Clinical trials: Gastro-Oesophageal Reflux
Dyspepsia, Heartburn
Bile Reflux Gastropathy: Prevalence and Risk Factors After Therapeutic Biliary Interventions
Bile reflux gastropathy is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to declare if the therapeutic biliary interventions cause bile reflux gastropathy, and to…
- Conditions
- Dyspepsia, Heartburn, Bile Reflux
- Trial name
- NCT05131802
- Testing
- upper GIT endescopy
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Zagazig University
GERD, Gastroesophageal Reflux
Compassionate Use of Domperidone for Refractory Gastroparesis
The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who have failed all the standard…
- Conditions
- GERD, Gastroesophageal Reflux, Gastroparesis
- Trial name
- NCT04699591
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jose Cocjin
Gastro Esophageal Reflux
Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids)
This study aims to determine the prevalence of symptomatic gastroesophageal reflux disease (GERD) in children aged 8-9 years and 12-13 years in the Czech Republic.
- Trial name
- Czech GERDKids (NCT07482969)
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Motol
Helicobacter Pylori Infection, Peptic Ulcer
The Revolutions of Helicobacter Pylori Infection, Bacterial Density, and Histological Features After Antrectomy
Helicobacter pylori (HP) is a gram-negative bacillus responsible for one of the most common infections found in humans worldwide.
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer, Bile Reflux, Gastritis
- Trial name
- NCT00441831
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Mackay Memorial Hospital
Gastroesophageal Reflux Disease
Neonatal Gastro-Esophageal Reflux Disease (GERD) Management Trial
The overall purpose of the investigator's study is to evaluate the causes of and treatment for feeding difficulty in infants with Gastro-esophageal Reflux Disease (GERD). New treatments can be possible only if the cause is known.
- Trial name
- GMT (NCT02486263)
- Testing
- Study Arm - acid suppression plus feeding bundle, Conventional arm - acid suppression only
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Sudarshan Jadcherla
Cerebral Palsy, GORD
Gastro-oesophageal Reflux and NeuroDisability (Cerebral Palsy) in CHILDren
This study assesses the content validity of the PGSQ for parents/carer of children with cerebral palsy and GORD, including features such as readability, face validity and acceptability for completion.
- Conditions
- Cerebral Palsy, GORD, Pediatrics, GERD in Children
- Trial name
- GRANDCHILD (NCT04293107)
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Esophageal Motility Disorders, Gastro-esophageal Reflux
Pressure and Flow Study Before and After Treatments for EMD. The pFlow Study
Pressure and flow (PF) analysis allow a detailed report on the bolus passing for each segment of the esophagus. This approach has evidence in oropharyngeal dysphagia, post reflux surgery dysphagia, gastroesophageal reflux in…
- Trial name
- pFlow (NCT03904004)
- Testing
- Peroral endoscopic myotomy, Neumatic dilatation, Botulinum toxin injection
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacion Miguel Servet
Gastro-oesophageal Reflux
Influence of Airway Clearance Techniques on GOR in Infants
The purpose of this study is to determine whether Assisted Autogenic Drainage (AAD) or bouncing combined with Assisted Autogenic Drainage (BAAD), induces or aggravates acid and non-acid gastro-oesophageal reflux in infants under…
- Trial name
- NCT03346174
- Testing
- AAD, BAAD
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Vrije Universiteit Brussel
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gastro -Oesophagal Reflux
Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3-Year Follow-up Study of Randomized Controlled Trial.
Long-term results following laparoscopic and open Nissen fundoplication for gastro-oesophageal reflux will be objectively assessed in a selected population of patients already included in a randomized controlled trial comparing…
- Trial name
- NCT00259961
- Testing
- open fundoplication, laparoscopic fundopliaction
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Gastro-Oesophageal Reflux
Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery
The aim of this trial was to characterise the intra and post operative metabolic, endocrine and inflammatory response to laparoscopic fundoplication in children.
- Trial name
- NCT00231543
- Testing
- Laparoscopic fundoplication, open Nissen fundoplication
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Gastro-oesophageal Reflux
Influence of IPV on GOR in Infants From 0 to 12 Months.
The purpose of this study is to determine whether Intrapulmonary Percussive Ventilation ( airway clearance technique) provokes or aggravates gastro-oesophageal reflux in infants from 0 to 12 months.
- Trial name
- NCT02124863
- Testing
- Intrapulmonary Percussive Ventilation
- Where
- Belgium
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative
Antireflux Suture In One Anastomsis Gastric Bypass
To prevent refulx symptoms in a type of bariatric surgery, a suture is taken.there is no enough evidence in support of or against the suture.
- Trial name
- NCT07148492
- Testing
- Antireflux suture, No Antireflux suture
- Where
- Pakistan
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Gastro-esophageal Reflux
Safety Study of Airway Clearance Techniques in Infants.
The purpose of this study is to determine whether three airway clearance techniques ( Bouncing, Assisted Autogenic Drainage ( AAD) and bouncing and AAD) provoke or aggravate gastro-esophageal reflux in infants under the age of 1…
- Trial name
- NCT02128867
- Testing
- Assisted Autogenic Drainage (AAD), bouncing and AAD, bouncing
- Where
- Belgium
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Gastro Esophageal Reflux
Effect of Magnesium Alginate in Infants With Gastroesophageal Reflux.
Recurrent regurgitation stress the infants and their parents and often results in an inappropirate use of PPI prescription in infancy.
- Trial name
- NCT03881722
- Testing
- Mg alginate
- Where
- Italy
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Laryngomalacia, Gastro Esophageal Reflux
Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia
Laryngomalacia (LM) is the most common cause of stridor in infants. Symptoms of gastroesophageal reflux (GER) are often seen in the setting of LM; therefore, acid suppression therapy (AST) has been empirically used in the…
- Trial name
- NCT04614974
- Testing
- Famotidine, Speech Language Therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Reema Padia
Digestive System Disease
Clinical Applications of Domperidone in Patients With Delayed Gastric Emptying
The purpose of the study is to treat patients with on-going slow stomach emptying(gastroesophageal reflux disease), who have failed to respond to standard therapy
- Trial name
- NCT01844622
- Testing
- Domperidone
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Mt. Sinai Medical Center, Miami
Reflux
Prospective Randomized Trial Evaluating the Utility of Esophageal Stitches During Laparoscopic Fundoplication
This is a prospective trial of the utility of esophageal stitches during fundoplication. The hypothesis is that recurrence rate may be different with or without the esophageal stitches.
- Trial name
- NCT01509352
- Testing
- esophageal stitches during fundoplication, no esophageal stitches placed during fundoplication
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Mercy Hospital Kansas City
Digestive System Disorder, Dyspepsia
Domperidone in Treating Patients With Gastrointestinal Disorders
This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea…
- Conditions
- Digestive System Disorder, Dyspepsia, Esophagitis, Gastroesophageal Reflux Disease
- Trial name
- NCT01696734
- Testing
- Domperidone, Questionnaire Administration
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- M.D. Anderson Cancer Center