Clinical trials: Gender Dysphoria
Gender Dysphoria, Transgender
Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy
The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to: 1. Optimize techniques for processing and cryopreserving testicular tissue. 2.
- Trial name
- NCT05829928
- Testing
- Infectious Disease Testing, Gonadal Tissue Removal
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pittsburgh
Gender Dysphoria
Gender Dysphoria: Epidemiological Data
Retrospective study in a single academic regional transgender referral center. data from the cohort follow-up in CHRU de Nancy
- Trial name
- DyGenEpi (NCT04573127)
- Testing
- descriptive study
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria
Chest Dysphoria in Transmasculine Spectrum Adolescents
The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in…
- Trial name
- NCT04195659
- Testing
- Mastectomy and chest masculinization
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Northwestern University
Gender Dysphoria
The Relation of GnRH Treatment to QTc Interval in Transgender Females
Background: The QT interval of the electrocardiogram (ECG), corrected for heart rate (QTc), is a measure of the duration of ventricular repolarization and is a widely used marker of ventricular arrhythmia risk.
- Trial name
- NCT03078829
- Testing
- Treatment with a GnRh agonists
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, San Francisco
Transgender Individuals, Gender Incongruence
Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study
The goal of this observational study is to understand the factors influencing the well-being and health of transgender and gender-diverse (TGD) individuals undergoing gender-affirming therapies in Switzerland.
- Trial name
- SPECTRA (NCT06774053)
- Testing
- Group A (start of GAHT), Group B (on-going GAHT), Group C (GAS)
- Where
- 3 sites in Switzerland
- Volunteers
- 600 people
- Sponsor
- University Hospital, Basel, Switzerland
Gender Incongruence, Cardiovascular Disease (CVD) Risk Factors
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy
Gender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the…
- Trial name
- CARMEN (NCT07128771)
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Gender Dysphoria
Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender Dysphoria
Gender dysphoria (GD) is a significant suffering lasting more than 6 months in a subject, with regard to the discrepancy felt between his or her gender identity and his or her birth sex.
- Trial name
- TRANSADO (NCT06351501)
- Testing
- hormonal treatment with cross sex hormones (testosterone or oestrogenes) started at 14 years old +/- 6 months, Cross sex hormones ( œstrogenes or testosterone) started at 15.5 years old +/- 6 months
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gender Dysphoria
Gender Dysphoria Among Adolescents (Norwegian Title: Kjønnsdysfori Blant Ungdom)
The aim of this study is to explore how gender dysphoria is experienced among adolescents aged 13 - 18 from a clinical population. The method is qualitative, with a phenomenological approach.
- Trial name
- NCT03643120
- Testing
- Qualitative interview
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Gender Identity, Gender Dysphoria
Pubertal Blockade and Hormone Therapy in Transgender Youth
This study will enroll female-to-male transgender youth who are and are not on a puberty blocker (gonadotropin-releasing hormone analogue) at baseline and 1 and 12 months after starting testosterone.
- Conditions
- Gender Identity, Gender Dysphoria, Gender Identity Disorder in Adolescence and Adulthood
- Trial name
- PUBErTY (NCT03557268)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Gender Dysphoria, Adolescent
Psychological Vulnerabilities and Transgender Adolescents: A Descriptive Epidemiology Study
The number of adolescents engaging in a transidentity journey has been increasing rapidly over the last decade. However, the knowledge of the medical world concerning the specificities of these adolescents is still too little in…
- Trial name
- VATED (NCT05126134)
- Testing
- KSADS (Kiddie Schedule for Affective Disorders and Schizophrenia)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Toulouse
Testicular Cancer, Testicular Torsion
Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
To analyze the short and long term postoperative clinical outcome and patient satisfaction of silicone gel-filled testicular implants.
- Conditions
- Testicular Cancer, Testicular Torsion, Gender Dysphoria, Undescended Testes
- Trial name
- NCT05097820
- Testing
- Placement of testicular prosthesis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Gender Dysphoria, Gender Identity Disorder
TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery Settings
Trans (i.e., transgender, transsexual) individuals experience a gender that does not match their sex assigned at birth (Gender Incongruence), which can lead to distress called gender dysphoria (formerly known as transsexualism).
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT03872648
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Gender Dysphoria
Demographic Characteristics and Psychosocial Health of Transgender People
To study demographic characteristics of subjects referred to endocrine care for gender dysphoria and their psychosocial health
- Trial name
- DyGeDem (NCT04554849)
- Testing
- Gender dysphoria psychosocial health
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria, Adolescent
Fertility Preservation for Transfeminine Adolescents Via Semen Cryopreservation or Testicular Sperm Extraction
The goal of this observational cohort study is to identify and predict parameters for successful testicular sperm extraction (TESE) procedures or semen cryopreservation more accurately and to evaluate the decision making process…
- Trial name
- TESE (NCT06400199)
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Gender Dysphoria, Transgender
Ovarian Tissue Cryopreservation in the Setting of Gender-affirming Therapy
The goal of this study is to learn about fertility preservation in the gender-diverse community. The main objectives it aims to understand are to: 1.
- Trial name
- NCT05863676
- Testing
- Oophorectomy, Infectious Disease Testing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Transgenderism, Gender Dysphoria
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
- Conditions
- Transgenderism, Gender Dysphoria, Insulin Sensitivity
- Trial name
- PUBERTY (NCT04596592)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Transgender, Gender Dysphoria in Adolescents and Adults
The Effect of Gender-affirmative Measures on Breast Perception in Trans Men
Breast dysphoria in transmasculine or genderdiverse individuals is a distinct psychological burden associated with depression, anxiety and suicidality.
- Trial name
- TRANSBREAST (NCT07252687)
- Testing
- quality of life questionnaire- iTransQoL, chest dysphoria measure
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University Innsbruck
Gender Dysphoria, Adolescent
Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Recommendations regarding contraceptive counseling and reproductive health differ amongst transgender and gender diverse (TGD) youth compared to cis-gender youth.
- Trial name
- NCT05726903
- Testing
- Depo-subQ Provera Injectable Product
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gender Incongruence
Optimizing Individual Health Care for Young People With Gender Incongruence
This observational study focuses on evaluating the effect of the current health care program for Danish children and adolescents with gender incongruence, which was established in January 2016.
- Trial name
- NCT06573177
- Testing
- Referral to the gender identity service.
- Where
- Denmark
- Volunteers
- 1,300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gender Dysphoria
Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans
Transgender Veterans (trans Vets) frequently experience gender dysphoria or distress related to discord between their gender identity and birth sex.
- Trial name
- NCT06615401
- Where
- United States
- Volunteers
- 986 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development