Clinical trials: Gastro-Intestinal Disorders
Gastrointestinal Disorders
iEAT 2.0 Open Trial
The purpose of this study is to learn more about the eating behaviors of children with chronic food refusal. Specifically, investigator's aim to see how the integrated Eating Aversion Treatment (iEAT) may affect a child's food…
- Trial name
- NCT03383029
- Testing
- iEAT Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Cancer
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Indinavir and ritonavir may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00637637
- Testing
- indinavir sulfate, ritonavir, radiation therapy
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Oncology Institute of Southern Switzerland
Dysphagia
Intermittent Oro-Esophageal Tube Feeding Using Individually-Customized 3-Dimensional Printing
The aim of this study is to test the clinical effectiveness of IOE tube using individually customized 3-dimentional printed guiding tube as an alternative to Levin tube feeding when unconscious patients have no choice but tube…
- Trial name
- NCT02822456
- Testing
- VFSS
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Ulsan University Hospital
Gastroesophageal Reflux Disease (GERD)
Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patients
This study is a phase III, multi-centre, randomized, double-blind study to assess the safety and tolerability of once daily treatment with esomeprazole 20 or 40 mg in pediatric and adolescent patients 12 to 17 years of age…
- Trial name
- NCT00241501
- Testing
- Esomeprazole (Nexium)
- Where
- 40 sites in United States, Canada and 2 more
- Volunteers
- 140 people
- Sponsor
- AstraZeneca
Hypereosinophilic Syndrome, Systemic Mastocytosis
Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes
This trial is for various types of malignancies which may depend on certain enzymes (tyrosine kinases) for growth. The objective of this study is to assess to what extent imatinib mesylate blocks these enzymes and to assess the…
- Conditions
- Hypereosinophilic Syndrome, Systemic Mastocytosis, Chronic Myelomonocytic Leukemia, Dermatofibrosarcoma
- Trial name
- NCT00171912
- Testing
- imatinib mesylate
- Where
- Australia
- Volunteers
- 38 people
- Sponsor
- Novartis Pharmaceuticals
Gastric Cancer, Colorectal Cancer
Development and Utilization of an Integrated Clinical Genomic Database
This observational study aims to develop an integrated genomic and clinical database to support the discovery and validation of biomarkers for cancer diagnosis, treatment selection, and prediction of treatment response.
- Conditions
- Gastric Cancer, Colorectal Cancer, Lung Cancer (NSCLC), Liver Cancer
- Trial name
- SMC-4S (NCT07911267)
- Where
- South Korea
- Volunteers
- 118,750 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Allergy, Asthma
Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders
This study will evaluate and follow patients with various allergic, hypersensitivity and inflammatory disorders. The protocol is not designed to test new treatments; patients will be managed with standard of care therapies.
- Conditions
- Allergy, Asthma, Allergic Rhinitis, Mastocytosis
- Trial name
- NCT00557895
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Nutritional and Metabolic Diseases, Oncologic Disorders
Prognostic Performance of the Naples Prognostic Score
To investigate the prognostic performance of the Naples Prognostic Score in gastric cancer patients undergoing surgery
- Trial name
- NPS (NCT03272646)
- Testing
- surgery
- Volunteers
- 477 people
- Sponsor
- University of Campania Luigi Vanvitelli
Parkinson Disease
Effects of Osteopathic Visceral Manipulation on the Autonomic Nervous System, Balance and Gastrointestinal Disturbances in Individuals With Parkinson's Disease
Introduction: Parkinson's disease (PD) is responsible for several changes in the body, such as balance, gastrointestinal and autonomic disorders and are associated with impairments in the clinical prognosis of these individuals.
- Trial name
- NCT05047796
- Testing
- Intervention Protocol
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Instituto Docusse de Osteopatia e Terapia Manual
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study
Peppermint oil has shown to be effective in the treatment of Irritable Bowel Syndrome (IBS) symptoms in adults. Few studies of low quality are performed in an paediatric setting.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Child, Adolescent
- Trial name
- MINT (NCT05799053)
- Testing
- Small intestinal release peppermint oil, Peppermint sweets
- Where
- 3 sites in Netherlands
- Volunteers
- 228 people
- Sponsor
- St. Antonius Hospital
Chronic Granulomatous Disease
Neutrophil Oxidative Burst in Early and Late Onset Pediatric Inflammatory Bowel Disease
ABSTRACT Introduction Residual or absent oxidase function in peripheral neutrophils may point to an inborn defect of neutrophil function - chronic granulomatous disease (CGD) - whereas low to normal oxidative burst capacity has…
- Trial name
- NCT06162936
- Testing
- Phagoburst, Lymphocytes subsets, Genetic testing
- Where
- Romania
- Volunteers
- 150 people
- Sponsor
- National Institute for Mother and Child Health Alessandrescu Rusescu
Reflux Esophagitis, Gastric Ulcer
A Study of Esomeplazole (D961H) in Japanese Paediatric Patients With Reflux Esophagitis, Gastric Ulcer or Duodenal Ulcer
This is an open label, parallel group, multi-centre, phase III study to assess the safety and efficacy of D961H in maintenance therapy following initial healing therapy in Japanese paediatric patients with reflux esophagitis, and…
- Conditions
- Reflux Esophagitis, Gastric Ulcer, Duodenal Ulcer
- Trial name
- NCT03553563
- Testing
- D961H capsule 10mg, D961H sachet 10mg
- Where
- 15 sites in Japan
- Volunteers
- 50 people
- Sponsor
- AstraZeneca
Oesophageal Atresia, Dumping Syndrome
Dumping Syndrome and Esophageal Atresia
Dumping syndrome (DS) is frequent in oesophageal atresia (29%). In causing hypoglycaemia, it can be dangerous for neonates. Mechanisms of DS are actually partialy understood.
- Trial name
- DUMTORING (NCT04522193)
- Testing
- Glycemic Holter, gastric emptying scintigraphy, Holter ECG
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Lille
Eosinophilic Esophagitis
Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, characterized by eosinophilic infiltration and gastrointestinal (GI) symptoms.
- Trial name
- NCT01386112
- Testing
- EUR-1100
- Where
- 7 sites in United States
- Volunteers
- 24 people
- Sponsor
- Forest Laboratories
Functional Gastrointestinal Disorders, Infant, Newborn, Diseases
Quantification of Fecal Calprotectin Concentration Difference Between Infants Aged Under 4 Months Old Suffering From Functional Gastrointestinal Disorders (FGID) and Infants Aged Under 4 Months Old Free From Disorders : a Transversal Case-control Monocentric Study
There is a high prevalence of FGID among infants : 30 % for regurgitations, 20 % for colitis , 15 % for functional constipation.This represents a frequent motive for pediatrics consultation : 23 to 28 % of medical consultations…
- Trial name
- Cal-IBS (NCT05936112)
- Testing
- Fecal calprotectin dosage, Questionnaire and interview with parents
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Eosinophilic Esophagitis
Exhaled Nitric Oxide as a Biomarker of Disease Activity in Eosinophilic Esophagitis
There is currently no reliable, noninvasive biomarker for eosinophilic esophagitis (EoE), a chronic allergic diseases characterized by significant infiltration of eosinophils in the esophagus.
- Trial name
- NCT01170234
- Testing
- NIOX MINO® Airway Inflammation Monitor
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Tufts Medical Center
Cancer of Colon, Surgery
Effect of Music Prehabilitation on Preoperative Anxiety Before Surgery
The goal of this multicenter randomized controlled trial is to investigate the effect of music prehabilitation on preoperative anxiety in patients undergoing elective oncological colorectal resection.
- Conditions
- Cancer of Colon, Surgery, Anxiety
- Trial name
- MU-PRIOR (NCT05982184)
- Testing
- Music
- Where
- 5 sites in Netherlands
- Volunteers
- 116 people
- Sponsor
- Erasmus Medical Center
Eosinophilic Esophagitis
Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis
Purpose: To determine whether oral viscous budesonide (OVB) or fluticasone metered dose inhaler (MDI) most effectively treats EoE by improving histologic findings and symptoms, which medication provides a more durable treatment…
- Trial name
- NCT02019758
- Testing
- Oral Viscous Budesonide, Fluticasone MDI
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of North Carolina, Chapel Hill
Gastroesophageal Reflux Disease (GERD), Peptic Ulcers
Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and esophagus. GERD might occur when the lower esophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the…
- Trial name
- NCT00261300
- Testing
- Pantoprazole
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Takeda
Feeding Disorders, Swallowing Disorder
Feeding and Swallowing Problems in Infants With Laryngomalacia
Observational cross-sectional study Infants with laryngomalacia Feeding and swallowing assessment
- Conditions
- Feeding Disorders, Swallowing Disorder, Laryngomalacia
- Trial name
- NCT05337475
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
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