Clinical trials: Genotyping Techniques
Pain, Other Surgical Procedures
Influence of Genotype of CYP2C9 on Clinical Efficacy and Pharmacokinetics of Piroxicam After Lower Third Molar Surgery
Pharmacogenetics is an area of Pharmacology that studies the contribution of genetic factors to individual responses to drugs. This branch of science involves the variability in pharmacodynamics and pharmacokinetics through the…
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth, Cytochrome P450 CYP2C9 Enzyme Deficiency
- Trial name
- NCT02450487
- Testing
- Piroxicam
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Genotyping Techniques
Spartan Cube CYP2C19 Inter Laboratory Reproducibilty Study
The study verifies that the Spartan Cube CYP2C19 System generates reproducible results under multi-variant conditions including test site (three different test sites), operators (two operators per site), testing days (five…
- Trial name
- NCT04473573
- Testing
- Spartan Cube CYP2C19 System
- Where
- 3 sites in Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.
Colorectal Cancer, Precancerous Condition
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib may keep polyps and colorectal cancer from forming in patients with familial adenomatous polyposis.
- Trial name
- NCT00685568
- Testing
- celecoxib
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- M.D. Anderson Cancer Center
Epilepsy
Genetic Diagnosis and Personalized Medicine for Patients With Epilepsy
Background Epilepsy is a common neurological disorder. It affects 50 million people worldwide and has the highest incidence in pediatric age.
- Trial name
- NCT06321822
- Testing
- Whole exome sequencing (WES)
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Infection
Impact of Genotyping P450 2C19 on Hospitalization Period
Monocentric study with the objective to evaluate the impact of genotyping CYP2C19 on the hospitalization period. The genotyping will permit to adapt at best the Voriconazole posology.
- Trial name
- PHARMACOGEN (NCT03554239)
- Testing
- genotyping
- Sponsor
- University Hospital, Toulouse
Genotyping Techniques
Method Comparison Study of the Spartan FRX CYP2C19 Genotyping System Against Bi-directional Sequencing
The Spartan FRX CYP2C19 Test System (hereafter referred to as the 'FRX System') is a qualitative in vitro diagnostic test for the identification of a patient's CYP2C19 *2, *3 and *17 genotypes from genomic DNA obtained from…
- Trial name
- NCT01718535
- Testing
- Spartan FRX CYP2C19 Test System
- Where
- Canada
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.
Genotyping Techniques
Spartan Cube CYP2C19 Method Comparison Study
The aim of the study is to demonstrate concordance (percent agreement) between results produced by the Spartan CYP2C19 system and bi-directional sequencing.
- Trial name
- NCT04473586
- Testing
- Spartan Cube CYP2C19 System
- Where
- Canada
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.