Clinical trials: Gastro-Intestinal Tolerance
Severe Acute Malnutrition
Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
The primary outcome of the study is to identify gastrointestinal tolerance of under-five children with severe acute malnutrition to ready-to-drink high energy (1.5 kcal/ml) and standard energy (1 kcal/ml) oral nutrition…
- Trial name
- NCT04715204
- Testing
- High Energy Oral Nutrition Supplement, Standard Energy Oral Nutrition Supplement, Formula-75/Formula-100
- Where
- 2 sites in Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Gastrointestinal Disease, Inflammatory Bowel Disease (IBD)
Elemental 028 Extra Case Studies
Elemental 028 Extra is a nutritionally complete ACBS approved amino acid-based (elemental) feed designed to provide adequate daily amounts of both macronutrients and micronutrients when used as a sole source of nutrition and to…
- Conditions
- Gastrointestinal Disease, Inflammatory Bowel Disease (IBD), Short Bowel, Malabsorption
- Trial name
- E028E (NCT06877923)
- Testing
- Elemental 028 Extra
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Nutricia UK Ltd
Healthy
Gastrointestinal Tolerance And General Health Status Of Healthy Term Infants Fed A New Infant Formula
The purpose of this study is to assess stool consistency, in combination with additional health-related parameters including gastrointestinal tolerance and health-related quality of life, in a large sample of Chinese infants.
- Trial name
- NCT01370967
- Testing
- Study formula feeding, Human milk feeding, Mixed feeding
- Where
- 24 sites in China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Infant Term Birth
Acceptability and Gastrointestinal Tolerance of a High-Sn-2 Infant Formula
The purpose of this study is to evaluate the effects of term infant formula containing high 2-palmitic vegetable oil on stool composition, stool characteristics and gastrointestinal (GI) Tolerance.
- Trial name
- NCT02598817
- Testing
- Standard Infant Formula
- Where
- 5 sites in Saudi Arabia, United Arab Emirates
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Gastrointestinal Tolerance of Probiotics in Infants
Evaluating the Impact of Synbiotic Supplementation on Infants and Toddlers
Background and Significance: Bifidobacterium longum subspecies infantis (B. infantis) and other infant associated Bifidobacterium (such as Bifidobacterium longum subspecies longum and Bifidobacterium breve) are known to be…
- Trial name
- NCT06746285
- Testing
- Synbiotic Supplement
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Persephone Biosciences
Crohn's Disease
Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease
The purpose of this study is to determine if high doses of vitamin D3 administered orally as adjunct therapy to children with Crohn's disease could improve the outcome of the disease.
- Trial name
- NCT01692808
- Testing
- Vitamin D3 3000 UI daily, Vitamin D3 4000 UI daily
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Premature Infant
Effects Of Not Measuring Gastric Residual Content On Feeding Tolerance In Premature Infants iNFANTS
Omitting evaluation of gastric residual contents prior to feeding very premature infants will increase the feeding intake at 2 weeks, and total caloric intake and growth by 3 weeks, as well as decrease the time required for…
- Trial name
- NCT01965769
- Testing
- No gastric residual evaluation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Florida
Growth, Colic
Safety and Tolerance Study of Alpha-Lactalbumin Enriched and Probiotic-Supplemented Infant Formula in Infants With Colic
The purpose of this study is to evaluate the nutritional adequacy, the digestive tolerance and the effect on colic of an alpha-lactalbumin-enriched and probiotic-supplemented infant formula.
- Trial name
- NCT00929292
- Testing
- Modilac Dahlia 1, Modilac 1
- Where
- 12 sites in France
- Volunteers
- 66 people
- Sponsor
- Sodilac
Short Gut Syndrome
Fiber Food Introduction in Pediatric Short Bowel Syndrome
Short bowel syndrome (SBS) is a rare but challenging condition in which patients have insufficient bowel length to meet fluid, electrolyte, and nutrient requirements without parenteral support.
- Trial name
- NCT05432648
- Testing
- Green bean puree
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Gastrointestinal Tolerance
Behavior of Infants Fed Formula Supplemented With Prebiotics
To observe the effects of partially hydrolyzed formula supplemented with oligosaccharides on symptoms of formula intolerance in healthy term infants.
- Trial name
- NCT02757924
- Testing
- Infant formula supplemented with prebiotics
- Where
- 11 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Gastrointestinal Tolerance of Infant Formula
The study objective is to evaluate the gastrointestinal tolerance of infant formula supplemented with prebiotics.
- Trial name
- NCT02322138
- Testing
- Experimental 1 Infant Formula, Experimental 2 Infant Formula, Reference Group
- Where
- 10 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance, Gastrointestinal Symptoms
Gastrointestinal Symptoms and Tolerance in Infants Fed Goat or Cow's Milk-based Infant Formula
This randomized controlled double-blind study will compare the effect of a commercially available goat milk formula to a cow's milk formula on gastrointestinal symptoms and tolerance, and infections in infants.
- Conditions
- Gastrointestinal Tolerance, Gastrointestinal Symptoms, Infections, Quality of Life
- Trial name
- MESK-2 (NCT07342972)
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula
- Where
- Saudi Arabia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Infant, Gastrointestinal Intolerance
Tolerance and Compliance of Infants Fed an Hydrolyzed Infant Formula
The objective of the study is to assess gastrointestinal tolerance and compliance in infants who require a hydrolyzed formula.
- Trial name
- NCT01573871
- Testing
- Experimental Hydrolyzed infant formula
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Abbott Nutrition
Gastrointestinal Diseases, Feeding Intolerance
Evaluation of the Safe Use and Tolerance of a Peptide-based Formula in a Pediatric Population
The objective of this study is to determine the safe use and tolerance of a peptide-based formula in children with gastrointestinal dysfunction and/or feeding intolerance.
- Trial name
- NCT01191112
- Testing
- Peptide based enteral formula
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Abbott Nutrition
Gastrointestinal Problems
Assessment of Efficacy and Tolerance of a Follow-On Milk Containing a Mixture of Prebiotics Fed to Young Children in Salvador, Bahia, Brazil
This clinical study will evaluate the effect on incidence of diarrhea, respiratory illness, stool patterns and growth of two cow's milk-based beverages for children.
- Trial name
- NCT01177605
- Testing
- Nutritional vanilla flavored beverage - 1) Milk-based beverage containing prebiotics 2) Milk-based beverage containing no prebiotics
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Crohn Disease
The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )
The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relapses) and the quality of life, including levels of physical activity, in children diagnosed Crohn's disease…
- Trial name
- ViDiPeC-2 (NCT03999580)
- Testing
- vitamin D3
- Where
- 7 sites in Canada
- Volunteers
- 55 people
- Sponsor
- Jantchou Prevost
Colon Cancer
Safe, Effective, and More Tolerable 16 Tablets Colon Prep
The purpose of this study is determine if the AB Prep (a 16 tablets colon cleansing prep), is an effective, and safe colon cleansing prep in preparation for colonoscopy, and severe constipation.
- Trial name
- ABP (NCT00817934)
- Testing
- AB PREP
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Long Neck Medical Enterprises
Prematurity, Lactose Intolerance
Lactase Enzyme Supplementation for Growth and Feeding Tolerance in Preterm Infants
Preterm infants commonly experience feeding intolerance, which can delay advancement of enteral feeding and impair early growth.
- Conditions
- Prematurity, Lactose Intolerance, Feeding Intolerance
- Trial name
- NCT07494123
- Testing
- Lactase Enzyme Supplementation
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Infantile Colic
Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
The study is conducted to examine the safety and efficacy of a new infant formula and its effects on the gastrointestinal tolerance in infants suffering from colic.
- Trial name
- Coco (NCT01721850)
- Testing
- control formula, intervention formula 1, intervention formula 2
- Where
- 18 sites in Germany, Italy
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Gastro-Intestinal Tolerance
Tolerance of an Oral Nutritional Supplement(ONS)
The objective of this study is to capture information on gastrointestinal tolerance (GI) of an oral nutritional supplement containing a new protein blend in healthy children aged ≥ 3 to ≤ 10 years.
- Trial name
- NCT01782456
- Testing
- Study Oral Nutritional Supplement
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition