Clinical trials: Functional Knee Pain
Knee Arthritis
Perioperative Analgesia for Knee Arthroplasty (PAKA)
Peri-articular knee infiltration with Levobupivicaine 150mg, Morphine 10mg and Ketorolac 30mg reduces postoperative pain following primary total knee replacement compared with the current standard treatment of femoral nerve…
- Trial name
- PAKA (NCT01560767)
- Testing
- Femoral Nerve Block, peri-articular infiltration
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- University of Warwick
Pediatric Obesity, Lower Extremity Biomechanics
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Childhood obesity is one of the most critical and accelerating health challenges throughout the world. It is a major risk factor for developing varus/valgus misalignments of the knee joint.
- Trial name
- NCT02545764
- Testing
- Strength and neuromuscular exercise programme
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- St. Pölten University of Applied Sciences
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Outcome After Total Knee Arthroplasty
The Association Between Pre-operative Pain Psychology and Hypersensitivity With Poor Functional Outcome After Knee Replacement.
To explore whether there are factors that help us to understand why some patient outcomes are not successful and identify prediction factors for progression.
- Trial name
- NCT03132064
- Testing
- total knee arthroplasty
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Salford
Patellofemoral Pain Syndrome, Anterior Knee Pain
Elite Athletes: Trunk Mobility, Lower Extremity Flexibility, and Functional Balance Across Sports
This cross-sectional observational study investigated the relationships among dynamic Q angle, core muscle endurance, hip flexibility, and lower extremity functional status in elite adolescent athletes with and without…
- Trial name
- NCT07326046
- Where
- Cyprus
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Knee Osteoarthritis
Comapre Effects Of Proprioceptive Training And Core Instability Strength Training In Knee Osteoarthritis Patients
This study aims to determine the influence of core instability exercises in comparison to proprioceptive training in relieving pain, improving balance and physical function in general population of knee Osteoarthritis.
- Trial name
- NCT05258227
- Testing
- Conservational Physical Therapy and Proprioceptive Strength Training, Conservational Physical Therapy and Core Instability Strength Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Patellofemoral Pain Syndrome, Chondromalacia Patellae
Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain
The purpose of this study is to determine if interventions applied at a distant site, lumbopelvic region (manipulation and TENS), have a similar effect as interventions applied locally at the knee (TENS) on quadriceps force…
- Conditions
- Patellofemoral Pain Syndrome, Chondromalacia Patellae, Anterior Knee Pain Syndrome
- Trial name
- NCT01434966
- Testing
- Lumbopelvic Manipulation, TENS- Spine, TENS- Knee
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Creighton University
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome
This observational, cross-sectional study aimed to compare dynamic Q-angle, trunk/core endurance, and lower-extremity flexibility between elite adolescent female and male sprinters with and without patellofemoral pain syndrome…
- Trial name
- PFPS-QCORE (NCT07328750)
- Testing
- Patellofemoral Pain Syndrome Status
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Knee Pain
Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
Primary Total Knee joint replacement surgery is highly successful surgery for relieving pain and improving function in patients with disabling arthritis.
- Trial name
- NCT00403273
- Testing
- Botulinum toxin A, Normal Saline
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Postoperative Pain
Effect of Volume of Local Anesthetic for Adductor Canal Block on Quadriceps Muscle Function: A Dose Finding Study
Adductor canal block is commonly offered to provide pain relief following knee surgery with the hope that they cause less leg weakness than traditionally performed femoral nerve block.
- Trial name
- NCT02541552
- Testing
- Ropivacaine 0.5%
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Patellofemoral Pain Syndrome
Comparative Effects of Perturbation and Functional Stabilization Training on Patellofemoral Pain Syndrome
The main objective of this study is to determine the comparative effects of perturbation and functional stabilization training on pain, balance, and performance in athletes with patellofemoral pain syndrome(PFPS).
- Trial name
- NCT06511362
- Testing
- Functional stabilization training, perturbation exercises
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Patello Femoral Pain Syndrome
Active Release and Myofascial Release Technique in Patients With Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is often associated with imbalance and weakness in several key muscle group. These include the quadriceps (especially the vastus medialis oblique), hip abductors and external rotators and…
- Trial name
- NCT07854041
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Abnormalities, Imaging
MRI Study of Musculoskeletal Function
This study will use magnetic resonance imaging (MRI) and ultrasound images to study how muscles, tendons, and bones work together to cause motion.
- Conditions
- Abnormalities, Imaging, Patellofemoral Pain Syndrome
- Trial name
- NCT00051857
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Anterior Cruciate Ligament Reconstruction
Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery
The purpose of this study is to see if use of RNS60 during ACL reconstruction surgery decreases pain and improves functional capacity post-operation.
- Trial name
- NCT01922427
- Testing
- RNS60
- Sponsor
- Revalesio Corporation
Painful Osteoarthritis of the Knee
Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.
Pharmacological treatment of pain due to osteoarthritis of the knee often proves to be inadequate and/or cause intolerable side effects.
- Trial name
- NCT02688543
- Testing
- RF treatment, radiofrequency ablation, ultrasound
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital General de Jerez de la Frontera
Haemophilic Arthropathy of Knee
Plyometric-Based Hydro-Kinesio Therapy in Children With Hemophilic Arthropathy
This study was designed to assess the effect of an 8-week plyometric-based hydro-kinesio therapy (Plyo-HKT) on pain, muscle strength, postural control, and functional performance in a convenience sample of children with…
- Trial name
- NCT05947110
- Testing
- Plyometric-based hydro-kinesio therapy, Standard exercise therapy
- Where
- Saudi Arabia
- Volunteers
- 48 people
- Sponsor
- Cairo University
Pain Management, Function
Evaluation of Post Hospital Administration of Celecoxib Following Minimally Invasive Knee Replacement Surgery
This study will evaluate the benefits of continuing celecoxib through six weeks of total knee arthroplasty recovery. This is a randomized, double blind study with a group of approximately 130 primary total knee patients.
- Conditions
- Pain Management, Function, Minimally Invasive Total Knee Arthroplasty, Celecoxib
- Trial name
- NCT00474773
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- St. Louis Joint Replacement Institute
Pain in Leg, Unspecified, Knee Sprain
Efficacy of Instrumental Chiropractic Treatment Using Activator Methods for Pain and Dysfunction in Juvenile Athletes
The goal of the study is to prove efficacy of instrumental chiropractic treatment for leg pain in juvenile athletes. A randomized placebo controlled clinical trial including juvenile athletes with functional impairment and pain…
- Trial name
- NCT01449994
- Testing
- Activator IV (Activator Methods Int. Phoenix, Arizona)
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Arthroplasty, Overweight and Obesity
Healthy Living After Knee Replacement
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to…
- Trial name
- NCT05190666
- Testing
- PACE Weight Loss program, Chronic Disease Self-Management
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of South Carolina