Clinical trials: Functional Independence
Spastic Cerebral Palsy (sCP)
Bimanual Training Versus Unilateral Task Specific Training in Children With Spastic Hemiplegic Cerebral Palsy
Cerebral palsy is one of the most common childhood neurological disorders and often results in weakness, poor coordination, and stiffness (spasticity) in one side of the body in children with spastic hemiplegic cerebral palsy.
- Trial name
- BUST-CP (NCT07437274)
- Testing
- Bimanual Training, Unilateral Task-Specific Training
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Montiha Azeem
Neurofibromatosis 1 (NF1), Executive Function (Cognition)
Cognitive Intervention for Children and Adolescents With NF1
Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations.
- Conditions
- Neurofibromatosis 1 (NF1), Executive Function (Cognition), Cognitive Intervention
- Trial name
- NCT07869914
- Testing
- Unstuck and On Target!
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Traumatic Brain Injury
Impact of Traumatic Brain Injury on Cognitive Function, Balance and Functional Independence in Children
The purpose of the study is to determine the impact of different levels of traumatic brain injury on cognitive function, functional independence and balance on children and relation of cognitive dysfunction, balance disturbance…
- Trial name
- Impact TBI (NCT07612410)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Activities of Daily Living, Hospitalization
Independence in Self Care - A Program Focused on Nursing Care
This study is a randomized clinical trial conducted in a medical ward of an acute 580-bedded teaching hospital. One hundred fifty-eight older acute medical patients will be blindly randomly allocated to the control group or…
- Conditions
- Activities of Daily Living, Hospitalization, Nursing Care, Functional Impairment
- Trial name
- NCT03106064
- Testing
- Promoting independence in self-care, Usual Care
- Where
- Portugal
- Volunteers
- 158 people
- Sponsor
- Centro Hospitalar do Porto
Amputation, Functional Limitation
Impact Evaluation of Breizh Fabribus Intervention for Personalized Assistive Technology Creation or Adaptation
In France, more than 14 million individuals report severe functional limitations, and nearly 5 million struggle with essential daily activities.
- Conditions
- Amputation, Functional Limitation, Autonomy of Older People, Handicaps Physical
- Trial name
- BFB-IMPACT (NCT07314099)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fondation Ildys
Hemophilia, Hemophilia A, Severe
Reliability and Validity of the Turkish Version of the PedHAL
This study aimed to establish the validity and reliability of the Turkish version of the Pediatric Haemophilia Activities List (short - PedHALshort) questionnaire.
- Conditions
- Hemophilia, Hemophilia A, Severe, Hemophilia B
- Trial name
- NCT05889754
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hasan Kalyoncu University
Rheumatologic Disease
Proof-of-concept Study of 'JIA Toolbox' for Children and Young People (CYP) With Juvenile Idiopathic Arthritis (JIA)
This project aims to further develop and conduct a 'real-world' proof-of-concept assessment of a suite of three products, known as the 'JIA Toolbox', that collectively aim to improve CYP's independence and functional ability 'JIA…
- Trial name
- JIA Toolbox (NCT05563194)
- Testing
- Heating prototype (Prototype 1), Physio tool (Prototype 2), Communication tool (Prototype 3)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Lower Extremity Fracture
Feasibility and Efficacy of the Use of Telephysiotherapy in Anantapur
Injuries remain the most frequent cause of mortality in children and young people. Studies with: telephysiotherapy programmes have published results of effectiveness, validity, non-inferiority and important advantages, providing…
- Trial name
- Telefisio (NCT04946695)
- Testing
- Telefisio India
- Volunteers
- 30 people
- Sponsor
- University of Malaga
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Languages
Establishing the Language Network With Independent Component Analysis of Resting State MRI
Proceed to an analysis of sensitivity and specificity results of the fMRI language network obtained in two ways: by providing a conventional language test and independent component analysis.
- Trial name
- ICA Langage (NCT02577757)
- Testing
- MRI
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Down Syndrome
Neurodevelopmental Treatment for Balance and Mobility in Children With Down Syndrome
The goal of this clinical trial is to evaluate whether Neurodevelopmental Treatment (NDT) can improve balance, mobility, walking capacity, and functional independence in preschool children with Down syndrome.
- Trial name
- NCT07653399
- Testing
- Neurodevelopmental Treatment (NDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Nisantasi University
Hemiplegic Cerebral Palsy
The Effect of Virtual Reality Application on Independence and Hand Functions in Daily Life in Children With CP
The aim of this study is to evaluate the effect of virtual reality applications on the level of independence and upper extremity functionality perceived by children in daily life in children with hemipegic cerebral palsy.
- Trial name
- NCT06317935
- Testing
- ArmeoSenso, Traditional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hacettepe University
Cerebral Palsy Children
Rehabilitation Assessment of Motor Function In Cerebral Palsy Using Explainable AI
The goal of this observational study is to develop and validate an AI-based prediction model for functional mobility and gait outcomes in children with cerebral palsy using low-cost clinical and gait data collected in…
- Trial name
- NCT07629024
- Testing
- AI-Based Functional Mobility and Gait Assessment
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Implementing Group Physical Therapy (PT) for Veterans With Knee Osteoarthritis (Group PT): Function QUERI 2.0
Implementing Group Physical Therapy (PT) for Veterans with Knee Osteoarthritis (OA): Function QUERI 2.0 (Group PT) aims to implement, evaluate and sustain Group PT in 16 VA sites using a type III effectiveness-implementation…
- Trial name
- Group PT (NCT05282927)
- Testing
- Implementation Strategy: Foundational REP, Implementation Strategy: Enhanced REP (enREP)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Burns
Reliability and Feasibility of WeeFIM Instrument to Measure Functional Independence in Pediatric Burns
PURPOSE: Is to test the feasibility and the reliability of the Arabic version of wee functional independence measure (weeFIM) in children with healed burns.
- Trial name
- NCT05276869
- Testing
- WeeFIM instrument
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Cairo University
Mucopolysaccharidosis
The Effect of Enzyme Replacement Therapy in Mucopolysaccharidosis
Mucopolysaccharidosis (MPS) causes chronic, progressive systemic disorders due to enzyme deficiency. Musculoskeletal manifestations of MPS include bone and vertebral deformities, restricted joint function and ROM (range of…
- Trial name
- NCT05006222
- Testing
- Enzyme Replacement Agent
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Hasan Kalyoncu University