Clinical trials: Girls
Herpes Simplex
Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old
Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04) vaccine group and the Saline control group throughout the study period (up to month 12).
- Trial name
- NCT00224484
- Testing
- GSK208141, Havrix (investigational formulation)
- Where
- 151 sites in United States, Australia and 16 more
- Volunteers
- 5,960 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pancreas Transplant, Type 1 Diabetes Mellitus
Pancreas Transplant Alone in Uremia and Non-uremia Patients
Theoretically, pancreas transplant alone in uremia (PTAu) or pancreas before kidney transplant (PBK) may be considered for patients awaiting both pancreas and kidney grafts, alongside options like simultaneous pancreas-kidney…
- Conditions
- Pancreas Transplant, Type 1 Diabetes Mellitus, Uremia
- Trial name
- PTAu (NCT07872800)
- Testing
- pancreas transplant
- Where
- Taiwan
- Volunteers
- 184 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Surgery, Pregnancy Complications
Evaluation of Practices at the University Hospital of Nancy in the Context of Surgery During Pregnancy
About 2% of pregnant women are going through from surgery during pregnancy. These are mainly represented by emergencies like abdominal conditions such as appendicitis.
- Conditions
- Surgery, Pregnancy Complications, Pregnancy Related
- Trial name
- NCT05759507
- Testing
- abdominal surgery
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Central Hospital, Nancy, France
Infants in NICU Ventilated With HFV
Capnography in Infants Ventilated With High Frequency Ventilation
The investigators hypothesize that dEtCO2 measured by the Microstream® technique via a double-lumen ETT in infants ventilated with HFV would be feasible and adequately represent the arterial CO2 (PaCO2).
- Trial name
- NCT00859209
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Bnai Zion Medical Center
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta
Database of Monochorionic Pregnancies
The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.
- Conditions
- Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Twin; Complicating Pregnancy, Twin to Twin Transfusion Syndrome
- Trial name
- NCT05543499
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Miami
Premature Infants, Gastroesophageal Reflux
Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER)
This study is crossover study to evaluate safety and efficacy of lansoprazole in preterm infants with gastroesophageal reflux.
- Trial name
- NCT01946971
- Testing
- Lansoprazole
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
Perinatal Depression
Early Detection of Perinatal Depression With Wearable Technology
The goal of this feasibility study is to learn whether wearable devices and self-report surveys can help researchers better understand changes in mood during pregnancy and after birth in young pregnant individuals with a history…
- Trial name
- BLUESMAPPED (NCT07784244)
- Testing
- Oura Ring (Photoplethysmography-based wearable ring), EmbracePlus Watch (Electrodermal activity wristband sensor)
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Preterms With Gestational Age Ranging From 30 to 35 Weeks
Evaluation of Safety, Tolerance and Effects on the Intestinal Flora of a New Fermented Milk for Preterm Infants
The intestinal flora is a complex ecosystem which is known to play various important functions in the gut. Recent data have reported a delay in intestinal colonization in preterm.
- Trial name
- NCT00711633
- Testing
- Milk with probiotic and prebiotic activities, Milk without probiotic and prebiotic activities
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome
The PCOS Challenge Study
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with…
- Trial name
- PCOSCHALLENGE (NCT05797909)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Diurnal Enuresis
Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction
Constipation treatment has been found to ameliorate symptoms in some patients with lower urinary tract dysfunction (including day time or combined day time/night time urinary incontinence).
- Trial name
- NCT02336906
- Testing
- polyethylene glycol 3350, Constipation behavioral therapy, Urotherapy
- Where
- Israel
- Sponsor
- Rabin Medical Center
Recurrent Miscarriages
Maternal KIR and Fetal HLA-C Genes in Recurrent Miscarriages
For implantation of developing conceptus, placental cells need to invade mother's uterus to access maternal blood supply in a control manner.
- Trial name
- NCT00180804
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Overweight/Obesity, Puberty
Improving Health Among Disadvantaged Girls to Slow Pubertal Onset and Reduce Long-term Health Risks
This study is testing whether improving health in girls during the prepubertal period may slow the onset of puberty. This study will focus on prepubertal girls who have a high weight status (at or above the 85th percentile for…
- Conditions
- Overweight/Obesity, Puberty, Health Behavior, Cardiometabolic Health
- Trial name
- NCT07460544
- Testing
- Family-Based Treatment (FBT)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Washington
Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
The purpose of this study is to analyze the gastric fluid aspirated from the stomachs of neonates receiving routine post-delivery care to predict the need for prolonged respiratory support (>6 hours of life).
- Conditions
- Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant, Transient Tachypnea of the Newborn, Meconium Aspiration Syndrome
- Trial name
- NCT07344714
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Urinary Retention, Rectal Cancer
Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2)
The objective of this trial is to investigate the effect of bladder training on the incidence of re-catheterization after proctectomy.
- Conditions
- Urinary Retention, Rectal Cancer, Urinary Catheterization
- Trial name
- NCT06217016
- Testing
- ICCAUT, Free drainage
- Where
- China
- Sponsor
- The First Hospital of Jilin University
brca1 Mutation Carrier, brca2 Mutation Carrier
Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as carboplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- brca1 Mutation Carrier, brca2 Mutation Carrier, Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
- Trial name
- NCT00321633
- Testing
- carboplatin, docetaxel
- Where
- 25 sites in Australia, Israel and 4 more
- Volunteers
- 148 people
- Sponsor
- University College London Hospitals
Dysphagia, Disorder; Feeding, Newborn
Effects of the Application of PIOMI in the Oral Feeding of Premature
The goal of this clinical trial is assess whether the application of the premature oral motor intervention (PIOMI) combined with the Newborn Individualized Developmental Care and Assessment Program (NIDCAP), allows withdrawal of…
- Conditions
- Dysphagia, Disorder; Feeding, Newborn, Premature
- Trial name
- PIOMI (NCT06395298)
- Testing
- Experimental group PIOMI, Control group NIDCAP
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Fundació Sant Joan de Déu
Cervical Intraepithelial Neoplasia
Retrospective Study on the Evolution of CIN 1 to 3 in Per and Postpartum in Nancy From 2014 to 2022
In France, the screening rate for cervical cancer remains too low. Screening is simple and non-invasive. Pregnant patients are most of the time young and are part of the target population for screening, and for many women, it is…
- Trial name
- NCT05595252
- Testing
- cervical biopsy
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Critical Illness, Acute Kidney Failure
Implementation of CRRT KPI Reports to Standardize and Improve the Quality of CRRT Delivery in Alberta "QUALITY CRRT"
Acute kidney replacement therapy (i.e., dialysis) is used in 6-10% of patients admitted to intensive care units (ICUs). The amount of acute kidney replacement therapy use has increased in Canadian ICUs over the last several…
- Trial name
- QUALITY-CRRT (NCT04221932)
- Testing
- CRRT KPI Reports
- Where
- 14 sites in Canada
- Volunteers
- 945 people
- Sponsor
- University of Alberta
Atherosclerosis, Cardiovascular Diseases
Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome
To investigate whether women with Polycystic Ovary syndrome (PCOS) have evidence of an increased prevalence rate of subclinical atherosclerosis as measured by the presence of plaque, increased intima-medial carotid artery wall…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases
- Trial name
- NCT00005459
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Prematurity
Early Intervention Based on Neonatal Crawling in Very Premature Infants Without Major Brain Damage
Extreme prematurity is constantly increasing according to the World Health Organization. However, methods to train premature infants at risk of disability is sorely lacking. The goal of this project is to overcome this problem.
- Trial name
- Premalocom1 (NCT05278286)
- Testing
- Crawling stimulation with the crawliskate, Tummy time without the crawliskate
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Marianne Barbu-Roth
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