Clinical trials: Geriatric Disorders
Autism
Open Label of Clinical Trial of Sulforaphane in Children With Autism
This is an open-label, 4-month study examining the effects of Sulforaphane (SF) on behavior in children with ASD and the correlation between behavior change and urinary metabolites.
- Trial name
- NCT02654743
- Testing
- Sulforaphane
- Volunteers
- 21 people
- Sponsor
- University of California, San Francisco
Yellow Fever Immunization
A Phase III Control Study of the Safety and Immunogenicity of vYF in Pediatric Population
The purpose of this study is to determine whether vYF (investigational vaccine) is safe and can help the body to develop antibodies (immunogenicity) compared with Stamaril vaccine and YF-VAX vaccine (both licensed vaccines) and…
- Trial name
- NCT07103148
- Testing
- Yellow fever vaccine (live), Measles, combinations with mumps and rubella, live attenuated
- Where
- 15 sites in Honduras, Mexico and 1 more
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Sanofi
Asthma
Study of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder Inhaler
This study is to evaluate the safety and efficacy of fluticasone propionate and fluticasone propionate salmeterol in pediatric participants with a documented history of persistent asthma.
- Trial name
- NCT02980133
- Testing
- Fluticasone Propionate, Fluticasone Propionate/Salmeterol
- Where
- 118 sites in United States, Georgia and 3 more
- Volunteers
- 841 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Colon Cancer, Frailty
Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)
The purpose of the study is to investigate whether an extended program (ERAS 3.0) initiated hospital discharge, can improve recovery in elderly, frail patients who have undergone surgery for colon cancer.
- Trial name
- NCT06802991
- Testing
- ERAS 3.0 (Enhanced Recovery After Surgery)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital at Herlev
Oesophagitis, Eosinophilic
Intravenous Mepolizumab In Children With Eosinophilic Esophagitis
This study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous mepolizumab in pediatric subjects with eosinophilic esophagitis.
- Trial name
- NCT00358449
- Testing
- mepolizumab
- Where
- 29 sites in United States, Australia and 2 more
- Volunteers
- 84 people
- Sponsor
- GlaxoSmithKline
Influenza
Study to Evaluate the Safety and Immunogenicity of GSK Biological Pandemic Candidate Influenza Vaccine (H1N1) in Children
The objective of this study is to evaluate the safety and immunogenicity study of GSK Biologicals' pandemic influenza candidate vaccine (GSK2340272A) in children aged 3 to 9 years.
- Trial name
- NCT01014091
- Testing
- GSK pandemic vaccine GSK2340272A
- Where
- 3 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Graft Versus Host Disease
A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies
This is a single group, Phase 4, single-arm post-marketing study for treatment. The purpose of this study is to verify the pharmacokinetics, efficacy, and safety of belumosudil mesylate tablets in Chinese adolescent participants…
- Trial name
- NCT06616415
- Testing
- Belumosudil
- Where
- 2 sites in China
- Volunteers
- 6 people
- Sponsor
- Sanofi
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 3
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER3 (NCT05587725)
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Monash University
Hepatitis A, Immunodeficiency
Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in HIV-infected People
Approximately 400 HIV-infected participants aged 1-50 years old will be recruited according to the inclusion and exclusion criteria. Among them, more than 180 participants will be recruited in the immunogenicity and safety study.
- Conditions
- Hepatitis A, Immunodeficiency, HIV Infections
- Trial name
- NCT06576024
- Testing
- 2 doses of HAV, At least one dose of HAV
- Where
- China
- Volunteers
- 392 people
- Sponsor
- LiuZhou People's Hospital
Aromatherapy, Test Anxiety
The Effect Of Aromatherapy Applied To Children Aged 9-12 On Exam Anxiety, Attention Deficit and Academic Success
This study was planned to examine the effects of aromatherapy applied to children aged 9-12 on exam anxiety, attention deficit and academic success. The study was conducted as single blind.
- Conditions
- Aromatherapy, Test Anxiety, Attention Deficits, Academic Achievement
- Trial name
- NCT06791785
- Testing
- Before Application, Before the 1st Written Exam, End of Term
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Severely Malnourished Infants Who Are Less Than 6 Months Old
Rehabilitation of Malnourished Infants With F-100 or Diluted F-100
Hypothesis: During rehabilitation phase of management of severe acute malnourished Bangladeshi infants less than 6 months old, rates of weight gain will be significantly more in children fed F-100 and diluted F-100 compared to…
- Trial name
- NCT01558440
- Testing
- Infant Formula, F-100, Diluted F-100
- Where
- Bangladesh
- Volunteers
- 132 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Ventilator-Induced Lung Injury
Mechanism Study of Ventilator-Induced Lung Injury in Elderly People.
1. We collect lung tissues from patients with different ages and confirm that KLK8 expression is positively correlated with age. 2.
- Trial name
- NCT06367946
- Testing
- mechanical ventilation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Radio Dermatitis, Mucositis Oral
Using Red Light Therapy to Ease Skin Side Effects and Mouth Side Effects, in Children and Young People Aged 0 to 16 Years Old, Receiving Radiotherapy
The goal of this interventional study is to see if the daily use of red light therapy called photobiomodulation can help sore skin and sore mouths in children having radiotherapy.
- Conditions
- Radio Dermatitis, Mucositis Oral, Oesophagitis
- Trial name
- RADIANT (NCT07183267)
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- The Christie NHS Foundation Trust
Hepatitis C
An Open-Label Study of the Effect of Telaprevir in Combination With Peginterferon Alfa-2b and Ribavirin in Pediatric Subjects Infected With Hepatitis C Virus
The purpose of this study is to assess the safety, efficacy, and pharmacokinetics in a carefully monitored cohort of pediatric subjects infected with hepatitis C virus (HCV) on a telaprevir-based regimen in Part A and with dose…
- Trial name
- NCT01701063
- Testing
- Telaprevir, Peginterferon alfa-2b, Ribavirin
- Where
- 23 sites in United States, Belgium and 4 more
- Volunteers
- 42 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Dengue, Dengue Hemorrhagic Fever
Study of a Booster Injection of Pentaxim™ Vaccine Administered With Dengue Vaccine in Healthy Toddlers
The aim of the study was to assess whether the second CYD dengue vaccination could be administered concomitantly with the booster vaccination of a pediatric combination vaccine (Pentaxim™) during the same day visit but in 2…
- Trial name
- NCT01411241
- Testing
- Live, attenuated, recombinant dengue serotype 1, 2, 3, and 4 virus, DTaP IPV//Hib vaccine, Measles, mumps, and rubella vaccine
- Where
- 4 sites in Mexico
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Congenital Heart Disease, Postoperative Care
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach
The purpose of this clinical trial is to learn about the effects of a nursing support program designed for families of children aged 1 to 3 years who have undergone heart surgery.
- Conditions
- Congenital Heart Disease, Postoperative Care, Child Development, Roy Adaptation Model-based Nursing Empowerment Program
- Trial name
- NCT07575451
- Testing
- RAM-based Nursing Empowerment Program, Routine Care and Educational Booklet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Cystic Fibrosis, Pancreatic Insufficiency
Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)
Multicenter, explorative, phase IIIb, open-label study to assess the efficacy and safety of Ultrase® MT12, in the control of steatorrhea and clinical signs and symptoms of malabsorption in CF children with pancreatic…
- Trial name
- NCT00880100
- Testing
- Ultrase® MT12
- Where
- 15 sites in United States
- Volunteers
- 49 people
- Sponsor
- Forest Laboratories
Nutritional Stunting
Orange Almond Potato Cookies Supplementation
The goal of this clinical trial is to assess the effect of potato almond orange cookie supplementation on the nutritional status of stunted under-five children.
- Trial name
- CS (NCT05889819)
- Testing
- Almond orange potato cookies for stunted under-five children
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Meningitis
A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)
The main purpose of this study is to evaluate the immune response and safety of a booster dose of the meningococcal group B vaccine, rMenB+OMV NZ (also known as Bexsero), in adolescents and young adults aged 10 to 20 years.
- Trial name
- NCT06995430
- Testing
- rMenB+OMV NZ vaccine
- Where
- 17 sites in Finland, Italy and 2 more
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sevoflurane Anaesthesia
Effect of Animated Cartoon for Prevention of Emergence Agitation in Children Aged 1.5 - 5 yr After General Anesthesia
Emergence agitation (EA) in children early after sevoflurane anaesthesia is a common postoperative problem, with incidence ranging up to 80%.
- Trial name
- NCT01880138
- Testing
- watching animated cartoon before general anesthesia, not watching animated cartoon beofre general anaesthesia
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
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