Clinical trials: Gluten Intolerance
Celiac Disease in Children, Nutritional Assessment
Assessment of Nutritional Status in Celiac Disease Using Muscle Ultrasound in Pediatric Patients.
The aim is to explain that celiac disease (CD) is an autoimmune, familial disease that develops in genetically predisposed individuals as a result of sensitivity to gluten found in grains and grain products, causing…
- Trial name
- NCT07885735
- Testing
- performing muscle ultrasonography on patients
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Celiac Disease
Treatment of Mild Enteropathy Celiac Disease
The main purpose of this study is to evaluate the natural history of gluten sensitivity in endomysial antibody positive adults with celiac disease suspicion, who were found to have a only mild enteropathy (Marsh I-II) in the…
- Trial name
- TMCD (NCT00628823)
- Testing
- Gluten-free diet
- Where
- Finland
- Volunteers
- 73 people
- Sponsor
- Tampere University Hospital
Celiac Disease, Irritable Bowel Syndrome
Irritable Bowel Syndrome Overlaping Celiac Disease
The goal of this prospective observational cohort stuty is to assess the prevalence of overlap irritable bowel syndrome on coeliac disease in patients on gluten-free diet.
- Conditions
- Celiac Disease, Irritable Bowel Syndrome, Overlap Syndrome
- Trial name
- IBSonCD (NCT05740306)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Centre of Postgraduate Medical Education
Patients With Coeliac Disease and Chronic Diarrhoea (>3 Loose/ Liquid Motions a Day for More Than 4 Weeks), Patients With Pancreatic Exocrine Insufficiency
Creon Use in Coeliac Patients With Low Faecal Pancreatic Elastase
Faecal elastase is an enzyme test used to identify the presence of pancreatic exocrine insufficiency. This condition manifests with symptoms of diarrhea, weight loss, causing potential impairment on an individual's quality of…
- Trial name
- NCT01865695
- Testing
- Creon
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hypothyroidism
Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharmaceutical Forms of L - Thyroxine in Patients With Primary Acquired Hypothyroidism
Thyroid disorders, in particular hypothyroidism, are associated with gastrointestinal impairment, such as celiac disease. A study reported an increased prevalence of celiac disease in a large cohort of children affected by…
- Trial name
- NCT02917863
- Testing
- L-Thyroxine (tablet, per os), L-Thyroxine (oral drops, solution)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Meyer Children's Hospital IRCCS
Celiac Disease in Children, Gluten Enteropathy
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
Celiac disease (CD) is an autoimmune gastrointestinal disease that is caused by intolerance to gluten in the diet. The mainstay of treatment is a gluten-free diet (GFD).
- Conditions
- Celiac Disease in Children, Gluten Enteropathy, Diet; Deficiency, Adherence, Treatment
- Trial name
- NCT06038344
- Testing
- Gluten-free food guide teaching
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Celiac Disease
Choosing a Preferred Serology Kit for Screening and Diagnosis of Celiac Disease
The investigators will perform prospective observational multicenter study which includes children with suspicion of CD who referred to gastroscopy and intestinal biopsies (study group) and children without suspicion of CD who…
- Trial name
- NCT02805816
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Rabin Medical Center
Celiac Disease
Serum Markers in Gluten Challenge
1. The purpose of this research study is to evaluate non-invasive markers of celiac disease activity in subjects that are on a gluten-free diet, in remission from celiac disease who undergo gluten challenge. 2.
- Trial name
- NCT00931892
- Testing
- Gluten
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Beth Israel Deaconess Medical Center
Celiac Disease
Response to Hepatitis B Vaccine in Celiac Disease Patients
Celiac disease and infection with hepatitis B virus (HBV) are very prevalent worldwide and carry a high morbidity rate. It has been recently shown that patients with celiac disease very often fail to develop immunity after…
- Trial name
- NCT00739128
- Testing
- hepatitis B vaccine (EngerixB)
- Where
- Israel
- Volunteers
- 210 people
- Sponsor
- Shaare Zedek Medical Center
Celiac Disease
Cytokine Profile in Children With Celiac Disease
Celiac disease (CD) is an immune-mediated systemic disease that is elicited by consumption of gluten and related prolamines in genetically susceptible individuals.
- Trial name
- NCT02244047
- Testing
- Bifidobacterium breve
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Celiac Disease, Celiac Disease in Children
Celiac Disease in Childhood-Adulthood Transition
Aims of this study are to evaluate adolescents with celiac disease during their transition from pediatrics to adult care, and to develop better healthcare follow-up practices.
- Conditions
- Celiac Disease, Celiac Disease in Children, Transition of Care, Follow-up
- Trial name
- CeliCAT (NCT05084937)
- Testing
- CeliCAT form
- Where
- 5 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Tampere University Hospital
Celiac Disease
Study of the NATURal History, Epidemiological, Clinical, Diagnostic and Therapeutic Aspects of CELiac Disease and Non-celiac Enteropathies
Celiac disease is a chronic immune-mediated enteropathy triggered by gluten intake, which affects the small intestine in genetically susceptible subjects (HLA-DQ2 and/or HLA-DQ8).
- Trial name
- NATURCEL (NCT07070596)
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital Mutua de Terrassa
Celiac Disease
AN-PEP on Gluten Exposure in Celiacs
The AN-PEP, an Aspergillus niger derived endopeptidase, has been developed aiming to produce a complete luminal detoxification of gluten.
- Trial name
- NCT04788797
- Testing
- Prolyl Endopeptidase
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Dr. C. Bonorino Udaondo Gastroenterology Hospital
Celiac Disease
INF-α Innate Immune Response to Gliadin
Background \& Aims The enteropathy in Celiac Disease (CD) is due the adaptive and to the innate immune response to gliadin peptides.
- Trial name
- NCT03221647
- Testing
- Intestinal biopsies
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- Federico II University
Celiac Disease
Prevalence of Renal Disease in Children With Celiac Disease
To assess the prevalence of renal disease in a pediatric population of patients with celiac disease by looking for the presence of hematuria and/or proteinuria.
- Trial name
- COELIGAN (NCT05049876)
- Testing
- urine sample taken during consultations
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Celiac Disease
Comparison of Engerix B Vaccine Versus Sci-B-Vac Vaccine in Celiac Patients
Celiac disease and infection with hepatitis B virus (HBV) are very prevalent worldwide and carry a high morbidity rate. It has been recently shown that patients with celiac disease very often fail to develop immunity after…
- Trial name
- NCT01159457
- Testing
- Hepatitis B vaccination (Sci-B-Vac), Hepatitis B vaccination (EngerixB)
- Where
- Israel
- Volunteers
- 210 people
- Sponsor
- Shaare Zedek Medical Center
Irritable Bowel Syndrome, Gluten Sensitivity
Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics.
Recently a new clinical entity, gluten sensitivity (GS), a form of gluten intolerance in which neither allergic nor autoimmune mechanisms can be identified, has been added to the spectrum of gluten-related disorders.
- Trial name
- GS-IBS (NCT02431585)
- Testing
- gluten
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Coeliac Disease
Interest of Urinary Measurement of Immunogenic Gluten Peptides (GIP) in the Follow-up of Pediatric Celiac Patients.
The main reason for insufficient control of celiac disease is non-adherence to the gluten-free diet (GFD), whether voluntary or involuntary. In children, involuntary exposures are common (canteens, snacks, restaurants).
- Trial name
- GIped (NCT07578038)
- Testing
- Urinary measurement of GIP, Usual follow-up and measurement of urinary GIP.
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Lenval
Coeliac Disease, Celiac Disease in Children
Supporting Children and Young People to Live Well With Coeliac Disease: A RCT
Managing a strict gluten-free diet is crucial for children and young people with coeliac disease. However, this can have adverse effects on psychological well-being and quality of life.
- Trial name
- NCT06930924
- Testing
- Parent self-help psychological resource
- Where
- United Kingdom
- Volunteers
- 350 people
- Sponsor
- University of Surrey
Celiac Disease in Children, Nutritional Deficiency
Celiac Disease and Quality of Life in Children and Adolescents (CeliaQLife)
Celiac disease is a disorder commonly diagnosed during childhood. The treatment is a lifelong gluten-free diet. Both the condition and the diet can influence the children's physical and emotional well-being.
- Conditions
- Celiac Disease in Children, Nutritional Deficiency, Quality of Life
- Trial name
- CeliaQLife (NCT06568263)
- Where
- 2 sites in Norway
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital