Clinical trials: Functional Disorder of Intestine
Refractory Constipation, Fecal Incontinence in Children
The Role of Anorectal Manometry in Pediatric Chronic Refractory Constipation
This research protocol outlines a two-year descriptive cross-sectional study to investigate the role of high-resolution anorectal manometry (HRAM) in children aged 4-18 years with chronic refractory constipation.The study plans…
- Trial name
- NCT07291661
- Testing
- High resolution anorectal manometry using a multiuse water perfused catheter
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
Internet-delivered Cognitive Behavior Therapy for Adolescents With Functional Gastrointestinal Disorders: a Pilot Study
This pilot-study aims to evaluate the treatment effects and feasibility of an internet-delivered CBT-program for adolescents with functional gastrointestinal disorders.
- Trial name
- NCT02033161
- Testing
- Internet-delivered CBT
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome, Children
Immunological Change and the Single Nucleotide Polymorphism (SNP) in Children With Irritable Bowel Syndrome (IBS)
Currently, the pathophysiology of Irritable bowel syndrome( IBS) remains unclear . The purpose of this study is want to investigate the immunological changes in the children with IBS.
- Trial name
- NCT01131442
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Inflammatory Bowel Disease
Immune Function in Offsprings of Females With Inflammatory Bowel Disease
1. To evaluate the immune response to vaccines in infants of IBD patients treated with anti-TNF medications during pregnancy compared to infants of IBD mother not treated with anti-TNF medications. 2.
- Trial name
- NCT02079441
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Irritable Bowel Syndrome
Effectiveness of Probiotics Stabilized With Cryoprotection Technology in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is one of the most common diseases of the digestive tract in adults, which pathogenesis is not fully understood.
- Trial name
- NCT04206410
- Testing
- Probiotic, Maltodextrin
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Children's Memorial Health Institute, Poland
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Irritable Bowel Syndrome, Abdominal Pain
Mobile Self-Management of Irritable Bowel Syndrome for Adolescents
The objective of the proposed research is to conduct user testing of a mobile-based self-management support intervention for adolescents and young adults with Irritable Bowel Syndrome (IBS), a chronic digestive condition.
- Trial name
- NCT03138980
- Testing
- BodiMojo Buddy for IBS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Mullerian Anomaly of Vagina, Mullerian Anomaly of Uterus, Nec
Diagnostic, Therapeutic and Reproductive Aspects of Patients With Mullerian Anomalies (MULAN)
The purpose of this study is to get a better understanding of the clinical implications (including reproductive problems and obstetric complications), appropriate diagnostic tools and correct surgical treatment of Mullerian…
- Conditions
- Mullerian Anomaly of Vagina, Mullerian Anomaly of Uterus, Nec, Mullerian Anomaly of Cervix
- Trial name
- MULAN (NCT04732546)
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Irritable Bowel Syndrome
Efficacy of Probaclac in Irritable Bowel Syndrome in Children Aged 8 to 18 Years
The aim of this study is to determine the efficacy of the administration of Bifidobacterium bifidum R0071, Bifidobacterium longum R0175, Lactobacillus helveticus R0052, Lactobacillus Delb.
- Trial name
- POPSII (NCT00793494)
- Testing
- Probaclac
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- St. Justine's Hospital
Irritable Bowel Syndrome (IBS)
Microbiome Fructan Metabolism and Symptoms in Childhood IBS
This study evaluates whether the gut microbiome is involved in determining whether children with irritable bowel syndrome (IBS) develop worsening GI symptoms (e.g. pain) when given fructans (a sugar often found in wheat).
- Trial name
- NCT02842281
- Testing
- Fructan, Maltodextrin
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Functional Abdominal Pain Syndrome
Reducing Pain and Anxiety Through Dietary Fiber Supplementation in Children With Abdominal Pain
Background - Mental health and pain problems in early childhood are major risk factors for serious mental health problems into adulthood.
- Trial name
- NCT04619095
- Testing
- Psyllium
- Where
- Canada
- Sponsor
- University of Calgary
Graft Vs Host Disease, Inflammatory Bowel Diseases
Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)
The goal of the Precision Diagnosis in Inflammatory Bowel Disease, Cellular Therapies, and Transplantation (PREDICT) trial is to apply a systems-biology approach to enable precision diagnostics for the key immunologic outcomes…
- Conditions
- Graft Vs Host Disease, Inflammatory Bowel Diseases, Functional Gastrointestinal Disorders
- Trial name
- PREDICT (NCT03369353)
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Boston Children's Hospital
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Irritable Bowel Syndrome
Psyllium in Pediatric IBS
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating…
- Trial name
- Psyllium (NCT06639984)
- Testing
- Psyllium (0.7 g/year of age per day), Psyllium (0.5 g/year of age per day), fructans
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Dr Bruno Chumpitazi, M.D.
Irritable Bowel Syndrome (IBS)
Collaborative Cognitive Behavioral Therapy / Hypnotherapy for Treatment of Pediatric Functional Gastrointestinal Disease
This program has been created to help patients with irritable bowel syndrome manage their symptoms and increase their functioning by using cognitive therapy skills and hypnosis.
- Trial name
- CAPP (NCT01966341)
- Testing
- CBT/ Hypnotherapy, Routine Management
- Where
- United States
- Sponsor
- Seton Healthcare Family
Irritable Bowel Syndrome
Dieta Mediterranea e Sindrome Dell'Intestino Irritabile in Pazienti Pediatrici
The goal of this observational study is to observe pediatric patients with IBS (irritable bowel syndrome). The main question it aims to answer are: adherence to the Mediterranean diet of children with IBS in patients not adhering…
- Trial name
- NCT05738343
- Testing
- dieta mediterranea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
CHAPLE Disease
A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease
This study is researching a drug called pozelimab (called "study drug"). The main aim of this study is to monitor the safety and tolerability of the study drug.
- Trial name
- NCT07142343
- Testing
- Pozelimab
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people
- Sponsor
- Regeneron Pharmaceuticals
Inflammatory Bowel Diseases
Genetic an Functional Studies of Patient With Inflammatory Bowel Disease
The objective of this study is to study the response of macrophages, isolated from patients with ulcerative colitis (Crohn's disease) or Crohn's disease (CD), to 6 candidate enterogenous and their derivatives, depending on the…
- Trial name
- MINOTOR (NCT03751722)
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Lille
Cystic Fibrosis
Gut Imaging for Function & Transit in Cystic Fibrosis Study 2
People with Cystic Fibrosis (CF) have problems digesting their food properly. More than 8 in 10 people with CF must take medication to assist their digestion. In spite of this, complications such as bowel blockage occur.
- Trial name
- GIFT-CF2 (NCT04006873)
- Testing
- Tezacaftor/Ivacaftor + Ivacaftor
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Fecal Calprotectin Collection Protocol
The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study.
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Ulcerative Colitis, Crohn Disease
- Trial name
- CALFE (NCT03143517)
- Testing
- Stool collection
- Where
- 13 sites in United States
- Volunteers
- 240 people
- Sponsor
- DiaSorin Inc.