Clinical trials: GI Disorders
Small Intestine Disease, Small Intestine Cancer
Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)
Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- SODA (NCT03771508)
- Where
- 30 sites in United States
- Volunteers
- 3,712 people
- Sponsor
- Medtronic - MITG
Superior Mesenteric Artery Syndrome
SMAS: a Prospective Study in a Single Institution
Superior Mesenteric Artery Syndrome (SMAS) is a rare cause of duodenal obstruction, that should be suspected in cases of chronic, refractory upper digestive symptoms.
- Trial name
- NCT03416647
- Testing
- Duodenojejunostomy
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- Azienda Ospedaliera di Padova
Appendicitis
Non-operative Management of Early Appendicitis in Children
The purpose of this study is to determine the feasibility of non-operative management of early appendicitis in children. We hypothesize that non-operative management of early appendicitis in children with antibiotics alone will…
- Trial name
- NCT01718275
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Peter Minneci
Irritable Bowel Syndrome, Disorders of Gut-brain Interaction
Audio-recorded Gut-Hypnotherapy for Sleep and Pain in Pediatric Abdominal Pain Disorders
Children with irritable bowel syndrome (IBS) and functional abdominal pain- not otherwise specified (FAP-NOS) have higher rates of poor sleep quality.
- Trial name
- NCT07216092
- Testing
- Gut-directed Hypnotherapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Children's Hospital at Montefiore
Colorectal Cancer
RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma
RAD001 (everolimus) is a novel oral derivative of rapamycin. RAD001 has been in clinical development since 1996 as an immunosuppressant in solid organ transplantation and has obtained marketing authorization (Certican®) for…
- Trial name
- NCT01047293
- Testing
- RAD001, FOLFOX, Bevacizumab
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Rumination Syndrome
Baclofen for Children With Rumination Syndrome
The goal of this clinical trial is to learn about baclofen in pediatric patients with rumination syndrome. The main question it aims to answer is whether baclofen is effective in treating children with rumination syndrome.
- Trial name
- NCT05975684
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Helicobacter Pylori Infection, Peptic Ulcer
Treatment Efficacy of Regimens With and Without Bismuth in Children With Helicobacter Pylori-Associated Peptic Ulcer Disease
The goal of this clinical trial is to learn if including bismuth in the treatment helps heal stomach and duodenal ulcers caused by Helicobacter pylori (H. pylori) in children.
- Trial name
- NCT07260006
- Testing
- Bismuth quadruple therapy, Triple therapy with PPI + Amoxicillin + Metronidazole
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Deglutition Disorders, Dysphagia
Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia
This research aims to facilitate the successful implementation of the new Heart and Stroke Foundation of Ontario dysphagia screening model for acute stroke patients.
- Conditions
- Deglutition Disorders, Dysphagia, Stroke
- Trial name
- NCT00570557
- Testing
- TOR-BSST© Refresher Training
- Where
- 5 sites in United States, Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Gastroenteritis, Vomiting
Oral Disintegrating Ondansetron Tablet to Reduce Vomiting From Gastroenteritis in a Pediatric Emergency Department
The objectives of the study were to determine whether ondansetron treatment would reduce: the amount of vomiting in the emergency department; the need for intravenous rehydration; and the need for hospitalization.
- Conditions
- Gastroenteritis, Vomiting, Diarrhea, Dehydration
- Trial name
- NCT00120744
- Testing
- Ondansetron Oral Disintegrating Tablet
- Sponsor
- The Hospital for Sick Children
Celiac Disease
Gut Permeability Assessment in Celiac and Gluten Sensitive Children
This study will assess the effect of gluten on gut barrier function. Investigators at the Mayo Clinic have developed a new gut permeability test using rhamnose (sugar \& water solution), and are hoping to prove its effectiveness…
- Trial name
- NCT02690532
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Ulcerative Colitis
Study for the Treatment of Ulcerative Colitis With Adacolumn (Companion to US Study 512-04-205)
The purpose of the study is to demonstrate the safety and effectiveness of the Adacolumn Apheresis System to treat the signs and symptoms of ulcerative colitis.
- Trial name
- NCT00219414
- Testing
- Adacolumn Apheresis System
- Volunteers
- 42 people
- Sponsor
- Otsuka Frankfurt Research Institute GmbH
Gastrointestinal Stromal Tumors
A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore
To review the characteristics and treatment of gastrointestinal tumours at the two tertiary centres in Singapore
- Trial name
- NCT00718211
- Where
- Singapore
- Sponsor
- National University Hospital, Singapore
Colonic Neoplasms
Establishing Effective Screening Methods for Diagnosing Hereditary Nonpolypoisis Colorectal Cancer
Correct identification of Lynch syndrome at the time of colorectal cancer presentation is important. We aim to find best ways to screen patients with colorectal cancer in Korea.
- Trial name
- NCT00516230
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Necrotizing Enterocolitis
Intestinal Failure in Necrotising Enterocolitis
Necrotizing enterocolitis (NEC) is a severe gastrointestinal disorder with high morbidity and mortality (20-40%), affecting predominantly premature neonates. NEC continues to present a diagnostic challenge to clinicians.
- Trial name
- NCT01441739
- Where
- 2 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Inflammatory Bowel Diseases
JUMP Inflammatory Bowel Disease Study
Children and adolescents with inflammatory bowel disease are at increased risk of poor bone and muscle health through a variety of factors, including underlying disease processes, nutritional deficits, and reduced physical…
- Trial name
- JUMP IBD (NCT04067934)
- Testing
- Jumping Exercise programme
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- NHS Greater Glasgow and Clyde
Appendicitis
Perioperative Pain Management of Pediatric Appendectomy Patients
Acute appendicitis is the most common illness that brings pediatric patients to the hospital for surgical treatment. Abdominal pain is the symptom because of which the patients go to the hospital.
- Trial name
- umpikipu (NCT02580487)
- Testing
- appendicectomy
- Where
- Finland
- Volunteers
- 178 people
- Sponsor
- Kuopio University Hospital
Growth, Tolerance
Human Milk Oligosaccharides (HMOs) Post-market Study on Infants
Human milk oligosaccharides (HMOs) represent the third largest solid component of breast milk. Technology advancements made it possible to supplement infant formulas with HMOs (2'FL, LNnT).
- Conditions
- Growth, Tolerance, Adverse Event, Disorder of Intestine
- Trial name
- NEHMO (NCT04055363)
- Testing
- HMO-supplemented infant formula
- Where
- 6 sites in Spain
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Eosinophilic Esophagitis
CEGIR 7807: Validation of Online Cohort of EGID Patients Enrolled in RDCRN CEGIR Contact Registry
The purpose of this study is to validate the online cohort of EGID patients enrolled in the RDCRN CEGIR CR. In order to achieve this objective, the investigators will determine the agreement between self-reported EGID information…
- Trial name
- NCT03382678
- Where
- 2 sites in United States
- Volunteers
- 187 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gastroenteritis
A Study to Evaluate the Safety and Efficacy of Domperidone in Pediatric Participants With Nausea and Vomiting Due to Acute Gastroenteritis
The purpose of this study is to demonstrate that domperidone suspension plus oral rehydration therapy (ORT) is more effective than placebo plus ORT at reducing the symptoms of vomiting associated with acute gastroenteritis (AG)…
- Trial name
- NCT02699385
- Testing
- Oral Rehydration Therapy, Domperidone
- Where
- 29 sites in Austria, Belgium and 4 more
- Volunteers
- 10 people
- Sponsor
- Janssen-Cilag International NV
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