Clinical trials: General Health and Wellness
Celiac Disease in Children
"Adding DNA-test for Screening of HLA-DQ2 and DQ8 to Improve Early Diagnosis of Celiac Disease"
Celiac Disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten containing cereals from the normal diet, among others wheat, rye and barley.
- Trial name
- GLUTEN-GEN (NCT06179121)
- Testing
- DNA test for screening HLA-DQ2 and DQ8 from dried blood spots to early detect Celiac Disease
- Where
- Netherlands
- Volunteers
- 508 people
- Sponsor
- Leiden University Medical Center
Sepsis
Prevention of Infection in Indian Neonates - Phase II Probiotics Study
India, with one of the world's largest populations, continues to struggle with extremely high infant and neonatal mortality rates.
- Trial name
- NCT00518596
- Testing
- Probiotic supplementation (Lactobacillus plantarum)
- Where
- 3 sites in India
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Learning, Comprehensive Wellbeing
Future School of Comprehensive Well-Being
Good physical, mental and social health, particularly in childhood and early adolescence, are powerful predictors of positive life trajectories.
- Conditions
- Learning, Comprehensive Wellbeing, Social Wellbeing, Physical Wellbeing
- Trial name
- SchoolWell (NCT07906522)
- Testing
- Comprehensive well-being pedagogy intervention for primary and lower secondary school students
- Where
- 6 sites in Finland
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Age 65 and Older, Polypharmacy
Effect of Longitudinal Care in Primary Health Care: An Analysis From the Patient's Perspective
Objective To explore and describe the opinions of Primary Health Care chronically ill users regarding being cared for over time by the same reference professional.
- Conditions
- Age 65 and Older, Polypharmacy, Cronic Lung Disease, Mental Disorder
- Trial name
- CUALIPRIM (NCT07320053)
- Where
- 2 sites in Spain
- Volunteers
- 26 people
- Sponsor
- IBS Granada
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Stroke
Effects of Touch Massage in the Sub-acute Phase After Stroke
The aim is to study effects of touch massage in the sub-acute phase after stroke in two main areas; general health and independence.The hypothesis are that; touch massage in the sub-acute phase after stroke decreases anxiety and…
- Trial name
- MEST (NCT01883947)
- Testing
- Touch massage, non-TENS
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Shigella, Child
Enterics for Global Health (EFGH)
Diarrhea remains a leading cause of death among young children, with the majority of diarrhea deaths occurring in low- and middle-income countries.
- Conditions
- Shigella, Child, Diarrhea
- Trial name
- EFGH (NCT06047821)
- Where
- 33 sites in Bangladesh, Kenya and 5 more
- Volunteers
- 9,800 people
- Sponsor
- University of Washington
Preterm Delivery, Hypothermia
Randomized Controlled Trial of Social Network Targeting in Honduras
Social network targeting strategies can be used to improve the delivery and uptake of health interventions. We will enroll approximately 30,000 individuals into a randomized controlled trial of different targeting algorithms in…
- Conditions
- Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection
- Trial name
- NCT02694679
- Testing
- CBNH
- Where
- 2 sites in United States, Honduras
- Volunteers
- 31,195 people, healthy volunteers welcome
- Sponsor
- Yale University
Health Services Research
Using Anonymous Data From A Digital Tool for Medical History-Taking To Improve Healthcare Services
This study aims to understand how people use a mobile app that helps them record their symptoms before going to the doctor. Patients use the app on a tablet or other digital device.
- Trial name
- NCT06761105
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Goettingen
Preeclampsia, Eclampsia
RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil
The perinatal morbidity and mortality rates for Brazil are five to ten-fold higher than those reported for upper income countries.
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome, Pregnancy
- Trial name
- NCT00097110
- Testing
- Vitamin C and E
- Where
- Brazil
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Chronic Diseases
Evaluating Community Health Centers' Adoption of a New Global Capitation Payment
The investigators are conducting a prospective analysis of the Alternative Payment Methodology (APM) demonstration project sites. The investigators' goal is to conduct a cross project analysis of findings.
- Trial name
- eCHANGE (NCT02637869)
- Testing
- Alternative Payment Model
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Acute Disease, Nursing Care
Nurse vs General Practitioner Care for Patients Requesting Same Day Consultations in Primary Care
The purpose of this study is to compare the effectiveness of nursing care in relation to usual medical care in adult patients who demand to be visited the same day in Primary Care Teams in Catalonia, as it is suggested in other…
- Conditions
- Acute Disease, Nursing Care, Ambulatory Care, Family Practice
- Trial name
- NCT00461201
- Testing
- Nurse practitioner care of patients
- Volunteers
- 1,640 people
- Sponsor
- Catalan Institute of Health
Stress, Generalized Anxiety
Enhancing Health in Rural Populations: Music as Therapy
The goal of this clinical trial is to learn whether a music-based intervention can improve mental and physical health and strengthen coping skills among adults living in residential care settings in northern Arizona.
- Conditions
- Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
- Trial name
- NCT07538427
- Testing
- Music Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Intestinal Diseases, Parasitic
Postpartum Deworming: Improving Breastfeeding and Optimizing Infant Growth
Women of reproductive age are considered a high-risk group for worm infections by the World Health Organization. Maternal infection and anemia contribute to infant malnutrition by affecting milk quality and quantity, and duration…
- Trial name
- NCT01748929
- Testing
- Albendazole
- Where
- Peru
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Trauma, Trauma Blunt
Trauma Registry in Villavicencio, Colombia
Introduction: Injuries are a leading cause of mortality worldwide. It is necessary to know the incidence of injuries, mechanisms of wounds, therapy provided, and outcomes.
- Conditions
- Trauma, Trauma Blunt, Penetrating Wounds, Severe Trauma
- Trial name
- TRaVi (NCT05954936)
- Testing
- Risk factor
- Where
- Colombia
- Volunteers
- 250 people
- Sponsor
- Hospital Departamental de Villavicencio
Malnutrition, Anemia
Microfinance Institutions as a Platform for Global Health
This study will analyze data from a program run by an microfinance institution (MFI) in Haiti from 2011-2012 where the MFI delivered health goods to some of the villages where it operates.
- Trial name
- NCT02808117
- Testing
- MNP
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- Columbia University
Dental Caries
Population-centered Risk- and Evidence-based Dental Inter-professional Care Team
The main goal of the payment and delivery system reform is to reduce disparities in oral health and dental care access of low-income mothers and children living in rural Oregon counties.
- Trial name
- PREDICT (NCT02312921)
- Testing
- PREDICT
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Meningitis, Encephalitis
BIGlobal Intervention Study: Improving Diagnosis and Management of Suspected Brain Infections Globally
Background: Patients with suspected brain infections pose major challenges to low and middle income countries, including their disproportionately high burden, diverse causes with inadequate surveillance, requirement for invasive…
- Conditions
- Meningitis, Encephalitis, Abscess Brain
- Trial name
- NCT04190303
- Testing
- Pragmatic, multi-component package
- Where
- 4 sites in Brazil, India and 1 more
- Volunteers
- 2,233 people
- Sponsor
- University of Liverpool
Mental Health Issue, Stigma, Social
Implementing an Education- and Health System Task-shifting Approach for Child Mental Health Promotion in Uganda
This study will adapt a school version (mhGAP-IGs) of the World Health Organization´s (WHO) "Mental Health Gap Action Programme Intervention Guide" (mhGAP).
- Conditions
- Mental Health Issue, Stigma, Social, Child Development, Child Abuse
- Trial name
- TREAT (NCT06275672)
- Testing
- Adapted version of the mhGAP-IG
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies