Clinical trials: Free Flaps
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Head and Neck Cancer, Free Flap
Head and Neck Quality of Life
This study examines the quality of life for patients after head and neck free flap reconstruction, both pre-operative and at least 1 year post-operative.
- Trial name
- NCT06756763
- Where
- Taiwan
- Volunteers
- 315 people
- Sponsor
- Chang Gung Memorial Hospital
Flap Monitoring
Free Flap Microcirculatory Monitoring Correlates to Free Flap Temperature Assessment
In case of free flap failure, time is of utmost importance as salvage rates have been reported to be inversely related to the time interval between the onset of ischemia and its clinical recognition.
- Trial name
- NCT01235299
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Oral Cancer
Lateral Arm Free Flap for Reconstruction of the Oral Cavity and Head and Neck Soft Tissue Defects.
The excision of oral cancers causes extensive impairment of the oral cavity soft tissue. Complete excision of the tumors is vital, and the reconstruction of the resected area influences not only the postoperative recovery period…
- Trial name
- NCT05296811
- Testing
- Lateral Arm Free Flap
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- hassan harby mohamed
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Trauma
Thoracodorsal Artery Perforator Flap Versus Conventional Free Flaps
The purpose of this study is to assess the efficacy of the thoracodorsal artery perforator flap versus other conventional free flaps for reconstruction of soft tissue defects.
- Trial name
- NCT03658603
- Testing
- thoracodorsal artery perforator flap, latissimus dorsi flap
- Volunteers
- 40 people
- Sponsor
- Assiut University
3d Printing, Facial Symmetry
Whole vs Segmented 3D Models for Mandibular Reconstruction
Three-dimensional (3D) printing is increasingly used in surgery to help doctors plan and perform complex operations with greater accuracy.
- Conditions
- 3d Printing, Facial Symmetry, Free Fibular Flap, 3d Model
- Trial name
- NCT07365085
- Testing
- 3D-printed surgical guide - segmented model, 3D-printed surgical guide - whole mandible model
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Indonesia
Tongue Squamous Cell Carcinoma, Mixed Reality
Resection and Defect Repair of Oral Cancer Aided by Mixed Reality Technology
The objective of this exploratory clinical trial is to apply Unreal Engine 5 (UE5)-based Mixed Reality (MR) technology to achieve real-time stereoscopic visualization of surgical planning, personalized free flap harvest and…
- Conditions
- Tongue Squamous Cell Carcinoma, Mixed Reality, Virtual Surgical Planning, Free Flap
- Trial name
- NCT07466810
- Testing
- Unreal Engine 5 (UE5)-based Mixed Reality (MR) Technology-assisted Resection of Oral Cancer and Defect Reconstruction, Virtual Surgical Guide Technology-assisted Resection of Oral Cancer and Defect Reconstruction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Meningocele, Meningomyelocele
Propellers Flaps for Meningomylocele Defects
To evaluate reliability of free style propeller perforator flap for coverage MMC soft tissue defect follow a well-established step that overcome the usual problem of pedicled perforators propellers flaps.
- Trial name
- NCT05188300
- Testing
- Freestyle pedicled perforators propellers flaps for meningomyelocele defects
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Mandible Reconstruction
Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction
The study aims to evaluate facial symmetry outcomes after mandibular reconstruction using fibula free flaps, comparing two fixation techniques: the prosthetically favorable position (alveolar level) and the conventional position…
- Trial name
- NCT06790628
- Testing
- Fibula free flap
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Flap Necrosis
Lateral Arm Flap Usage as Pedicle and Free Flap
Abstract Introduction For local reconstruction on upper extremity or as a distant micro vascular flap Lateral arm free flap is an excellent source of tissue with the advantages including short operation time, thin pliable tissue…
- Trial name
- NCT03763383
- Testing
- Lateral Arm Flap
- Where
- Pakistan
- Volunteers
- 21 people
- Sponsor
- Aga Khan University
Hemifacial Atrophy
Two- and Three-Dimensional Quantification of Facial Symmetry After Fat Grafting and Free Flap Reconstruction in Hemifacial Atrophy
Hemifacial atrophy causes one side of the face to become smaller, leading to facial asymmetry. Surgeons often restore facial volume using either autologous fat grafting or free-flap reconstruction.
- Trial name
- NCT07305909
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College
Mandible Reconstruction
Comparaison of the Accuracy of Immediate Fibula Reconstruction With Implants in Fresh Versus Delayed Cases
The goal of this clinical trial is to learn if mandibular reconstruction with immediate dental implants is as accurate in fresh cases and delayed cases The accuracy of the fibular segments and dental implants will be compared in…
- Trial name
- NCT07452315
- Testing
- fibula free flap
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
CSF Leakage
Free Middle Turbinate Flap for Repair of Low Flow Cerebrospinal Fluid Leak
Limited literature has been reported the use of free middle turbinate flap during an endoscopic approach to treat cerebrospinal fluid (CSF) leak, and the results were inconclusive.
- Trial name
- NCT04784169
- Testing
- free middle turbinate flap, vascularized nasoseptal flap
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Oral Tumor
Vascularized Free Fibula Flap and Computer-guided Implant Surgery
The rehabilitation of patients affected by defects of the jaws after tumor resection is still very challenging. Resection can lead to significant facial deformity, impaired oral functions such as speech, swallowing, saliva…
- Trial name
- NCT01561534
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Bari
Maxillary Neoplasms
Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps
Bony reconstruction of the midface with free tissue transfer is complex and challenging due to structural considerations such as the need for orbital support, patency of the nasal cavity, restoration of the palate and alveolus…
- Trial name
- NCT04522700
- Testing
- scapular free flap
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- hassan harby mohamed
Free Flap Evaluation, Indocyanine Green Concentration
Diluted Indocyanine Green Angiography: a Novel Approach to Free Flap Perfusion Evaluation in Reconstructive Microsurgery
The evaluation of perfusion in free flaps is crucial in clinical practice. Currently, the gold standard for evaluation is subjective through clinical assessment.
- Conditions
- Free Flap Evaluation, Indocyanine Green Concentration, Perfusion
- Trial name
- NCT06220357
- Testing
- Indocyanine Green
- Where
- Indonesia
- Volunteers
- 47 people
- Sponsor
- Universitas Indonesia
Maxillary Tumors
Aesthetic Reconstruction of Onco-surgical Maxillary Defects Using FSF With and Without CAD/CAM Customized Cutting Guide
The aim of the study is to compare aesthetic results and operation time of Free Scapular flap with and without CAD/CAM customized osteotomy guide for reconstruction of maxillary Defects.
- Trial name
- NCT03757286
- Testing
- FSF with CAD\CAM customized cutting guide, FSF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Head Neck Neoplasms
Recipient Vessels for Free Tissue Flaps in Advanced Oncologic Defects of the Midface and Scalp
The goal of this clinical trial is to compare the postoperative outcomes based on superficial temporal versus cervical recipient vessels for midface and scalp advanced oncologic defects using free tissue flap for reconstruction.
- Trial name
- NCT05749120
- Testing
- Recipient vessel selected for microanastomosis
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto Nacional de Cancer, Brazil