Clinical trials: Gastro-Intestinal Disorders
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Eosinophilic Esophagitis
Prospective Database for Eosinophilic Esophagitis (EoE) of Pediatric Population
Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated allergic inflammatory disorder that is being diagnosed with increased frequency.
- Trial name
- EoE (NCT05176249)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Eosinophilic Gastrointestinal Disorders (EGID), Eosinophilic Esophagitis
Registry for Eosinophilic Gastrointestinal Disorders (REGID)
Develop Registry tool
- Conditions
- Eosinophilic Gastrointestinal Disorders (EGID), Eosinophilic Esophagitis, Eosinophilic Disorder
- Trial name
- EoE (NCT01382563)
- Where
- 8 sites in United States
- Volunteers
- 34 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Gastroesophageal Reflux
SWAN: Study on the Tolerance and Efficacy of a New Anti-regurgitation Formula (PC-2016-01)
The aim of this study is to evaluate the efficacy of a new thickened formula on regurgitation
- Trial name
- SWAN (NCT02710955)
- Testing
- Thickened infant formula
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- United Pharmaceuticals
Esophagitis, Eosinophilic
The Potential Role of Compounds Derived From Ultra-processed Foods in Pathogenesis of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a chronic antigen-mediated inflammatory disease of the esophagus that affects both children and adults.
- Trial name
- NCT06093204
- Testing
- Dietary evaluation
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Laryngomalacia, Gastro Esophageal Reflux
Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia
Laryngomalacia (LM) is the most common cause of stridor in infants. Symptoms of gastroesophageal reflux (GER) are often seen in the setting of LM; therefore, acid suppression therapy (AST) has been empirically used in the…
- Trial name
- NCT04614974
- Testing
- Famotidine, Speech Language Therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Reema Padia
Thyroidectomy, Voice Alteration
Impact of Total Thyroidectomy on Voice and Swallowing
Purpose of this study is to evaluate the outcome of total thyroidectomy on vocal and swallowing function.
- Conditions
- Thyroidectomy, Voice Alteration, Swallowing Alteration
- Trial name
- NCT01607242
- Testing
- Endoscopy of larynx, Voice Handicap Index, Swallowing Assesment
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Intestinal Failure, Short Bowel Syndrome
Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure
This protocol outlines a randomized,open label trial examining the safety, pharmacology and efficacy of Glucagon like peptide 2 (GLP-2) in infants and children with intestinal failure.
- Trial name
- GLP-2-01 (NCT01573286)
- Testing
- Glucagon-Like Peptide 2, Glucagon like peptide-2
- Where
- 4 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Alberta Children's Hospital
Swallowing Disorder, Chewing Problem
Chewing and Swallowing Training Program in Coffin-Lowry Syndrome
This study will report the chewing and swallowing disorders of a Coffin-Lowry Syndrome (CLS) patient, and effects of chewing and swallowing training on chewing and swallowing function.
- Trial name
- NCT04199546
- Testing
- Chewing and swallowing rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Hacettepe University
Anorexia Nervosa
Gastrointestinal Interoception in Anorexia Nervosa
Anorexia nervosa (AN) has among the highest mortality rate of any psychiatric illness, yet we have a poor understanding of the biological causes of this disorder.
- Trial name
- NCT05111977
- Testing
- Vibrant capsule
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Gastroesophageal Reflux
Prevalence, Predictors and Management of Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
From January 2017 to January 2022, we looked at patients who had primary LSG and developed GERD. Before and after surgery, patients for LSG performed barium meal in Trendelenburg position and upper GIT endoscopy.
- Trial name
- LSG-GERD (NCT05416645)
- Testing
- patients with GERD after LSG
- Where
- Egypt
- Volunteers
- 1,537 people
- Sponsor
- Mansoura University
Gastric or Duodenal Ulcers
Special Drug Use Surveillance of Vonoprazan for "Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Low-dose Aspirin: Long-term Use"
The purpose of this survey is to investigate the safety and effectiveness of long-term administration of vonoprazan tablets for up to 12 months in the routine clinical setting in patients receiving low-dose aspirin.
- Trial name
- NCT03214094
- Testing
- Vonoprazan
- Where
- Japan
- Volunteers
- 1,119 people
- Sponsor
- Takeda
Cancer
Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis
RATIONALE: A step-by-step procedure may help health care practitioners diagnose and treat cancer patients with bowel injury symptoms caused by radiation therapy.
- Trial name
- NCT00737230
- Testing
- educational intervention, questionnaire administration, assessment of therapy complications
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Crohn's Disease, Vitamin D Deficiency
Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency
Aims:Prospectively observe the effects of Caltrate supplementation on the chronic course of Crohn's disease patients, analyze whether the effect of Caltrate on CD patients is affected by factors such as disease site, disease…
- Conditions
- Crohn's Disease, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04276636
- Testing
- Caltrate Pill
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
IBS - Irritable Bowel Syndrome
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling.
- Trial name
- IBS (NCT03178877)
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Eosinophilic Esophagitis (EoE)
OBS in Adolescent and Adults With EOE: A Phase II, Randomized, Double-Blind, Placebo Controlled, Study With an Open Label Extension
This is a clinical trial to test an experimental drug for the treatment of Eosinophilic Esophagitis (EoE)
- Trial name
- NCT01642212
- Testing
- Oral Budesonide Suspension (MB-9)
- Where
- 23 sites in United States
- Volunteers
- 93 people
- Sponsor
- Shire
Rumination
Do Isreali Infants of Ethiopian Origin Mother Regurgitate More Than Other Infants?
Nursing team of well baby nursery at Hillel Yaffe medical center in Hadera, Israel have noticed that infant of Ethiopian-origin mothers regurgitate more than other infants.
- Trial name
- NCT01185327
- Testing
- Breastfeeding
- Where
- Israel
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Chronic Cough (CC), Gastroesophageal Reflux (GER)
Impact of Gastroesophageal Reflux and Aspiration on Airway Inflammation and Microbiome in Children With Chronic Cough
Using an active cohort of children in whom Airway and gastrointestinal endoscopy will be performed, investigators will conduct a chart review to obtain relevant clinical data and the investigators will use an aliquot of airway…
- Trial name
- NCT02797756
- Testing
- Esophago-gastro-duodenoscopy (EGD) with biopsy, Esophageal Impedance Monitoring (EIM)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- NYU Langone Health
Water-Electrolyte Imbalance, Intensive Care Units
Fluid Overload and Pulmonary Function
Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft.
- Conditions
- Water-Electrolyte Imbalance, Intensive Care Units, Pediatric, Critical Illness
- Trial name
- NCT05129930
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Pirogov Russian National Research Medical University
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