Clinical trials: Fractures, Bone
Osteoporosis, Postmenopausal, Osteoporosis Fracture
New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis Fracture, Osteoporosis, Severe
- Trial name
- NCT06525688
- Testing
- Bone, Serum and Plasma sample
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Fractures
Evaluation of the Change in Length of the Leg in Children After Treatment of Femur Fractures.
Femur fractures are a common injury in the Pediatric population. Despite their high incidence little do we know about the long term implications on the bones' length.
- Trial name
- NCT00355420
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Supracondylar Humerus Fracture
Supracondylar Post-Operative Pain Study
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning.
- Trial name
- NCT03759028
- Testing
- Ibuprofen, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Femur Distal Fracture, Nonunion of Fracture
Distal Femur Fracture Nonunion - Statistical Analysis Plan
Here the investigators describe the statistical analysis plan for the study assessing the prediction of fracture nonunion leading to secondary surgery in patients with distal femur fractures.
- Trial name
- NCT05163795
- Testing
- Lateral locking plate
- Where
- Finland
- Volunteers
- 299 people
- Sponsor
- Töölö Hospital
Bone Fractures
Splinting Versus Casting for Type I Supracondylar Fractures
Elbow fractures are very common in young children. Type I supracondylar fractures are stable fractures to the elbow that are treated conservatively across the world and typically heal very well without complications.
- Trial name
- NCT01912365
- Testing
- Above Elbow Cast, Long Arm Splint
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of British Columbia
Traumatology, Wounds and Injury
Sufentanil Versus Ketamine Intranasally in the Management of Severe Acute Trauma-related Pain in Children.
Pain is one of the most common reasons for children to attend emergency departments, particularly following traumatic injuries such as fractures, sprains, or contusions.
- Conditions
- Traumatology, Wounds and Injury, Fractures Bone, Analgesia
- Trial name
- SUF-KET-PED (NCT06968546)
- Testing
- Intranasal Sufentanil, Intranasal Ketamine (IN)
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Lenval
Femoral Neck Fracture
The Effect of Periarticular Multi-Drug Regimen on Pain After Partial Hip Replacement
This prospective randomized study aims to evaluate the effectiveness of periarticular multi-drug regimen injection on the relief of pain in patients undergoing partial hip replacement.
- Trial name
- NCT01112436
- Testing
- periarticular injection of multidrug regimen, none of medication preoperatively and intraoperatively
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Chung-Ang University Hospital
Femur Fracture
Pediatric Locking Nail for the Treatment of Femoral Fractures in Children
The purpose of this multi-center prospective clinical outcomes study is to determine validity and safety of the pediatric locking nail for femoral fracture management in children with open physes.
- Trial name
- PLN (NCT00725894)
- Testing
- Pediatric Locking Nail
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Zimmer Biomet
Supracondylar Humerus Fracture
Treatment of Pediatric Supracondylar Humeral Fractures With Novel Kirschner Wire Fixation Devices
A novel K-wire external fixation device was developed by the investigators. The K-wires can be connected by the device. After connection, the structure of the K-wires is transformed to an external skeletal fixator.
- Trial name
- NCT04122781
- Testing
- Novel K-wire fixation devices
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Distal Radius Fracture, Radiological Outcome
Cortical Comminution and Intra-articular Involvement in Distal Radius Fractures Can Predict Radiological Outcome. A Prospective Multicenter Study
Background: Although fractures of the distal radius are the most common skeletal injury, the utility of the available classification systems to predict fracture stability is limited.
- Trial name
- NCT01778673
- Testing
- Cast immobilization
- Where
- Sweden
- Sponsor
- Sundsvall Hospital
Simulation Based Medical Education
Optimizing Simulation-Based Training in Orthopedics: Exploring Deliberate Flawed Performance for Dynamic Hip Screw Osteosynthesis
Proximal femoral fractures (PFF) are associated with increased mortality when surgical intervention is delayed, with evidence supporting osteosynthesis within 12 to 24 hours of admission to minimize risk.1, 2 Consequently…
- Trial name
- NCT06729372
- Testing
- Deliberate Flawed Performance, Error Avoidance Training
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Pseudoarthrosis of Bone, Pseudarthrosis
Treatment of Nonunion Fractures With Mesenchymal Stromal Cells (MSCs)
The goal of this study is to evaluate the bone regeneration capacity of BM-MSC (Bone marrow mesenchymal stromal cells), in patients with nonunion.
- Conditions
- Pseudoarthrosis of Bone, Pseudarthrosis, Non Union Fracture, Nonunion Bone Fracture
- Trial name
- MSC (NCT06103396)
- Testing
- Transplantation of autologous MSCs in nonunion fracture, Transplantation of allogeneic MSCs in nonunion fracture
- Where
- Venezuela
- Volunteers
- 30 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Deformity; Bone
Lateral Closing Wedge Osteotomy for Cubitus Varus Deformity in Children
Humeral osteotomy is the most effective method for evident cubitus varus correction in children. Several osteotomy methods and fixation materials have been developed in the past.
- Trial name
- NCT04423835
- Testing
- Paley's Principle osteotomy
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Mandibular Class Iv Fractures
Patient-Specific Guides vs. Classical Workflow in Class IV Mandibular Fracture Fixation
This study aims to overcome the limitations of current, standard approach of mandibular fracture reduction and fixation including improper alignment of segments, malocclusion, nerve affections and related teeth roots injury.
- Trial name
- NCT07153354
- Testing
- patient-specific screw holes locating surgical guide and pre-bent plates, 2 titanium per-bent mini plates
- Volunteers
- 20 people
- Sponsor
- Mohamed abdelsalam Gaber elkhouly
Tibial Fracture
Doppler Ultrasonography Evaluation of Tibial Fracture Site Vascularity
The purpose of this study is to evaluate the blood supply to patients that are suffering from fracture in the tibia by UltraSound Doppler.
- Trial name
- NCT00365573
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Hip Fracture of Intertrochanteric Type
Postoperative Analgesia With Local Infiltration After Hip Fracture Of Intertrochanteric Type
Reducing pain is an essential factor for early mobilization after osteosynthesis of intertrochanteric fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT01119209
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Fracture Arm
Treatment of Medial Humeral Epicondyle Fractures in Children With Absorbable Cartilage Nails
To compare surgical outcomes from medial epicondyle fracture fixation with absorbable cartilage nails to those from traditional Kirschner wire fixation.
- Trial name
- NCT03112447
- Testing
- absorbable cartilage nail, traditional Kirschner wires
- Volunteers
- 32 people
- Sponsor
- Children's Hospital of Chongqing Medical University