Clinical trials: Functional Abdominal Pain Syndrome
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Functional Abdominal Pain Syndrome
ICBT for Children With FAPDs - the Child's Pain Regulation
Functional abdominal pain disorders (FAPDs) in children are common (14%) and abdominal pain has increased rapidly in children during the last ten years in Sweden.
- Trial name
- NCT05945251
- Testing
- Internet-delivered cognitive behavioral therapy
- Where
- Sweden
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Functional Abdominal Pain Syndrome, Anxiety
Improving Care for Youth With FAP: A Stepped Care CBT Delivery Approach
This project aims to test a stepped care behavioral intervention approach for youth with functional abdominal pain (FAP) that is feasible to administer in medical settings. Screening and a brief intervention (i.e.
- Trial name
- NCT03134950
- Testing
- ADAPT
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Michigan State University
Stress, Irritable Bowel Syndrome
Evaluating and Treating Potential Research Participants With Digestive Disorders
Background: Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these…
- Conditions
- Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain
- Trial name
- NCT01736280
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Does Improving Vagal Tone Increase Mitochondrial Bioenergetics
This study evaluates the effect of auricular neurostimulation on mitochondrial bioenergetics and inflammation through vagal nerve modulation via non-invasive percutaneous electrical nerve field stimulator in children with…
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain Syndrome
- Trial name
- NCT03931330
- Testing
- Percutaneous neurostimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Irritable Bowel Syndrome, Abdominal Pain
Delivered Dietary Intervention for Children With Irritable Bowel Syndrome
The purpose of this study is to determine whether a specific diet may help children with irritable bowel syndrome.
- Trial name
- NCT01339117
- Testing
- Low fermentable substrate diet, High fermentable substrate diet
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Functional Abdominal Pain, Functional Dyspepsia
Efficacy of Open Label Placebo in Children With FGIDs
This study is aimed at investigating the efficacy of placebo for symptom relief in children with abdominal pain related functional gastrointestinal disorders.
- Conditions
- Functional Abdominal Pain, Functional Dyspepsia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- Placebo (NCT02389998)
- Testing
- Hyoscyamine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Children's Hospital
Self-hypnosis, Functional Bowel Disorder
Hypnotherapy With Audiofiles for Children and Adolescents With Disorders of Gut-brain Interactions in Sweden -a Feasibility Study
This study aims at testing the effect and feasibility of a new treatment strategy - hypnotherapy mediated with audio files - for children and adolescents with disorders of gut-brain-interaction (DGBI) in Sweden.
- Conditions
- Self-hypnosis, Functional Bowel Disorder, Functional Abdominal Pain Syndrome
- Trial name
- NCT06493097
- Testing
- Gut-directed hypnotherapy via audio files
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Abdominal Pain, Functional Gastrointestinal Disorders
Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders
The purpose of this study is to: 1. Determine if audio recorded guided imagery vs deep breathing exercises delivered via a digital media player improves abdominal pain symptoms in children with functional gastrointestinal pain…
- Trial name
- NCT03100487
- Testing
- Apple iPod Shuffle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Baylor College of Medicine
Functional Abdominal Pain Disorder
Low-FODMAP Diet for Functional Abdominal Pain Disorders in Children.
This single-center, randomized, controlled, quadruple-blinded, superiority trial is performed to test the hypothesis that children with IBS and FAP-NOS who receive a low-FODMAP diet will have a lower mean abdominal pain intensity…
- Trial name
- NCT04528914
- Testing
- Low-FODMAP diet
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Medical University of Warsaw
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study
Peppermint oil has shown to be effective in the treatment of Irritable Bowel Syndrome (IBS) symptoms in adults. Few studies of low quality are performed in an paediatric setting.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Child, Adolescent
- Trial name
- MINT (NCT05799053)
- Testing
- Small intestinal release peppermint oil, Peppermint sweets
- Where
- 3 sites in Netherlands
- Volunteers
- 228 people
- Sponsor
- St. Antonius Hospital
Functional Abdominal Pain Syndrome
Therapeutic Effect of the Low FODMAP Diet in Children With Functional Abdominal Pain.
Diet components are important factors in pathogenesis of functional gastrointestinal disorders, especially in the irritable bowel syndrome.
- Trial name
- NCT03771027
- Testing
- The low FODMAP diet., The diet based on NICE guidelines.
- Where
- 2 sites in Poland
- Volunteers
- 33 people
- Sponsor
- University of Warmia and Mazury
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Functional Abdominal Pain Syndrome
Brain Mechanisms of Attention and Pain in Youth With FAPD
The objectives of this study are to identify neural mechanisms of increased pain in pediatric FAPD and examine mechanisms of disrupted attention in the presence of induced pain.
- Trial name
- NCT05892055
- Testing
- MRI Procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michigan State University
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Functional Abdominal Pain Disorders
Internet-Delivered CBT for Children With Functional Abdominal Pain Disorders
This randomized controlled study aims to evaluate the efficacy of exposure-based Internet-delivered cognitive behavior therapy for children 8-12 years with Functional Abdominal Pain Disorders.
- Trial name
- NCT02873078
- Testing
- Internet-delivered Cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome, Gluten Sensitivity
Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics.
Recently a new clinical entity, gluten sensitivity (GS), a form of gluten intolerance in which neither allergic nor autoimmune mechanisms can be identified, has been added to the spectrum of gluten-related disorders.
- Trial name
- GS-IBS (NCT02431585)
- Testing
- gluten
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati