Clinical trials: Food Systems
Food Allergy in Children, Milk Allergy
Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study
This study investigates the efficacy and safety of two different OIT schemes to treat milk and egg allergic children
- Conditions
- Food Allergy in Children, Milk Allergy, Egg Allergy
- Trial name
- compITO (NCT06976775)
- Testing
- "Rush" regimen, "Conventional" regimen
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Pablo Rodríguez del Rio
Peanut Hypersensitivity, Anaphylaxis
PEAnut Anaphylaxis Predictors
Peanut allergy can be life-threatening. Current diagnostic techniques for peanut allergy have high sensitivity, but not high specificity.
- Trial name
- PEAAP (NCT02424136)
- Testing
- Questionnaire, Peanut Skin prick test, Fraction of exhaled nitric oxide
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- John Hunter Children's Hospital
Food Allergy in Infants
Early Allergen System Experience
Multiple clinical trials have demonstrated that early allergen introduction, feeding babies common food allergens before six months, decreases children's risk of developing a food allergy.
- Trial name
- EASE (NCT06262867)
- Testing
- Ready. Set. Food! Stage 1 Mix ins
- Where
- United States
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Prollergy dba Ready Set Food
Peanut Allergy
VE416 for Treatment of Food Allergy
This is a single-center, randomized, double-blind trial with four arms evaluating VE416 as pretreatment or concurrent treatment in comparison to low-dose peanut oral immunotherapy (PNOIT) alone.
- Trial name
- NCT03936998
- Testing
- Vancomycin plus VE416 before PNOIT, Vancomycin plus VE416 with PNOIT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Rhinitis, Allergic, Asthma, Allergic
Food-specific IgG4-guided Elimination Diets Improve Allergy Symptoms in Children
Allergic diseases in children are major public health concerns due to their widespread and rising prevalence. The most classic pathway to trigger allergy is type I allergy mediated by immunoglobulin E(IgE), but the role of…
- Conditions
- Rhinitis, Allergic, Asthma, Allergic, Conjunctivitis, Allergic, Atopic Dermatitis
- Trial name
- NCT06063044
- Where
- China
- Volunteers
- 407 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peanut Allergy
Safety of MOON101 for the Treatment of Peanut Allergy
The goal of this open-label, single escalating dose study in 3 sequential groups: adults, adolescents, and children with peanut allergy is to assess the safety of MOON101. The main question it aims to answer is: 1.
- Trial name
- SURVEYOR (NCT07580898)
- Testing
- Dose A, Dose B, Dose C
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Moonlight Therapeutics, Inc.
Food Allergy
Baked Egg or Egg Oral Immunotherapy for Children With Egg Allergy
The purpose of this study is to compare Baked Egg vs. Egg Oral Immunotherapy for inducing sustained unresponsiveness to egg exposure in children.
- Trial name
- CoFAR7 (NCT01846208)
- Testing
- Egg Oral Immunotherapy, Baked Egg
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Hugh A Sampson, MD
Peanut Allergy
Salvage Peanut Oral Immunotherapy Study
The purpose of this trial is to study the safety of rescue peanut oral immunotherapy followed by the introduction of dietary peanut for patients with peanut allergy who have lost desensitization during a peanut immunotherapy…
- Trial name
- SOIT (NCT03251508)
- Testing
- Peanut OIT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of North Carolina, Chapel Hill
Atopic Dermatitis, Food Allergy
Skin Barrier Abnormalities and Oxidative Stress Response
This is a prospective, single-site controlled observational study designed to comprehensively determine whether children and adults with atopic dermatitis (AD) and food allergy (FA) have skin abnormalities which distinguish them…
- Trial name
- NCT04606615
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Diabetes
Food Intake and Appetite in the Children of Mothers With Diabetes
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism. Insulin secretion will be measured during infusions of escalating doses of atropine.
- Trial name
- NCT00339313
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Nut Hypersensitivity, Child
Phenotypical Characterization of Peanut Allergic Children
Peanut allergy (PA) has been well studied and its prevalence was estimated up to 1.3% in Europe. Tree nut (TN) allergy and PA are clinically similar and often coexist, TN allergy prevalence ranged from 0.05 to 4.9 %.
- Conditions
- Nut Hypersensitivity, Child, Legumes Allergy, Tree Nut Allergy
- Trial name
- NCT02961452
- Testing
- Cross reaction detection
- Volunteers
- 317 people
- Sponsor
- Lille Catholic University
Food Allergy
Registry of Food Allergy Oral Immunotherapy Treatment
The purpose of this patient registry is to demonstrate safety and efficacy of food oral immunotherapy in food allergic patients. Factors that lead to adverse reactions will be identified.
- Trial name
- NCT03059589
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Food Allergy Support Team
Atopy, Asthma
Vitamin A Supplementation at Birth and Atopy in Childhood
INTRODUCTION Eight trials studying the effect of providing neonatal vitamin A supplementation (NVAS) have been reported, and another four are underway to test whether NVAS should become WHO policy.
- Conditions
- Atopy, Asthma, Eczema, Food Allergy
- Trial name
- NCT01779180
- Where
- Guinea-Bissau
- Volunteers
- 2,000 people
- Sponsor
- Bandim Health Project
Food Allergy Suspected, Food Allergy Proved
Association Between Asthma and Food Allergy
Prevalences of food allergies and asthma increased in the population during the last decades. These two pathologies, responsible for a real burden, are often associated and are to be considered as comorbidities; this aspect is…
- Trial name
- AAAli (NCT02884583)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Milk Allergy, Cow's, Food Allergy in Children
Oral Immunotherapy for Children With Cow's Milk Allergy
This clinical trial aims to investigate if oral immunotherapy can help children with cow's milk allergy tolerate cow's milk. Children aged 6-18 months can take part in the trial.
- Conditions
- Milk Allergy, Cow's, Food Allergy in Children, Food Allergies
- Trial name
- NCT07768696
- Testing
- Oral immunotherapy with cow's milk
- Where
- 5 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- Laura Ozer Kettner
Food Allergy, Food Allergy in Infants
Basophil Activation Test to Diagnose Food Allergy
The BAT II Study is a cross-sectional diagnostic study in which children with suspected IgE-mediated allergy to foods (namely cow's milk, egg, sesame and cashew), as defined by a history of an immediate-type allergic reaction to…
- Conditions
- Food Allergy, Food Allergy in Infants, Food Allergy in Children, Food Allergen Sensitisation
- Trial name
- BAT2 (NCT03309488)
- Testing
- Oral food challenge
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Peanut Allergy, Nut Allergy
Immune-supportive Diet and Gut Permeability in Allergic Children
Peanut and nut allergy can be life threatening. Some patients have very low threshold levels (i.e. the amounts of peanut and nuts to which the patients react), others react to higher doses.
- Trial name
- DIAMETER (NCT05667610)
- Testing
- Immune-supportive diet, Standard care
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Cow's Milk Protein Allergy
The Journey of Children With Cow's Milk Protein Allergy in Mexico.
To gain insights on the application, use and effectiveness of Frisolac Gold Intensive HA and Frisolac Gold PEP AC with reference to improvement of CMPA symptoms and to determine the methodology used by Mexican Health Care…
- Trial name
- Friso02 (NCT04596059)
- Testing
- Frisolac Gold Intensive HA
- Where
- 4 sites in Mexico
- Volunteers
- 79 people
- Sponsor
- FrieslandCampina
Can Milk Allergic Patients Tolerate Baked Milk Products
Oral Immunotherapy With Baked Milk Products for Patients Allergic to Cow's Milk - A Multicenter Study
Based on the current knowledge, the investigators hypothesized that most children with milk allergy in Israel would be able to ingest baked milk products daily, thus benefiting from improved nutrition and dietary variety and…
- Trial name
- NCT01760837
- Testing
- Baked milk products to cow's milk allergic patients
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Wolfson Medical Center
- Egg Hypersensitivity
Time-limited Specific Oral Tolerance Induction in Children With Severe Egg Allergy
To evaluate the efficacy of a 6-month specific oral tolerance induction (SOTI) protocol in inducing tolerance (maximal dose of raw egg emulsion tolerated) in children with severe IgE-mediated egg allergy and a history of at least…
- Trial name
- EGGSOTI (NCT01379651)
- Testing
- Specific oral tolerance induction
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli