Clinical trials: Glymphatic System
Epilepsy, Cognitive Dysfunction
Cognitive Function and Glymphatic System in Children with Epilepsy
Epilepsy, one of the most common neurological disorders in childhood, is a chronic brain disease characterized by neurobiological, psychological and cognitive effects.
- Conditions
- Epilepsy, Cognitive Dysfunction, Seizure, Epileptic
- Trial name
- NCT06143241
- Testing
- Threshold IMT, Antiepileptic medication
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Neuroinflammation, Autism Spectrum Disorder
Imaging - Clinical Evaluation of Altered Nervous System Drainage
The current study aims to evaluate the aspects of perfusion, fluid diffusivity in the interstitium and the T1 and T2 signal of the PVS and WMH.
- Trial name
- I-CLEANED (NCT06432023)
- Testing
- Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Alzheimer, Alzheimer Dementia (AD)
Restoring Cervical Lymphatic Drainage in Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with the accumulation of abnormal proteins, including amyloid-beta and tau, in the brain.
- Trial name
- LymphDAD (NCT07854327)
- Testing
- Cervical lymphovenous anastomosis (LVA)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Siena
Glymphatic System, White Matter Disease
Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases
The dilation of perivascular spaces can be the result of various etiopathogenetic processes. White matter atrophy can cause enlargement of these perivascular spaces (PVS) but also obstruction of fluid drainage systems…
- Conditions
- Glymphatic System, White Matter Disease, Pediatric Disorder, Perivascular Disease
- Trial name
- NCT06335004
- Testing
- Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea