Clinical trials: Functional Disorder
Fabry Disease
Registry of Fabry Disease - A Multicenter Observational Study
The purpose of this study is to compile a registry of patients with Fabry disease, an inherited metabolic disorder. In this disease, an enzyme called a-galactosidase A, which normally breaks down a lipid (fatty substance) called…
- Trial name
- NCT00055016
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury, Subarachnoid Hemorrhage
Pituitary Functions After Traumatic Brain Injury (TBI) and/or Subarachnoid Hemorrhage (SAH)
This study performs assessments of pituitary functions by basal hormone levels in the acute phase after TBI and/or SAH followed by detailed endocrine tests (insulin-induced hypoglycemia or growth hormone releasing…
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Hypopituitarism
- Trial name
- NCT00507104
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Down Syndrome
Effect of Sensory Integration on Gross and Balance on Children With Down Syndrome
To investigate the effect of sensory integration on gross motor function in children with Down syndrome. To investigate the effect of sensory integration on balance in children with Down syndrome.
- Trial name
- NCT07785011
- Testing
- BALANCE AND SENSORY INTEGRATION
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Raheel Sanad
Adolescent Idiopathic Scoliosis (AIS), Scoliosis; Adolescence
Effects of Expiratory Muscle Strength Training in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis result in deterioration of core muscles and respiratory system. Core muscles provide trunk stabilization as well as responsible for respiratory system. Especially tr.
- Trial name
- NCT06752993
- Testing
- Expiratory Muscle Strength Training (EMST-150)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Autism Spectrum Disorder, Autism
Music for Autism (M4A)
The Music for Autism (M4A) trial evaluates the neurobehavioral outcomes of a music therapy (MT) intervention, compared to a matched play therapy (PT) intervention, on social communication skills, brain connectivity and structural…
- Trial name
- M4A (NCT04936048)
- Testing
- Music Therapy, Play therapy
- Where
- 2 sites in Austria, Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS
Sickle Cell Disease
Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive Functioning
Sickle cell disease (SCD) necessitates a paediatric treatment plan that considers the influence of psychological, family and intercultural factors.
- Trial name
- NCT03975699
- Testing
- Assessment of psychological repercussions of SCD
- Volunteers
- 155 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Child, Abdominal Pain
Abdominal Pain Disorders Functional in Children: Impact of Hypno-analgesia on the Autonomic Balance
Abdominal pain disorders functional (including functional dyspepsia, irritable bowel syndrome, abdominal migraine, functional abdominal pain) is a very common disease in the pediatric population, where classical medical treatment…
- Trial name
- NCT02830698
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Autism Spectrum Disorder
Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
The aim of the study is to determine the effects of usage of augmented reality for Restricted and repetitive behavior and executive function of children with autism spectrum disorder
- Trial name
- NCT05962047
- Testing
- Games of WonderTree Augmented Reality, Traditional therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Primary Ciliary Dyskinesia
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype
The purpose of this study is to measure mucociliary clearance (MCC) in groups of subjects with the disease Primary Ciliary Dyskinesia (PCD) caused by mutations in different genes, and compare to healthy subjects.
- Trial name
- NCT04901715
- Testing
- Albuterol, Technetium99m - Sulfur Colloid (Tc99m-SC)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cerebral Palsy, Dystonia
Whole Body Vibration for Dystonia Cerebral Palsy
Health bones allow us to move and walk freely without pain. Physical activities have been shown to relate to healthy bone growth.
- Trial name
- WBVT (NCT03779308)
- Testing
- whole body vibration therapy
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The Hong Kong Polytechnic University
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma in Children, Telerehabilitation
COVID-19 Pandemic Asthma Child Telerehabilitation Yoga
In our study, yoga asana and pranayama practices, which will be applied by video call from computer or phone, will be advantageous in terms of time, transportation and access to asthmatic children whose anxiety and anxiety levels…
- Conditions
- Asthma in Children, Telerehabilitation, Yoga
- Trial name
- NCT05684926
- Testing
- Telerehabilitation yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bartın Unıversity
Brain Tumor, Pediatric Brain Tumor
Understanding the Late Effects of Surviving a Pediatric Brain Tumor
The goal of this study is to learn about the cognitive and behavioral functioning of children being treated for cancer.
- Conditions
- Brain Tumor, Pediatric Brain Tumor, Pediatric Cancer
- Trial name
- NCT03208387
- Testing
- Diffusion tensor imaging (DTI), Resting state functional connectivity MRI (rs-fcMRI), Wechsler Intelligence Scale for Children - 5th edition (WISC-V)
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Celiac Disease, Irritable Bowel Syndrome
Irritable Bowel Syndrome Overlaping Celiac Disease
The goal of this prospective observational cohort stuty is to assess the prevalence of overlap irritable bowel syndrome on coeliac disease in patients on gluten-free diet.
- Conditions
- Celiac Disease, Irritable Bowel Syndrome, Overlap Syndrome
- Trial name
- IBSonCD (NCT05740306)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Centre of Postgraduate Medical Education
Postoperative; Dysfunction Following Cardiac Surgery, Postoperative; Dysfunction Following Lung Surgery
Comparison of Two Modes of Respiratory Physiotherapy in Cardio-thoracic Surgical Patients
Two forms of pre and postoperative physiotherapy are compared in three cohorts of patients undergoing cardio-thoracic surgery: Minor thoracic surgery (biopsy), major thoracic surgery (lobectomy etc, open or VATS) and cardiac…
- Trial name
- NCT02931617
- Testing
- Chest Physiotherapy, Post-therapy lung volume measurements
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University Hospital
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal Transcranial Direct Current Stimulation in Adolescents With ASD
Autism spectrum disorder (ASD) is a pervasive and lifelong developmental disorder that currently affects 1 in 54 children. Individuals with autism are often severely impaired in communication, social skills, and cognitive…
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography, Booster Effects
- Trial name
- NCT05492032
- Testing
- Active-tDCS, Cognitive training
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University
Executive Function of School-aged Children With ASD
VR Executive Training of School-aged Children With ASD
Many studies support that children with autism spectrum disorder (ASD) show executive dysfunction. The applicant's NSC project report also indicated that in all areas in the behavior rating inventory of executive function, the…
- Trial name
- NCT06130293
- Testing
- VR game intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan Normal University
Type 1 Diabetes
Investigation of the Skin Barrier in Patients With Type 1 Diabetes
This study is a case-control study comparing the skin barrier between 50 T1D patients with healthy controls in 3 age-strata including both pediatric and adult patients.
- Trial name
- NCT04280315
- Where
- 2 sites in Denmark
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Jannet Svensson
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