to induce tolerance to peanut in peanut allergic people.
- Trial name
- NCT04200989
- Testing
- Peanut allergen
- Where
- United States
- Sponsor
- Scripps Health
Allergy to Egg, Allergy to Peanut
Basophil Activation Test (BAT) Sensitivity in Child Food Allergy
Child food allergy represent 6 to 8% of child in industrialised country. Within this allergy, peanuts and egg allergy are one of the most common.
- Trial name
- TAB-TPO (NCT01966640)
- Testing
- Basophil Activation Test
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Rouen
Food Allergy, Food Allergy in Children
Understanding the Immune System's Role in Tree Nut and Peanut Allergies: Key Biomarkers for Diagnosis and Treatment Monitoring and Treatment Targets
Peanut and tree nuts belong to the main elicitors of pediatric food allergy and are the main cause of near fatal reactions in children requiring emergency management.
- Conditions
- Food Allergy, Food Allergy in Children, Food Allergy Peanut, Tree Nut Allergies
- Trial name
- Markers4Care (NCT06554691)
- Where
- 2 sites in Luxembourg
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Peanut Allergy
Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy
This clinical research study investigates the safety, tolerability and efficacy of a peanut SLIT-tablet in adults, adolescents, and children with peanut allergy.
- Trial name
- NCT05440643
- Testing
- Peanut SLIT-tablet
- Where
- 42 sites in United States, Canada
- Volunteers
- 209 people
- Sponsor
- ALK-Abelló A/S
Peanut Allergy
Oral Immunotherapy for Peanut Allergic Patients
Multicenter, double-blind, randomized, placebo-controlled phase I/II study to determine the safety, tolerability, potential efficacy and dose finding of INP20, an oral immunotherapy in peanut-allergic patients.
- Trial name
- NCT04163562
- Testing
- INP20
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- InnoUp Farma S.L.
Allergy
A Safety and Efficacy Study of Xolair in Peanut Allergy
This is a 38-week, randomized, double-blind, placebo-controlled, parallel group trial of approximately 150 patients who have a history of immediate hypersensitivity reaction to peanut protein.
- Trial name
- NCT00086606
- Testing
- Xolair (omalizumab)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Genentech, Inc.
Allergy, Peanut, Peanut Allergy
Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients
This is a phase II trial that aims at evaluating the safety and tolerability of oral encapsulated fecal microbial transplantation therapy (MTT) in peanut allergic patients.
- Conditions
- Allergy, Peanut, Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis
- Trial name
- NCT05695261
- Testing
- Microbial Transplantation Therapy, Antibiotic, Oral Immunotherapy (OIT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Rima Rachid
Peanut Allergy
ARTEMIS Peanut Allergy In Children
The purpose of this study is to demonstrate the efficacy and safety of AR101 through oral immunotherapy (OIT) in peanut-allergic children.
- Trial name
- ARTEMIS (NCT03201003)
- Testing
- AR101 powder provided in capsules & sachets
- Where
- 18 sites in France, Germany and 5 more
- Volunteers
- 175 people
- Sponsor
- Aimmune Therapeutics, Inc.
IgE-Mediated Cow Milk Allergy, Peanut Allergy
Using Commonly Available Food Products To Treat Food Allergy
Food allergy affects 1 in 30 children, and is the commonest trigger for life-threatening reactions (anaphylaxis) in this age group.
- Trial name
- NATASHA (NCT05503446)
- Testing
- Peanut in common foods or supermarket-sourced cow's milk (CM)
- Where
- 5 sites in United Kingdom
- Volunteers
- 216 people
- Sponsor
- University of Southampton
Food Allergies, Peanut Allergies
A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment)
The goal of this observational study is to learn about the long-term outcomes of children and young people who underwent an 18-month course of oral immunotherapy (OIT) treatment for peanut, egg or milk allergy.
- Conditions
- Food Allergies, Peanut Allergies, Egg Allergy, Milk Allergy
- Trial name
- LPEM (NCT07359183)
- Where
- Australia
- Volunteers
- 147 people
- Sponsor
- Murdoch Childrens Research Institute
Oral Immunotherapy for Food Allergy, Tree Nut Allergy
The NACHO Trial (Nut Allergy Children OIT)
Most food allergies that begin in early childhood are mild and resolve by school age, but nut allergies persist in about 80-90% of individuals into adulthood.
- Conditions
- Oral Immunotherapy for Food Allergy, Tree Nut Allergy, Cashew Nut Allergy
- Trial name
- NCT06930950
- Testing
- Cashew nut oral immunotherapy
- Where
- Finland
- Volunteers
- 45 people
- Sponsor
- HUS Skin and Allergy Hospital
Peanut Hypersensitivity, Food Allergy
FARE Peanut SLIT and Early Tolerance Induction
Primary Objective: To determine if 36 months of peanut SLIT as an early intervention in subjects ages 1 to 4 years induces clinical desensitization.
- Conditions
- Peanut Hypersensitivity, Food Allergy, Food Hypersensitivity, Peanut Allergy
- Trial name
- FARE/SLIT (NCT02304991)
- Testing
- Liquid Peanut Extract
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Peanut Allergy
Allergy Experience Study
People who are undergoing oral immunotherapy for food allergy treatment can feel anxious about the treatment process, particularly when they have allergic responses (e.g., hives, vomiting, nausea) during the dosing process.
- Trial name
- NCT03513965
- Testing
- Symptoms as Positive Signals Mindset, Symptoms as Side Effects Mindset
- Volunteers
- 50 people
- Sponsor
- Stanford University
Hypersensitivity, Food Allergy
Clinical Study Using Biologics to Improve Multi OIT Outcomes (COMBINE)
Food allergy is a serious public health concern that causes potentially-life threatening reactions in affected patients. The prevalence of food allergy in the United States (U.S.) has increased substantially and now affects 15…
- Conditions
- Hypersensitivity, Food Allergy, Hypersensitivity, Food, Peanut Hypersensitivity
- Trial name
- NCT03679676
- Testing
- Omalizumab, Dupilumab
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- Stanford University
Allergy, Peanut Allergy
Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)
The primary objective of this study is to assess the 6-month safety of DBV712 250 micrograms (mcg) in subjects 1 through 3 years of age with peanut allergy.
- Trial name
- NCT07003919
- Testing
- DBV712 250 mcg
- Where
- 91 sites in United States, Australia and 6 more
- Volunteers
- 480 people
- Sponsor
- DBV Technologies
Allergy;Food
Relevance of Sensitization to Legumes in Children Allergic to Peanut
The objectives of this study are to determine in children allergic to peanut (i) the prevalence of sensitization to other legumes, (ii) the prevalence of allergy to each legume in patients who are sensitized to it (iii ) the…
- Trial name
- NCT04329078
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Peanut Allergic Subjects, Peanut Allergies
Oral Immunotherapy for Children With Peanut Allergy
This clinical trial aims to investigate if oral immunotherapy can help children with peanut allergy tolerate peanut. Children aged 6 months to 4 years can take part in the trial.
- Conditions
- Peanut Allergic Subjects, Peanut Allergies, Peanut Hypersensitivity, Food Allergy Peanut
- Trial name
- NCT07895095
- Testing
- Oral immunotherapy with peanut
- Where
- 5 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- Laura Ozer Kettner
Peanut Allergy
Epicutaneous Immunotherapy in Peanut Allergy in Children
This study aims at showing that Epicutaneous Immunotherapy with peanut proteins is safe and efficacious for desensitizing children with peanut allergy.
- Trial name
- ARACHILD (NCT01197053)
- Testing
- Epicutaneous Immunotherapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris