Clinical trials: Functional Disturbance
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism Spectrum Disorder, Emotional Regulation
Effectiveness of Robot-Assisted Intervention and Sensory Integration Therapy in Enhancing Social-Emotional Skills in Children With Autism
This study is designed to evaluate and compare the impact of robot-assisted intervention using a smart robot (Kebbi Air) and traditional sensory integration therapy on improving social-emotional skills in children diagnosed with…
- Conditions
- Autism Spectrum Disorder, Emotional Regulation, Sensory Integration Dysfunction
- Trial name
- NCT06757673
- Testing
- Robot-Assisted Therapy using Kebbi Air, Sensory Integration Therapy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Immune Thrombocytopenia, Thrombotic Thrombocytopenic Purpura
Longitudinal Cohort of Thrombosis and Hemostasis Diseases
This is a multicenter, prospective, longitudinal, observational cohort study to investigate thrombosis and hemostasis diseases in Chinese patients.
- Conditions
- Immune Thrombocytopenia, Thrombotic Thrombocytopenic Purpura, Hemophilia A, Acquired, Disseminated Intravascular Coagulation
- Trial name
- NCT06727669
- Where
- 5 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Somatic Dysfunction of Cranial Region, Somatic Dysfunction of Cervical Spine
Newborn Cranial Somatic Dysfunction - An Observational Study
Two prominent osteopathic physician researchers have studied cranial somatic dysfunction in newborns. Dr Viola Frymann published a paper in 1966 on the presence of somatic dysfunction involving 1250 infants. Dr.
- Conditions
- Somatic Dysfunction of Cranial Region, Somatic Dysfunction of Cervical Spine, Somatic Dysfunction of Lumbar Spine, Somatic Dysfunction of Sacrum
- Trial name
- NCT01496872
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- A.T. Still University of Health Sciences
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cerebral Palsy, Sensation Disorders
Upper Extremity Sensation and Function in Children With Cerebral Palsy
This cross-sectional study was designed to evaluate upper extremity sensation in children with spastic cerebral palsy and to investigate its effect on upper extremity use in activities of daily living.
- Conditions
- Cerebral Palsy, Sensation Disorders, Upper Extremity Dysfunction
- Trial name
- NCT07352735
- Testing
- Vibration Sense Assessment, Stereognosis, Tactile Sense
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
STEMI
Erectile Dysfunction After Percutaneous Coronary Intervention Versus the Thrombolytic Therapy in Acute ST Elevation Myocardial Infarction
Erectile dysfunction is a common sexual problem affecting up to one-third of men throughout their life. It is now well recognized that risk factors for erectile dysfunction (ED) include the same risk factors as coronary artery…
- Trial name
- NCT03328156
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Syndrome X
Syndrome X and Endothelial Dysfunction
Cardiac syndrome X is characterized by angina, positve stress test, and patent coronary angiography, and its probable mechanism is microvascular dysfunction associated with endothelial dysfunction.
- Trial name
- NCT00190086
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Attention Deficit Hyperactivity Disorder
Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder
The present project is to identify the relationship between ADHD and the metabolites of tryptophan.
- Trial name
- NCT03901859
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Renal Insufficiency, Chronic
Explore New Magnetic Resonance Technology in Assessment of Renal Dysfunction
Currently, renal biopsy is the gold standard for evaluating renal pathology and renal fibrosis, but it is invasive and carries the risk of serious complications; and the sampled tissue is only a small part of the kidney, which is…
- Trial name
- NCT06366529
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhen Li
Lower Urinary Track Symptoms
Urinary CA19-9 Level in the Differential Diagnosis of Neurogenic and Non-Neurogenic Lower Urinary Tract Dysfunction in Children
It has been shown in the literature that urinary CA19-9 levels are associated with the degree of hydronephrosis and the anteroposterior diameter of the renal pelvis.
- Trial name
- NCT06785545
- Testing
- CA19-9
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Systemic Sclerosis
Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension
Although the aetiology of SSc-PAH remains elusive, vascular dysfunction seems to be the initial event and statins through their vasculoprotective effect might be of value in the treatment armamentarium of PAH related to SSc.
- Trial name
- NCT00984932
- Testing
- Rosuvastatin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Pelvic Floor, Female Athletes
Pelvic Floor Knowledge and Dysfunction in Female Athletes
The pelvic floor is a complex structure composed of bones, connective tissue, muscles, and nerves that supports the pelvic organs and provides voluntary control and resting tone of the sphincters.
- Conditions
- Pelvic Floor, Female Athletes, Physical Activity, Demographic Data
- Trial name
- NCT07209839
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Berivan Beril Kılıç
Schizophrenia, Cognitive Impairment
From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia
The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia.
- Conditions
- Schizophrenia, Cognitive Impairment, Social Competence
- Trial name
- ecoval (NCT03543553)
- Testing
- This is not an intervention study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Spinal Cord Injury
The Effect of FES on Children With Spinal Cord Injury
Regular exercise is strongly recommended to help maintain a healthy lifestyle. Unfortunately, children and young adults with damaged spinal cords may not be able to exercise regularly.
- Trial name
- NCT00291317
- Testing
- RT 300-P FES Cycle
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's Specialized Hospital
Down Syndrome, Polyendocrinopathies, Autoimmune
Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
This study plans to learn more about Down syndrome. The investigators think there is a different level of the AIRE gene in individuals with Down syndrome.
- Conditions
- Down Syndrome, Polyendocrinopathies, Autoimmune, Respiratory Tract Infections, Autoimmunity
- Trial name
- NCT02421276
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Lower Urinary Tract Disorder
Pelvic Floor Muscle Activity, Respiratory Functions, Respiratory Muscle Strength, and Functional Capacity in Children With Lower Urinary Tract Dysfunction
The functional disorders of the lower urinary tract in children involve overactive bladder with thickening of the bladder muscle, resulting in a decrease in functional bladder volume and an increase in intra-bladder pressure.
- Trial name
- NCT06652178
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Breastfeeding
Efficacy of an Osteopathic Treatment for Mechanical Sucking Dysfunctions in Newborn
Breastfeeding is the physiological and recommended way of feeding newborns as indicated by the World Health Organization, Health Canada and the politics of perinatality 2008-2018 in Quebec.
- Trial name
- NCT02407860
- Testing
- osteopathic treatment, usual breastfeeding counselling
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Executive Dysfunction, Physical Stress
Integrative Adolescence Research Programme (IARP)
This study aims to understand child health during adolescence. We will examine the role of lifestyle (e.g. physical activity), growth trajectories and other environmental factors that can influence the development of phenotypes…
- Conditions
- Executive Dysfunction, Physical Stress, Mental Health Wellness 1
- Trial name
- IARP (NCT06622681)
- Testing
- No intervention
- Where
- 2 sites in Singapore
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore