Clinical trials: General Medicine
Quality Control
The Effectiveness of a Nationwide Mandatory Accreditation in General Practice in Denmark
Accreditation is used increasingly in health systems worldwide. However, there is a lack of evidence of the effectiveness of accreditation.
- Trial name
- ACIAP (NCT02762240)
- Testing
- DHQP 2016, DHQP 2018
- Volunteers
- 1,900 people
- Sponsor
- University of Southern Denmark
Colorectal Cancer
A Trial of the Implementation of iFOBT in General Practice
Background Colorectal cancer (CRC) is common, and a leading cause of cancer death. The evaluation of patients suspected to have CRC is difficult due to poorly predictive alarm symptoms and many patients present with…
- Trial name
- NCT02308384
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 825 people
- Sponsor
- University of Aarhus
Osteoporosis
Post Marketing Surveillance For General Drug Use To Assess the Safety And Efficacy Profile Of Viviant In Usual Practice
This survey is conducted for preparing application material for re examination under the Pharmaceutical Affairs Laws and its Enforcement Regulation, and assessing the safety and efficacy profiles of VIVIANT in usual practice…
- Trial name
- NCT01793142
- Testing
- Viviant
- Where
- 60 sites in South Korea
- Volunteers
- 3,430 people
- Sponsor
- Pfizer
SARS-CoV Infection
Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
The virological diagnosis of SARS-CoV-2 infection is pivotal for the control of the outbreak by large screening of a- or pauci-symptomatic subjects.
- Trial name
- AutoCoV (NCT04859023)
- Testing
- saliva sample combined to an anterior nare self-swabbing (Self-samples), saliva sample (Self-sample), Survey of SARS-COV-19 knowledge
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Alcohol Use Disorder
Promoting Medications for Alcohol Use Disorder on the General Medicine Service
Medications for Alcohol use disorder (MAUD) (acamprosate, naltrexone, and disulfiram) remain underutilized despite guideline recommendations and rising alcohol-related morbidity and mortality.
- Trial name
- NCT04287790
- Testing
- audit and feedback, educational meetings, and academic detailing to promote medication receipt, Acamprosate, naltrexone, or disulfiram
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Yale University
Heart Failure
Electronic Transmission of Laboratory and Adherence Records of Heart Failure Patients to General Practitioners Screen
Patients with heart failure (HF) need multiple guideline-directed medications to control the systolic and/or diastolic ventricular dysfunction.
- Trial name
- LabAdhDoc (NCT04326101)
- Testing
- Transmission of adherence records
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland
Patient Safety, Inappropriate Prescribing
A Randomised Pilot Study of the REVISiT Intervention
In 2012, the General Medical Council (GMC) funded PRACtICe (PRevalence And Causes of prescrIbing errors in general practiCe) study, reported that 1 in 20 prescriptions in general practice were found to have a prescribing or…
- Conditions
- Patient Safety, Inappropriate Prescribing, Medication Errors
- Trial name
- NCT04586595
- Testing
- REVISiT intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Infertility, Female
Intracervical Anasthesia in Outpatient Hystroscopy, Can Procedure be Completed Diagnostic and Therapeutic With no Need to General Anaesthesia
Single blind randomized controlled study in which 80 patients coming for hystroscopy due to multiple indication as infertility, AUB and missed IUD were assigned for our study.
- Trial name
- NCT03747692
- Testing
- study group, control group
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS)
A Study to Gather Information About Overall Occurrence and New Cases of Dravet and Lennox-Gastaut Syndromes in Children, Teenagers and Adults in Spain
The main aims of this study are to gather information about how many children, teenagers and adults in Spain have been diagnosed with Dravet syndrome and Lennox-Gastaut syndrome as well as to learn about the number of new Dravet…
- Trial name
- DRALEGA (NCT05982717)
- Testing
- No intervention
- Where
- 4 sites in Spain
- Volunteers
- 237 people
- Sponsor
- Takeda
Cancer, Side Effect of Drug
Radiopharmaceuticals Analysis for Detailed Insights And INternational Tracking of Safety
Little is known about cancer therapy-related radiopharmaceuticals drugs safety. Here the investigators use VigiBase (http://www.vigiaccess.org/), the World Health Organization (WHO) database of individual safety case reports, to…
- Trial name
- RADIANTS (NCT06483685)
- Testing
- Radiopharmaceuticals drugs
- Where
- France
- Volunteers
- 500,000 people
- Sponsor
- University Hospital, Caen
Respiratory Tract Diagnoses (ICPC-2), Prescriptions of Antibiotics by General Practitioners
Respiratory Tract Infections and Prescription Drugs in Children and in Pregnancy
The main objective is to investigate the incidence of Respiratory Tract Infections (RTIs) and antibiotic prescriptions in children and during pregnancy, the different drugs chosen by their doctors according to diagnosis, and…
- Conditions
- Respiratory Tract Diagnoses (ICPC-2), Prescriptions of Antibiotics by General Practitioners, Prescriptions of ATC J01 and R Drugs in Participants
- Trial name
- NCT01109589
- Where
- Norway
- Volunteers
- 60,000 people
- Sponsor
- University of Oslo
Quality Improvement in Patient Handoff
Quality Improvement in Handover of General Internal Medicine In-patients
Miscommunication during patient handover can jeopardize patient safety and is the focus of Quality Improvement initiatives by many organizations.
- Trial name
- NCT01796756
- Testing
- Handover program
- Where
- Canada
- Volunteers
- 1,168 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
SARS-CoV-2 Infection
A Study to Learn About PAXLOVID (a Commercial Medicine) In People With COVID-19
The purpose of this post marketing observational study is to learn about the safety and effects of the commercial medicine (called PAXLOVID) for the treatment of COVID-19.
- Trial name
- NCT05263908
- Testing
- nirmatrelvir / ritonavir
- Where
- Japan
- Volunteers
- 3,346 people
- Sponsor
- Pfizer
Childhood Absence Epilepsy
Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures
The primary purpose of this study is to assess the efficacy of Cannabidiol Oral Solution in the treatment of pediatric participants with treatment-resistant childhood absence seizures.
- Trial name
- NCT03336242
- Testing
- Cannabidiol Oral Solution
- Where
- 11 sites in United States
- Volunteers
- 20 people
- Sponsor
- Radius Pharmaceuticals, Inc.
Epilepsy
Evaluation and Treatment of Patients With Epilepsy
This protocol has three purposes: 1) to screen patients with seizures for participation in research studies of NINDS s Clinical Epilepsy Section (CES), 2) to follow the natural course of seizure disorders, and 3) to train CES…
- Trial name
- NCT00013845
- Where
- United States
- Volunteers
- 1,278 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Death
General Practitioners' Felt With Their Patients' Death (REGIDAQ)
Very few studies are dealing with the way general practitioners feel the death of their patients. Main studies about that subject are qualitative.
- Trial name
- REGIDAQ (NCT03272035)
- Where
- France
- Volunteers
- 481 people
- Sponsor
- University Hospital, Limoges
Age 65 and Older, Polypharmacy
Effect of Longitudinal Care in Primary Health Care: An Analysis From the Patient's Perspective
Objective To explore and describe the opinions of Primary Health Care chronically ill users regarding being cared for over time by the same reference professional.
- Conditions
- Age 65 and Older, Polypharmacy, Cronic Lung Disease, Mental Disorder
- Trial name
- CUALIPRIM (NCT07320053)
- Where
- 2 sites in Spain
- Volunteers
- 26 people
- Sponsor
- IBS Granada
Dravet Syndrome (DS)
A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome
This is an open-label, single-center study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of intrathecal RC001 in patients with Dravet syndrome aged 2 to 18 years.
- Trial name
- NCT07675746
- Testing
- RC001 injection-Dose Escalation Cohort, RC001 injection-Fixed Dose Cohort
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Point-of-care Ultrasound
The Clinical Impact of POCUS Use in General Practice
Being a hybrid type 2 effectiveness-implementation study, this study aims to simultaneous assess the clinical effectiveness of the introduction of point-of-care unltrasound in general practice and to measure the impact of the…
- Trial name
- NCT05523882
- Testing
- point-of-care ultrasound
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Health Services Research
Using Anonymous Data From A Digital Tool for Medical History-Taking To Improve Healthcare Services
This study aims to understand how people use a mobile app that helps them record their symptoms before going to the doctor. Patients use the app on a tablet or other digital device.
- Trial name
- NCT06761105
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Goettingen