Clinical trials: Functional Neurological Disorders
Duchenne Muscular Dystrophy
Relationship Between PFTs and Pdi in DMD
A cross-sectional study to explore the relationship between clinically assessed pulmonary function test (PFT) measures and transdiaphragmatic (Pdi) measures in Duchenne muscular dystrophy (DMD) as well as to explore the…
- Trial name
- NCT03335384
- Testing
- Esophageal Balloon, Gastric Balloon, Nasal Pressure Transducer
- Sponsor
- University of Minnesota
Cerebral Palsy, Rehabilitation
The Effect of Tactile Deficit on Motor Function in Unilateral Cerebral Palsy
Cerebral palsy(CP) is the most common cause of disability in childhood. The motor spectrum of disorders is characterized by abnormal muscle tone, posture, and movement.
- Conditions
- Cerebral Palsy, Rehabilitation, Tactile Perception
- Trial name
- NCT05013814
- Testing
- Semmes-Weinstein monofilament test, Box and Block Test, 9-Hole Peg Test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Epilepsy
RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy
Resting-state functional MRI (r-fMRI) has emerged in recent years to analyze resting networks. It allows, without active participation of the patients, to identify and analyze the different functional brain networks.
- Trial name
- RESPIRE (NCT04451278)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Unilateral Cerebral Palsy
Multi Sensory Stimulation And Priming (MuSSAP) in Infants at Risk of Unilateral Cerebral Palsy
A pilot randomized clinical trial exploring the effect of a Multi Sensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants at risk of developing unilateral Cerebral Palsy.
- Trial name
- MuSSAP (NCT05533476)
- Testing
- Multi Sensory Stimulation and Priming, Intensive Usual Care (Upper Limb)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Sarcopenia
Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women
This study evaluated the effect of protein intake immediately after resistance exercise on lean mass, strength, and functional capacity gains in postmenopausal women.
- Trial name
- NCT03372876
- Testing
- Protein and carbohydrate supplementation
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Secondary Dystonia
Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia
The disability inflected by dystonia encouraged the development of many neurosurgical procedures. This is a prospective study included 120 patients suffering from intractable secondary dystonia.
- Trial name
- NCT03347240
- Testing
- Brain Lesioning, Combined anterior and posterior lumbosacral rhizotomy, Deep brain stimulation
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Cerebral Palsy (CP)
Neuromuscular Electrical Stimulation and Leap Motion-Based Exercises in Cerebral Palsy
Cerebral palsy (CP) is a group of disorders resulting from a permanent but non-progressive lesion in the developing brain, which affects the development of movement and posture and may lead to activity limitations.
- Trial name
- NCT07311018
- Testing
- Leap Motion-Based Exercise Program, NMES, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Phenylketonuria
MRI Spectroscopy and Neuropsychological Functioning in Phenylketonuria
This is a study about the relationship of brain biomarkers with neuropsychological functioning in PKU. All participants will undergo MRI spectroscopy, will provide a blood specimen and will receive neuropsychological testing.
- Trial name
- NCT03097250
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cerebral Palsy Spastic Diplegia
Effect of Electrical Stimulation With Functional Task Training on Balance and Motor Abilities in Children With Diplegia
The aims of the study are to: 1. Investigate the combined effect of functional task training with electrical stimulation of bilateral hip abductor muscles on balance in children with diplegia. 2.
- Trial name
- NCT06234215
- Testing
- functional electrical stimulation, functional task training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Child, Only
Effects of Dynamic Surface Exercise Training in Children With Diplegic Cerebral Palsy
Data will be collected after the approval of synopsis a total of 14 children with diplegic cerebral palsy of age between 6 and 8 years of both genders with Gross Motor Function Classification System of level III and IV will be…
- Trial name
- NCT07244159
- Testing
- Dynamic surface exercise training, Standard physiotherapy Training
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Diplegia
Effects of Dynamic Surface Exercise Training on Trunk Control and Gross Motor Functions in Children With Diplegic Cerebral Palsy
The purpose of this study was to determine the effect of dynamic surface exercise treatment on trunk control and gross motor abilities in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05946096
- Testing
- Dynamic surface exercise training, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Ayesha Hameed
Neuromuscular Diseases
Reliability Study of a Motor Function Measure Digitalized Playful Completion Modules
Neuromuscular diseases include more than 200 rare disorders affecting muscles or the nervous system. Functional scales assessing motor function are tools allowing to measure the evolution of motor impairment of patients with a…
- Trial name
- MFM-Play (NCT05227274)
- Testing
- Items completion with or without a MFM-Play
- Where
- 10 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Spinal Cord Injuries, Neurogenic Bladder
Pediatric Locomotor Training Bladder Study
Bladder dysfunction is one of the most important factors influencing duration and quality of life in children with spinal cord injury.
- Trial name
- NCT03559036
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Apnea, Obstructive, Tonsillitis
Evaluation of the Functional Impact of Adenotonsilectomy
Spirometric assessment of respiratory function before and after adenotonsillectomy surgery
- Conditions
- Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Respiratory Function Impaired
- Trial name
- NCT05532228
- Testing
- Adenotonsillectomy
- Where
- Portugal
- Volunteers
- 78 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Traumatic Brain Injury
Functional and MRI Evaluation of the Robot-assisted and Traditional Rehabilitation Programs on the Muscle
Walk recovery is one of the goals of rehabilitation programs in patients with acquired brain injury. Recent experiences have shown the effectiveness of rehabilitation programs including traditional physiotherapy in combination…
- Trial name
- NCT04768192
- Testing
- Physical Rehabilitation without lokomat, Physical Rehabilitation with Lokomat
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy
Task Oriented Activities Based on NDT Therapy Principles
Cerebral palsy (CP) is one of the primary causes of disability effecting majority of pediatric population. Cerebral Palsy is considered a neurological disorder caused by a non-progressive brain injury or malformation that occurs…
- Trial name
- NCT05903729
- Testing
- Neurodevelopmental therapy treatment, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Spina Bifida
Effects of Progressive Resistance Exercise Training on Endurance and Functional Mobility in Children With Spina Bifida
In this research the effects of progressive resistance exercise training on endurance and functional mobility in children with spina bifida are assessed.
- Trial name
- NCT05719636
- Testing
- Conventional treatment, Progressive resistance exercise
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Cerebral Palsy, Autonomic Nerveus System
BioFeedBack Breathing Training Influence Cardiac Autonomic Nervous System in Children With Cerebral-Palsy.
The effect of breathing biofeedback training to influence the function of the cardiac autonomic nervous system at rest and in activity in children with cerebral palsy.
- Trial name
- NCT01872507
- Testing
- Biofeedback training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
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