Clinical trials: Food Safety
Egg Hypersensitivity
Safety of Nasal Influenza Immunisation in Egg Allergic Children
Egg allergy is common in early childhood, affecting at least one in 50 preschool children. Influenza ("'flu") vaccines contain egg protein, as the vaccine is cultured in hen's eggs.
- Trial name
- SNIFFLE (NCT01859039)
- Testing
- Administration of Live attenuated influenza vaccine
- Where
- 12 sites in United Kingdom
- Volunteers
- 282 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Peanut Allergy
CNP-201 in Subjects With Peanut Allergy
This study is a Phase 1b/2a clinical trial to assess the safety, tolerability, and pharmacodynamics of multiple ascending doses (Escalation Phase) of CNP-201 with the goal of identifying a safe and tolerable dose level to be…
- Trial name
- NCT05250856
- Testing
- CNP-201
- Where
- 17 sites in United States
- Volunteers
- 15 people
- Sponsor
- COUR Pharmaceutical Development Company, Inc.
Food Allergy
Improving the Safety of Oral Immunotherapy for Cow's Milk Allergy
Allergy to cow's milk is the most common food allergy affecting children. There is currently no accepted routine clinical therapy to cure milk allergy.
- Trial name
- SOCMA (NCT02216175)
- Testing
- SLIT to cow's milk, Low dose OIT, Conventional OIT to cow's milk
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 68 people
- Sponsor
- Imperial College London
Egg Allergy, Eligible for Vaccination Against Influenza
FluMist in Egg Allergic Patients
With the growing public health concerns of seasonal influenza and H1N1 in the United States, the primary means by which this can be addressed is with prevention, namely, vaccination against the influenza virus.
- Trial name
- FluEMIST (NCT01248208)
- Testing
- FluMist intranasal influenza vaccine, Intramuscular influenza injection ("flu shot")
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Walter Reed Army Medical Center
Food Allergy
Safety of Oral Food Challenge With Cow's Milk Proteins in Children With Food Allergy
The aim of the study is to assess the safety of an oral food challenge (OFC) with cow's milk proteins and to assess the tolerance of cow's milk proteins in children with a food allergy after introducing cow's milk into the diet.
- Trial name
- NCT04312438
- Testing
- oral food challenge with cow's milk proteins
- Where
- Poland
- Volunteers
- 1 people
- Sponsor
- Wroclaw Medical University
Food Safety, Child Nutrition
MoreMilk Project: Milk Safety and Child Nutrition Impacts of a Training Scheme for Dairy Vendors in Eldoret, Kenya
The objective of the MoreMilk trial is to assess the effect of a Training, Certification and Marketing intervention for milk vendors in the informal sector on the safety of the milk sold in the markets and on the nutrition of…
- Trial name
- NCT05117892
- Testing
- Training, certification and marketing scheme
- Where
- Kenya
- Volunteers
- 1,297 people, healthy volunteers welcome
- Sponsor
- The International Livestock Research Institute (ILRI)
Moderate Acute Malnutrition
Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-MAM (NCT06056089)
- Testing
- ready-to-use supplementary food (RUSF), ready-to-use therapeutic food (RUTF)
- Where
- 3 sites in Ethiopia
- Volunteers
- 2,400 people
- Sponsor
- Action Against Hunger USA
Peanut Allergy
HAL-MPE1 Safety and Tolerability Study
The aim of this study is to confirm safety and tolerability of incremental doses of HAL-MPE1 subcutaneous immunotherapy (SCIT) in peanut allergic adults, and subsequently assess the safety and tolerability in adolescents and…
- Trial name
- NCT02991885
- Testing
- HAL-MPE1
- Where
- 7 sites in United States, Canada
- Volunteers
- 42 people
- Sponsor
- HAL Allergy
Peanut Allergy
Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-201 in Subjects Ages 16-35 With Peanut Allergy
This study is a two-part Phase 1b/2a First-in-Human (FIH) randomized, double-blind, placebo-controlled clinical trial to assess the safety, tolerability, pharmacodynamics, and efficacy of multiple ascending doses of CNP-201 in…
- Trial name
- NCT04950504
- Testing
- CNP-201
- Where
- 9 sites in United States
- Volunteers
- 9 people
- Sponsor
- COUR Pharmaceutical Development Company, Inc.
Urea Cycle Disorder, Inborn Errors of Metabolism
A Collection of Case Studies in Infants With UCD to Evaluate Infant Growth and the Safety of a New Medical Food for UCD
Original study: Study aims to enroll 3-5 children with confirmed Urinary Cycle Disorder (UCD). Subjects meeting the inclusion and exclusion criteria are included during the baseline visit.
- Trial name
- NCT03911089
- Testing
- UCD Anamix Infant
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nutricia Research
Food Allergy
Long-term Extension Study of Ligelizumab in Food Allergy
This was an extension study to evaluate the long-term safety and efficacy of ligelizumab in participants who completed a ligelizumab Phase III study in food allergy.
- Trial name
- NCT05678959
- Testing
- Ligelizumab 120 mg, Ligelizumab 240 mg
- Where
- 49 sites in United States, Australia and 7 more
- Volunteers
- 163 people
- Sponsor
- Novartis Pharmaceuticals
Food Allergy in Children, Cow Milk Allergy
Nutrition Sufficiency, Allergy Efficacy and Safety of Neocate Jr in Children With Food Protein Allergy
The main purpose of this study is to evaluate efficacy and safety of an amino acid-based formula Neocate Jr in children with food protein allergy, and to evaluate nutrition sufficiency of Neocate Jr in 1 to 10 years old children…
- Trial name
- NCT05406141
- Testing
- Amino acid formula (Neocate Jr)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
NAFLD
Study of the Safety and Tolerability of AXA1957 in Adolescent Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)
This is a randomized, single blind study to determine whether AXA1957, a novel composition of amino acids, is safe and well tolerated.
- Trial name
- NCT04073407
- Testing
- AXA1957
- Where
- 4 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- Axcella Health, Inc
Prader-Willi Syndrome, Hyperphagia
Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome
This Phase 2b/3 double-blind, placebo-controlled study will evaluate the safety, tolerability, and effects of livoletide on food-related behaviors in patients with Prader-Willi Syndrome (PWS).
- Trial name
- ZEPHYR (NCT03790865)
- Testing
- Livoletide
- Where
- 37 sites in United States, Australia and 6 more
- Volunteers
- 158 people
- Sponsor
- Millendo Therapeutics SAS
Peanut Allergy
Safety of MOON101 for the Treatment of Peanut Allergy
The goal of this open-label, single escalating dose study in 3 sequential groups: adults, adolescents, and children with peanut allergy is to assess the safety of MOON101. The main question it aims to answer is: 1.
- Trial name
- SURVEYOR (NCT07580898)
- Testing
- Dose A, Dose B, Dose C
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Moonlight Therapeutics, Inc.
Allergy, Peanut
Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age
The primary purpose of this study is to assess the efficacy and safety of daily DBV712 250 micrograms (mcg) to induce desensitization to peanut in peanut-allergic children 4-7 years of age over a 12-month double-blind…
- Trial name
- VITESSE (NCT05741476)
- Testing
- DBV712
- Where
- 87 sites in United States, Australia and 7 more
- Volunteers
- 600 people
- Sponsor
- DBV Technologies
Ulcerative Colitis, Inflammatory Bowel Diseases
Open Label Study to Assess Safety & Efficacy of QD for Induction of Remission in Pediatric Patients with UC
To date, there are no reports on the use of QD in pediatric patients with UC. There is a great need to increase the repertoire of anti-inflammatory interventions for remission induction, especially in children given the notorious…
- Trial name
- NCT06777706
- Testing
- QD (Qing Dai)
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Shaare Zedek Medical Center