Clinical trials: GFR
Kidney Disease
Evaluation of New Test Method to Measure Kidney Function
This study will test the accuracy of a new "Fast GFR" (glomerular filtration rate) test to evaluate kidney function. Accurate assessment of kidney function is important in many clinical situations, including detecting kidney…
- Trial name
- NCT00026715
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Congenital Urological Abnormalities
Pilot Study of Mycophenolate Mofetil in Congenital Uropathies
Congenital or hereditary structural anomalies of the genitourinary tract account for approximately half of all cases of end stage renal disease in the pediatric population.
- Trial name
- NCT00193635
- Testing
- mycophenolate mofetil
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Northwell Health
Fabry Disease, Proteinuria
Antiproteinuric Agents and Fabry Disease
Fabry disease is a rare disorder that often has kidney involvement with increased urine protein excretion. Proteinuria is recognized as an important risk factor for progression of chronic kidney disease.
- Trial name
- NCT00343577
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Type1diabetes, Type1 Diabetes Mellitus
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
Over 1.25 million Americans have Type 1 Diabetes (T1D), increasing risk for early death from cardiovascular disease (CVD). Despite advances in glycemic and blood pressure control, a child diagnosed with T1D is expected to live up…
- Conditions
- Type1diabetes, Type1 Diabetes Mellitus, Diabetic Kidney Disease, Juvenile Diabetes
- Trial name
- COFFEE (NCT03878277)
- Testing
- Starbucks® Cold brew - 325ml bottle
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Acute Kidney Injury, Critically Ill Children
Iohexol for Measuring Renal Function
Approximately 25-35% of all children admitted to the paediatric intensive care unit (PICU) or neonatal intensive care unit (NICU) will develop Acute Kidney Injury (AKI) during the first seven days after admission.
- Trial name
- HERO (NCT03946345)
- Testing
- Iohexol Inj 300 MG/ML
- Where
- Netherlands
- Volunteers
- 105 people
- Sponsor
- Radboud University Medical Center
Fabry Disease
Fabry: Renal Function During Long-term ERT by 51Cr-EDTA Clearance
The aim of this study was to investigate renal function decline by measured glomerular filtration rate (mGFR) in patients with FD during enzyme replacement therapy, and to explore the influence of age on renal function in FD.
- Trial name
- NCT02969200
- Testing
- Enzyme replacement therapy
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Ulla Feldt-Rasmussen
Febrile Neutropenia
Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance
This clinical trial focuses on children with cancer who face infections after receiving chemotherapy. Chemotherapy affects the bone marrow, leading to a decrease in the production of certain white blood cells, particularly those…
- Trial name
- DAR-ARC (NCT06293677)
- Testing
- Dosage Adjustment Rules for Augmented Renal Clearance (DAR-ARC) for piperacillin-tazobactam and meropenem, Standard dosages of piperacillin-tazobactam or meropenem
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Chronic Kidney Disease, Renal Insufficiency
Comparison of Markers of Kidney Function
Glomerular filtration rate (GFR) is the best known measurement of kidney function. Serum creatinine (blood test) is the most commonly used marker to predict GFR.
- Trial name
- NCT01403766
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Kidney Disease, Proteinuria
Determination of Kidney Function
Much more about kidney disorders can be learned by determining kidney function. This research proposes to study the kidneys function by several parameters known as glomerular filtration rate (GFR), Renal Plasma Flow (RPF), and…
- Conditions
- Kidney Disease, Proteinuria, Autoimmune / Connective Tissue Diseases
- Trial name
- NCT00001978
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Breast Cancer
Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast Cancer
The goal of this clinical research study is to learn if Tarceva® (erlotinib hydrochloride) can help control triple receptor-negative breast cancer. The safety of this drug will also be studied.
- Trial name
- NCT00739063
- Testing
- Tarceva
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Renal Function Disorder
Development and Validation of Creatinine-Based Estimates of the Glomerular Filtration Rate Equation
This study aim to recruit all Electronic Medical Record of patients who underwent for 51chromium ethylenediamine tetra acetic acid (51Cr-EDTA) imaging at the Nuclear Medicine Centre, University Malaya Medical Centre from…
- Trial name
- NCT05112393
- Testing
- Development of new estimating Glomerular Filtration Rate (eGFR) equation, Validation of new estimating Glomerular Filtration Rate (eGFR) equation
- Where
- Malaysia
- Volunteers
- 200 people
- Sponsor
- University of Malaya
Chronic Kidney Disease, End-Stage Renal Disease
Establish the Caring Model of Children With Chronic Kidney Disease and End-stage Renal Disease: To Set up Childhood Glomerular Filtration Rate (GFR) Formula in Taiwan
Inulin's usefulness as a diagnostic agent is based on the method of its elimination from the body. Inulin is biologically inert, unbound by plasma proteins, freely filtered at the glomerulus, and is neither reabsorbed…
- Trial name
- NCT01250626
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Chronic Kidney Disease
The Valid of GFR in Chronic Kidney Disease Patients
Study was cancel due to principle investigator had been resigned
- Trial name
- NCT04610996
- Volunteers
- healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Renal Function Disorder
Renal Function Measurements in Children
The purpose of this study is to validate a feasible, safe and reliable iohexol plasma clearance method in routine monitoring of the renal function (GFR) in children.
- Trial name
- NCT01092260
- Where
- Norway
- Volunteers
- 96 people
- Sponsor
- Haukeland University Hospital
Congenital Solitary Kidney
Long Term Outcome of Congenital Solitary Kidney
Congenital solitary kidney (CSK) is a disorder caused by an abnormal development of one of the two kidneys. The reported incidence ranges between 1:450-3200. It is debated whether CSK is a benign condition or not.
- Trial name
- CSKP (NCT01831141)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Iohexol, Pharmacokinetics
Renal Function Assessment in Critically Ill Children
Identification of renal dysfunction in critically ill children is often delayed due to lack of accurate methods for evaluation of glomerular filtration rate (GFR).
- Conditions
- Iohexol, Pharmacokinetics, Renal Function, Critically Ill Children
- Trial name
- IOHEXOL (NCT05179564)
- Testing
- iohexol administration, iohexol blood sampling
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Classic Bladder Exstrophy, Renal Function
Kidney Function in Patients With Bladder Exstrophy
Patients with classical bladder exstrophy undergo many surgical interventions with secondary urinary tract infections complicating their course.
- Conditions
- Classic Bladder Exstrophy, Renal Function, GFR, Proteinuria
- Trial name
- NCT02192801
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Kidney Donation, Kidney Failure
Live Kidney Donor Study -Renal Function Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Conditions
- Kidney Donation, Kidney Failure, Kidney Transplantation
- Trial name
- NCT01158742
- Testing
- Glomerular Filtration Rate with Iothalamate, Glomerular Filtration Rate with Iohexol
- Where
- 3 sites in United States
- Volunteers
- 402 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Kidney Disease
Assessment of Serum Cystatin C as a Marker of Kidney Function in Children
The purpose of this study is to assess serum cystatin C as a marker of kidney function (glomerular filtration rate, GFR) in children aged 2-14.
- Trial name
- NCT00300066
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Renal Disease, Renal Insufficiency
Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance
The purpose of this study is to measure glomerular filtration rate (GFR) by iohexol plasma disappearance (gold standard) and measure serum Cystatin C levels (surrogate marker) in patients enrolled in our prospective study at…
- Trial name
- NCT01545531
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Washington