Clinical trials: Fulminant Hepatic Failure
Fulminant Liver Failure
Hepatocyte Transplantation as a Life Support Bridge
The purpose of this study is to gain knowledge about the result of infusing liver cells, carefully matched to blood type, into a subject's body.
- Trial name
- NCT00282542
- Testing
- Hepatocyte Infusion
- Sponsor
- Virginia Commonwealth University
Acute Liver Failure
Etiology and Prognostic Factors in Patients With Acute Liver Failure
Acute liver failure (ALF) is a rare but life-threatening condition with high mortality. Despite advances in supportive care and liver transplantation, prognosis varies significantly across etiologies, particularly in patients…
- Trial name
- NCT07556055
- Volunteers
- 400 people
- Sponsor
- Li-Ying Sun
Hepatitis B, Cirrhosis
Prevention of Recurrent Hepatitis B After Liver Transplantation
Hepatitis B accounts for approximately 5000 deaths per year in the United States. Liver transplantation offers the only hope for patients who develop end-stage liver disease.
- Conditions
- Hepatitis B, Cirrhosis, Acute Liver Failure, Hepatocellular Carcinoma
- Trial name
- NCT00059267
- Testing
- HBIG, Epivir, Hepsera
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Acute Liver Failure
Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver Failure
The purpose of the study is to determine whether L-Ornithine L-Aspartate infusion improves the survival of patients with acute liver failure.
- Trial name
- NCT00470314
- Testing
- L-Ornithine L-Aspartate
- Where
- India
- Volunteers
- 150 people
- Sponsor
- All India Institute of Medical Sciences
Acute Liver Failure
High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure
The study will be conducted on patients admitted to Department of Hepatology from Jan 2016 to Jan 2018 at Institute of Liver \& Biliary Sciences, New Delhi.
- Trial name
- NCT02718079
- Testing
- Plasma Exchange, Management of cerebral edema/intracranial hypertension:, Transfer to Intensive Care Unit
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Liver Failure, Acute
Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure
The purpose of this study is to determine whether recombinant human hepatocyte growth factor is safe and effective in the treatment of fulminant and late-onset hepatic failure.
- Trial name
- NCT00225901
- Testing
- Recombinant human hepatocyte growth factor
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Acute Liver Failure
Emergency Use of OCR-002 in Acute Liver Failure (ALF)
This study provides emergency use of the unapproved study medication in ALF patients with acute liver failure who are not responding to standard of care.
- Trial name
- NCT01634230
- Testing
- OCR-002
- Where
- United States
- Sponsor
- Ocera Therapeutics, Inc.
End Stage Liver Disease, Acute Liver Failure
Robotic vs. Laparoscopic vs. Open Living Donor Hepatectomy
This will be a study to examine the outcomes of open, laparoscopic, and robotic Living Donor Liver Transplantation (LDLT) procedures.
- Conditions
- End Stage Liver Disease, Acute Liver Failure, Acute-On-Chronic Liver Failure, Hepatocellular Carcinoma
- Trial name
- NCT06062706
- Testing
- Donor hepatectomy
- Where
- Saudi Arabia
- Volunteers
- 3,448 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Acute Liver Failure, Hepatic Encephalopathy
A Multi-Center Group to Study Acute Liver Failure in Children
The PALF study group began with 20 sites and now continues with 12 sites (11 in the United States and 1 in Canada) in the new funding period.
- Trial name
- NCT00986648
- Where
- 20 sites in United States, Canada and 1 more
- Volunteers
- 158 people
- Sponsor
- University of Pittsburgh
Acute Liver Failure, Acute Liver Injury
Biomarkers in Liver Failure
Acute liver injury (ALI) and acute liver failure (ALF) are rare clinical conditions, the latter often associated with a poor outcome.
- Conditions
- Acute Liver Failure, Acute Liver Injury, Acute on Chronic Hepatic Failure
- Trial name
- NCT02833064
- Testing
- Non-contrast magnetic resonance imaging, Biological sampling
- Volunteers
- 200 people
- Sponsor
- University of Edinburgh
Biliary Atresia, Metabolic Disorders
Clinical and Basic Study for Pediatric Liver Transplantation
Background: In mainland China, the development of pediatric liver transplantation (LT) has lagged behind that of adult LT during the past two decades, but it has been progressing immensely in recent years.
- Conditions
- Biliary Atresia, Metabolic Disorders, Fulminant Liver Failure, Hepatic Tumors
- Trial name
- CBSPLT (NCT02503384)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Acute Liver Failure
Hepatocyte Microbeads for Acute Liver Failure
Acute Liver Failure in children is associated with high mortality without liver transplantation. In addition, donor organ shortage makes it difficult to provide this treatment to every potential patient.
- Trial name
- HELP (NCT05491135)
- Testing
- HMB002
- Volunteers
- 17 people
- Sponsor
- King's College Hospital NHS Trust
Liver Failure Acute
Hepatocyte Transplantation for Acute Decompensated Liver Failure
The purpose of this research study is to determine whether liver cell transplantation can provide help for patients with liver failure who are unlikely to survive without some form of liver support.
- Trial name
- NCT01345565
- Testing
- human hepatocytes
- Where
- United States
- Sponsor
- Ira Fox
Fulminating Hepatic Failure
Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris
The main objective is to determine the medical fate (transplanted or not and living or deceased), of patients with Severe, fulminating acute liver failure in the public hospitals of paris.
- Trial name
- DEVINHEF (NCT04658407)
- Where
- France
- Volunteers
- 18,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris