Clinical trials: Glue Ear
Chronic Otitis Infections in pédiatric Patients
Efficacy of KNT® (KINETUBE) in Recurrent Chronic Otitis Media in Children
Otitis media are the consequence of bacterial infection. They are characterized by middle ear inflammations with a collection of fluid behind the eardrum.
- Trial name
- KINETUBE (NCT02038400)
- Testing
- KINETUBE medical Device, insertion of tympanic ventilation tubes (tympanostomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Otitis Media, Otitis Media Effusion
Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media
The goal of this clinical trial is to learn whether osteopathic manipulative treatment, or OMT, can reduce the need for tympanostomy tube surgery in children with recurrent or chronic otitis media who have been referred to an…
- Conditions
- Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children
- Trial name
- NCT07639775
- Testing
- Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sarah Vidal
Otitis Media With Effusion
Adenoidectomy for Otitis Media in 2-3 Year Old Children
The purpose of this study is to evaluate the efficacy of three different surgical treatments (1. Bilateral myringotomy and tube insertion (M\&T); 2. Adenoidectomy and bilateral myringotomy (A\&T); 3.
- Trial name
- NCT00016497
- Testing
- bilateral myringotomy, bilateral myringotomy and tubes, adenoidectomy
- Where
- United States
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Otitis Media With Effusion (OME), Otitis Media With Effusion in Children
Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion
Otitis media with effusion (OME) is a common condition in which fluid collects behind the eardrum without signs of infection. It can cause hearing problems and discomfort.
- Conditions
- Otitis Media With Effusion (OME), Otitis Media With Effusion in Children, Breathing Exercise
- Trial name
- NCT06967506
- Testing
- Blowing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Uşak University
Otitis Media With Effusion, Probiotics
Effect of Probiotics on Nasopharyngeal Microbiome of Children With Otitis Media With Effusion
The aim of this study is to investigate whether the microbiota in the upper respiratory tract (nasopharynx, adenoids and middle ear fluid) of otitis media with effusion (OME) patients is changed after 4 weeks of probiotic product…
- Conditions
- Otitis Media With Effusion, Probiotics, Adenoid Vegetations
- Trial name
- NCT03277820
- Testing
- Probactiol Mini
- Where
- Belgium
- Volunteers
- 37 people
- Sponsor
- University Hospital, Antwerp
Otitis Media With Effusion
The Effect of Osteopatic Cranial Techniques on the Audiometric and Tympanometric Values in Children Suffering From Otitis Media With Effusion.
Children with otitis media with effusion will be treated with osteopatic cranial techniques or with a placebo treatment. Before and after the treatment audiometric and tympanometric measures will take place.
- Trial name
- NCT00547326
- Testing
- treated with osteopatic cranial techniques
- Where
- Belgium
- Sponsor
- University Hospital, Ghent
OTITIS MEDIA WITH EFFUSION
Tympanostomy Tube Extrusion Time & Viscosity
Studies have focused on the factors that influence tympanostomy tube (TT) extrusion may contribute to the management of OME. In this study the investigators aimed to assess the correlation between the TT extrusion time and…
- Trial name
- NCT03848026
- Testing
- Middle ear fluid viscosity, Tympanostomy tube extrusion time
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Microplastics, Otitis Media With Effusion
Microplastics in Otitis Media With Effusion Material
Microplastic rate is increasing ib athmosphere. They can be found in lung, kidney, heart, even placenta. Otitis media with effusion (OME) is a clinical condition that is ver common in children.
- Conditions
- Microplastics, Otitis Media With Effusion, Biofilms
- Trial name
- NCT06316635
- Testing
- ventilation tube insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kerem Kökoğlu
Otitis Media With Effusion
Clinical Study of the Tympanostomy Tube Delivery System
The objective of this investigational study is to evaluate the safety and performance of the Acclarent Tympanostomy Tube Delivery System (TTDS) for the placement of the Tympanostomy Tube [TT(s)] in patients indicated for such…
- Trial name
- inVENT (NCT00939796)
- Testing
- Acclarent Tympanostomy Tube Delivery System
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media With Effusion
OTO-201 for the Treatment of Middle Ear Effusion in Pediatric Subjects Requiring Tympanostomy Tube Placement
The purpose of this study is to confirm the effectiveness, safety and tolerability of OTO-201 in the treatment of pediatric subjects with bilateral middle ear effusion who require tympanostomy tube placement.
- Trial name
- NCT01949155
- Testing
- OTO-201
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Otonomy, Inc.
Otitis Media, Otitis Media Chronic
SWIR Otoscopy Study
The aim of this study is to provide preliminary data to support future studies to demonstrate that the short wave infrared (SWIR) otoscope is a better diagnostic tool than a white light otoscope for diagnosing middle ear…
- Conditions
- Otitis Media, Otitis Media Chronic, Otitis Media Effusion
- Trial name
- NCT06944795
- Testing
- SWIR device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Otitis Media, Middle Ear Effusion
Middle Ear Disease Before Age 3, Treatment With Ear Tubes, and Literacy and Attentional Abilities at Ages 9 to 11
Middle-ear disease (infection and fluid) is the most common illness in young children after the common cold. Because hearing loss accompanies middle-ear disease, and because early life is a period of rapid development, concern…
- Trial name
- NCT00365092
- Testing
- Insertion of tympanostomy tubes
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Otorrhea, Otitis Media With Effusion in Children
Otiprio Versus Ciprodex Tympanostomy Tube Outcomes
Otolaryngologists routinely administer ear drops at the time of tympanostomy tube placement in order to prevent tube otorrhea; however, there is a lack of consensus as to which drops are the most effective, and whether a…
- Trial name
- NCT03347461
- Testing
- Otiprio, Ciprodex
- Where
- United States
- Sponsor
- Boston Medical Center
Otitis Media With Effusion
Study of the Expression of MMPs in OME in Children With Atrophy of the Eardrum
Metalloproteinases (MMPs) constitute a family of endopeptidases that cleaves the extracellular matrix as collagen included in the eardrum. Activity of MMP has been shown in some otitis media with effusion (OME) fluids.
- Trial name
- MMP and OME (NCT03611842)
- Testing
- preservation of mucosal otitis media
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Otitis Media With Effusion
Wideband Tympanometry in Otitis Media With Effusion
The investigators asked the question if they can better estimate the middle ear status in OME that help them to decide between early intervention or longer follow up.
- Trial name
- NCT04395261
- Testing
- Wideband Tympanometry
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Otitis Media Acute
Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children
A pragmatic, mixed-method trial is to show the ability of OtoSight to change management of the pediatric patient presenting with ear pain in a way that improves patient outcomes and reduces costs.
- Trial name
- OTO-MATIC (NCT06285812)
- Testing
- OtoSight Middle Ear Scope
- Where
- 7 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- PhotoniCare, Inc.
Otitis Media With Effusion
Secretory Otitis Media in Adenoids Hypertrophy Patients
This study aims to compare the fate of Secretory Otitis Media in patients with adenoids hypertrophy undergoing Adenoidectomy alone or with Myringotomy or with Myringotomy and Tympanostomy Tube application
- Trial name
- NCT04584073
- Testing
- Adenoidectomy alone or with Myringotomy or with Myringotomy and Tympanostomy Tube application
- Volunteers
- 150 people
- Sponsor
- Assiut University
Otitis Media, Otitis Media With Effusion
Study of Streptococcus Pneumoniae in Nose and Throats of Infants With Acute Otitis Media
The aim of this study is to assess in France the impact of Prevenar on the possible evolution of the pneumococcal serotypes distribution and antibiotic resistance in NP samples of children with AOM.
- Conditions
- Otitis Media, Otitis Media With Effusion, Pneumococcal Infections
- Trial name
- NCT00195611
- Testing
- Prevenar
- Where
- 35 sites in France
- Volunteers
- 3,293 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp