Clinical trials: Gabapentin
Anxiety Disorder, Mood Disorder
New Drugs in the Treatment of Mood Disorders
This clinical study compares the effectiveness of two anticonvulsants Lamotrigine (Lamictal) Monotherapy and Gabapentin (Neurontin) in patients with treatment resistant affective disorders.
- Conditions
- Anxiety Disorder, Mood Disorder, Psychotic Disorder
- Trial name
- NCT00001482
- Testing
- Lamotrigine (Lamictal® (Registered Trademark), Gabapentin (Neurontin® (Registered Trademark))
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Liver Cirrhosis
Gabapentin in Treatment of Muscle Cramps in Patients With Liver Cirrhosis
Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. Quinine was suggested for treatment of patients with muscle cramps in patients with liver cirrhosis.
- Trial name
- NCT02642484
- Testing
- Gabapentin, Calcium Carbonate
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Chronic Pain
Study to Compare Gabapentin to Tramadol in Children With Chronic Neuropathic or Mixed Pain
This study evaluates the efficacy and safety of gabapentin relative to tramadol for the treatment of chronic, neuropathic or mixed pain in the paediatric population.
- Trial name
- GABA-1 (NCT02722603)
- Testing
- gabapentin, tramadol
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 2 people
- Sponsor
- Pharmaceutical Research Management srl
Pain
Comparing Gabapentin and Amitriptyline for the Treatment of Neuropathic Pain in Children and Adolescents
The objective of the study is to compare the efficacy of gabapentin and amitriptyline for treating neuropathic pain in children in a randomized controlled trial.
- Trial name
- NCT00312260
- Testing
- Gabapentin, Amitriptyline
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- The Hospital for Sick Children
Bariatric Surgery Analgesia
The Effect of Preoperative Gabapentin on Postoperative Pain Control and Analgesic Requirements Following Bariatric Surgery
The importance of bariatric anesthesia and analgesia research cannot be ignored as it can inform and improve the perioperative protocols for other patients with morbid obesity irrespective of the surgical procedures they are…
- Trial name
- NCT07169006
- Testing
- Group 1, Group 2
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Autism Spectrum Disorder
Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of Gabapentin
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is increasing in prevalence, and is characterized by deficits in social communication and interaction across multiple contexts, and restricted, repetitive…
- Trial name
- NCT03589898
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Massachusetts, Worcester
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Bronchial Asthma
Study of Efficacy of Gabapentin in Therapy of Bronchial Asthma
The purpose of this study is to determine whether antiepileptic drug gabapentin is effective in the treatment of chronic asthma.
- Trial name
- NCT00153283
- Testing
- Gabapentin
- Volunteers
- 68 people
- Sponsor
- Centre of Chinese Medicine, Georgia
Neurologically Impaired, Irritable Mood
Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Children
This study is a prospective, randomized, double blind, placebo controlled, crossover clinical trial looking at whether gabapentin can provide symptom relief for chronic irritability in neurologically impaired children.
- Conditions
- Neurologically Impaired, Irritable Mood, Signs and Symptoms, Digestive, Sleeplessness
- Trial name
- NCT01675960
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gillette Children's Specialty Healthcare
Scoliosis, Pain
Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients
Acute pain management following major surgical procedures in pediatric patients continues to be a challenge, especially after extensive posterior spine fusions.
- Trial name
- NCT02558010
- Testing
- Methadone, Normal Saline, Morphine
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medical College of Wisconsin
Anterior Cruciate Ligament (ACL) Reconstruction
Gabapentin Premedication for ACL Reconstruction: RCT
This double blind randomized control trial will enroll 100 participants ages 12-18 years, undergoing ACL repair. Participants receive gabapentin or placebo preoperatively.
- Trial name
- NCT03417479
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Epilepsies, Partial
A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
Examine the efficacy, safety and pharmacokinetics of gabapentin as adjunctive therapy in Japanese pediatric patients with partial seizures
- Trial name
- NCT00603473
- Testing
- gabapentin
- Where
- 26 sites in Japan
- Volunteers
- 92 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Tonsillitis, Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic…
- Trial name
- NCT03625011
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Refractive Errors
The Effect of Gabapentin (Neurentin) and Pregabalin (Lyrica) in Pain Reduction After Photorefractive Keratectomy
The studied patients will be given randomly one of three following drugs1:Gabapentin2: Pregabalin or placebo for 3 days after Photorefractive keratectomy surgery.
- Trial name
- PRK (NCT01122004)
- Testing
- Pregabalin
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
RLS
An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
The objectives of the trial are to evaluate the long-term efficacy and safety of HORIZANT (Gabapentin Enacarbil) 600 mg daily, for the treatment of RLS in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe…
- Trial name
- RLS (NCT02633683)
- Testing
- HORIZANT 600 mg
- Where
- 11 sites in United States
- Volunteers
- 144 people
- Sponsor
- XenoPort, Inc.
Adolescent Idiopathic Scoliosis
Effect of Spinae Erector Block (ESP) and Gabapentin on Recovery and Length of Stay in Adolescent Spinal Fusion Patients
A retrospective cohort study comparing time to ambulation (hours) between two groups of adolescent spinal fusion patients: a group who received intravenous multimodal analgesic strategy alone (MMA group) and another group who…
- Trial name
- NCT06096480
- Testing
- gabapentin + bilateral spine erector block
- Where
- Argentina
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Chest Pain, Paresthesia
Efficacy of Gabapentin in the Treatment of Chest Pain and Paresthesia in Patients With Sternotomy
In this study, the investigators aim to demonstrate the efficacy of gabapentin compared with diclofenac in the treatment of chronic non-ischemic chest pain and paresthesia of the patients with sternotomy and to elucidate the…
- Trial name
- NCT00800527
- Testing
- Gabapentin, Diclofenac
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Usak State Hospital
Emergence Agitation After Desflurane Anesthesia
Gabapentin Oral Solution in Decreasing Desflurane Associated Emergence Agitation
to study the effect of oral gabapentin (5 mg/kg) on emergence agitation after desflurane anesthesia in pediatrics undergoing starbismus surgery
- Trial name
- NCT03347916
- Testing
- Gabapentin Oral Solution [Neurontin]
- Where
- Kuwait
- Volunteers
- 75 people
- Sponsor
- Kuwait Specialized Eye Center
Pain, Postoperative
Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery.
- Trial name
- NCT04724252
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Insomnia
Gabapentin's Effects on Insomnia in Patients With Recent Concussion
In this open-label, pilot study the investigators will be assessing gabapentin's effects on insomnia and other concussion-related symptoms in patients with a recent concussion experiencing insomnia.
- Trial name
- NCT01421264
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- State University of New York at Buffalo