Clinical trials: GI Cancer
Biliary Disease, Pancreatitis
Los Angeles Prospective GI Biliary and EUS Series
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound are increasingly being used to manage complex disease of the bile duct, pancreas and cancer.
- Conditions
- Biliary Disease, Pancreatitis, Gastrointestinal Neoplasms
- Trial name
- NCT02196935
- Testing
- clinical course
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- University of Southern California
Primary Malignant Neoplasm of Lung, Primary Malignant Neoplasm of Gastrointestinal Tract
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Consecutive Cohort Study
To assess the feasibility of a creative writing intervention in an advanced cancer population. Given it is a relatively simple intervention delivered by a non-clinician, the investigators are interested in better understanding…
- Trial name
- NCT02575898
- Testing
- First Session, Second Session, Third through Sixth Sessions
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Circulating Tumor Cell, Gastrointestinal Cancer
EUS Guided HVA and PVA for Circulating Tumor DNA in Patients
The discovery of cell-free circulating tumor DNA (crDNA) in blood and the maturation of technologies for ctDNA analysis have presented an attractive opportunity for minimally invasive "liquid biopsy" genomic diagnostics.
- Trial name
- NCT04782557
- Testing
- EUS-guided portal vein and hepatic vein aspiration
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Digestive System Neoplasms, Surgery
Observatory of the Quality of Surgical Procedures for Digestive Cancers
Surgery for digestive cancers is managed according to quality standards, validated by the scientific community. Despite the diffusion of these standards through the benchmarks of good practice, the results of the surgery remain…
- Conditions
- Digestive System Neoplasms, Surgery, Surgery--Complications, Quality of Health Care
- Trial name
- Obchir (NCT03681600)
- Where
- 4 sites in Morocco
- Volunteers
- 1,043 people
- Sponsor
- Moroccan Society of Surgery
Blood Cancer
Development of a Multi-biomarker Panel for Prognostic Stratification and Treatment Response Prediction in Acute Graft Versus Host Disease of the Gut
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a life-saving treatment for many malignant hematologic diseases.
- Trial name
- GUT-PREDICTION (NCT07305090)
- Testing
- Adult and pediatric patients with hematological diseases treated with allogeneic hematopoietic cell transplantation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Irritable Bowel Syndrome, Colitis, Ulcerative
Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders
This clinical trial hypothesize that Gut Microbiota (bacteria, viruses, fungi)play a major role in the occurrence and progression of many chronic gastrointestinal diseases like Irritable Bowel Syndrome, Inflammatory Bowel…
- Conditions
- Irritable Bowel Syndrome, Colitis, Ulcerative, Crohn Disease, Colonic Neoplasms
- Trial name
- NCT01099111
- Where
- Saudi Arabia
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Digestive Cancer
Factors Influencing Inclusion in Digestive Cancer Clinical Trials
Since the early 1990s, evidence-based medicine has played an increasingly important role in decision-making for the treatment of patients with cancer.
- Trial name
- INDICT (NCT02894775)
- Where
- France
- Volunteers
- 408 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Childhood Soft Tissue Sarcoma, Childhood Liver Cancer
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of liposomal doxorubicin in treating children who have…
- Conditions
- Childhood Soft Tissue Sarcoma, Childhood Liver Cancer, Bone Cancer, Brain Tumor
- Trial name
- NCT00019630
- Testing
- doxorubicin HCl liposome
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Gastrointestinal Tract Cancer
Serum Carotenoids and Risk of Gastrointestinal Tract Cancer: Meta-analysis of Ten Studies
Previous studies have suggested that serum carotenoids may be associated with risk of gastrointestinal tract cancer (GIT cancer), but the results were inconsistent.
- Trial name
- NCT03433092
- Testing
- serum carotenoids
- Where
- China
- Volunteers
- 40,641 people
- Sponsor
- Yong Zhou
Cholangiocarcinoma, Gallbladder Cancer
Avastin and Tarceva for Upper Gastrointestinal Cancers
Erlotinib and bevacizumab have shown activity individually, as single drugs, or in combination with chemotherapy in upper gastro-intestinal cancers, including esophageal and gastro-esophageal adenocarcinomas, gastric cancer and…
- Trial name
- NCT00350753
- Testing
- Erlotinib and bevacizumab
- Where
- 3 sites in Denmark
- Volunteers
- 126 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colorectal Neoplasms
Artificial Intelligence for Diminutive Polyp Characterization
Artificial intelligence is a promising tool that may have a role in characterizing colon epithelial lesions (CADx), helping to get a reliable optical diagnosis regardless of the endoscopist experience.
- Trial name
- NCT05391477
- Testing
- GI-Genius artificial intelligence
- Where
- Spain
- Volunteers
- 643 people
- Sponsor
- Hospital Universitario La Fe
Gastrointestinal Cancer
68Ga-PMD22 PET/CT Examination Targeting CLDN18.2
To investigate the ability of the CLDN18.2-targeted 68Ga-PMD22 tracer to detect CLDN18.2 expression in patients with gastric and colorectal cancer and other gastrointestinal tumours.
- Trial name
- NCT05937919
- Testing
- Intravenous injection of 68Ga-PMD22
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking Union Medical College Hospital
Benign Neoplasm, Pathology
Deep Biopsy Via Endoscopic Submucosal Dissection in Upper GI Subepithelial Tumors
Upper gastrointestinal subepithelial tumors are frequently encountered during esophagogastroduodenoscopy. Treatment plans for subepithelial tumors are determined by algorithms based on endoscopic ultrasonography images.
- Trial name
- NCT01993199
- Testing
- deep biopsy via ESD technique
- Volunteers
- 40 people
- Sponsor
- Hanyang University Seoul Hospital
Cancer
Immunotherapy Treating GI Cancer
The primary objectives are to evaluate the safety and efficacy of infusion of autologous gastro-intestinal (GI) cancer antigen-specific engineered immune effector cells (EIE).
- Trial name
- NCT03614650
- Testing
- engineered immune cells
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
GI Cancer, Thoracic Cancer
Comparison of a Web-based Advance Directive to a Standard Advance Directive
This study will compare a web-based advance directive to a standard advance directive.
- Trial name
- NCT03676426
- Testing
- Web platform for advance care planning/advance directive, Standard advance directive
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Pennsylvania
Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors (GIST) Registry
The goal of this observational research study is to establish a registry of information regarding how different physicians treat and manage patients with gastrointestinal stromal tumors (GISTs). Objectives: 1.
- Trial name
- NCT00507273
- Testing
- GIST Registry
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Colorectal Cancer, Recurrent Colorectal Cancer
Phase I/II Trial of Antagonism of HER in GI Cancer
Recruitment to phase I of the PANTHER trial is complete. Phase II, is to evaluate the best overall response rate for AZD8931 + FOLFIRI treatment.
- Trial name
- PANTHER (NCT01862003)
- Testing
- AZD8931, Irinotecan, Folinic Acid
- Where
- 4 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
GI Cancer
Prevalence of Types and Patterns of Gastrointestinal Polyps in Assiut University Hospitals ( Cross Sectional Study
Gastrointestinal polyps (GIPs) are unusual growths of epithelial tissue projecting from the mucosa of gastrointestinal tract (GIT) and one of the most common pathologies affecting GIT .
- Trial name
- Polyp (NCT06929117)
- Volunteers
- 130 people
- Sponsor
- Assiut University
Small Intestine Disease, Small Intestine Cancer
Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)
Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- SODA (NCT03771508)
- Where
- 30 sites in United States
- Volunteers
- 3,712 people
- Sponsor
- Medtronic - MITG
Digestive System Malignancies
An Exploratory Study on Microbial Biomarkers Associated With the Efficacy of Neoadjuvant Therapy
Digestive system malignancies are among the most common types of cancers in China, primarily including esophageal cancer, gastric cancer, pancreatic cancer, liver cancer, and colorectal cancer.
- Trial name
- NCT07263620
- Testing
- This study is observational and involves no interventions.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital