Clinical trials: Graft Complication
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Liver Failure, Kidney Failure
NIRS as a Continuous Noninvasive Monitoring System of Liver/Kidney Graft Perfusion
The aim of the investigators work is to describe the agreement between NIRS and ecodoppler, as monitoring systems of liver and kidney graft's perfusion in the immediate postoperative period in pediatric patients.
- Trial name
- NIRS (NCT02343016)
- Testing
- Near-InfraRed Spectroscopy (NIRS)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Mariella Enoc
Kidney Failure, Kidney Diseases
Study Evaluating Sirolimus in the Treatment of Kidney Transplant
The aim of this study is to test whether withdrawal of calcineurin inhibitors, followed by treatment with sirolimus, may improve renal function in renal transplant recipients with chronic allograft nephropathy.
- Trial name
- NCT00282217
- Testing
- Sirolimus
- Where
- 13 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Vascular Access Complication
Prosthetic Femoral Access for Haemodialysis
This study will compare the outcomes of tunneled femoral catheter and femoro-femoral arteriovenous graft as a bailout procedure for hemodialysis in chronic kidney disease patients with exhausted upper-extremity and chest-wall…
- Trial name
- NCT04746742
- Testing
- Tunneled Femoral Catheter (TFC) group, Femoro-femoral Arteriovenous graft (FF-AVG) group
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mansoura University
GVHD, Acute, Stem Cell Transplant Complications
Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)
The purpose of this study is to determine the efficacy and safety of combined Ruxolitinib With Corticosteroids as First Line Therapy for the severe acute GVHD (graft-versus-host disease )
- Trial name
- GVHD (NCT07509749)
- Testing
- Ruxolitinib and Methylprednisolone, Methylprednisolone
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Daihong Liu
GVHD, Acute Stem Cell Transplant Complications
MAP-guided Preemptive Therapy of aGvHD by Ruxolitinib
The goal of this observation study is to test in patients undergoing allogeneic hemopoietic stem-cell transplantation (allo-HSCT).
- Trial name
- NCT06075225
- Testing
- Ruxolitinib
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Sichuan University
Pseudoaneurysm
Pseudoaneurysm of the Greater Palatine Artery Following Autogenous Connective Tissue Gingival Graft : A Case Series
Gingival recession is defined as the apical migration of the gingival margin from the amelocemental junction. This condition may be associated with symptoms such as tooth hypersensitivity, root decay, and cosmetic complaints from…
- Trial name
- NCT03454490
- Testing
- Postoperative pseudoaneurysm of the greater palatine artery
- Volunteers
- 10 people
- Sponsor
- Hopital de l'Enfant-Jesus
Cleft Lip and Palate, Bone Graft; Complications
Correlation Between Body Mass Index and Progressive Grafted Bone in Cleft Patients
The cleft patients received alveolar bone graft(ABG) for alveolar defect. Body mass index (BMI) was measured for each patients when receiving ABG.
- Trial name
- NCT05002920
- Testing
- alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 39 people
- Sponsor
- Chang Gung Memorial Hospital
Nutrition Aspect of Cancer, Stem Cell Transplant Complications
Study on Intelligent Nutrition Support Therapy for Hematopoietic Stem Cell Transplantation Recipients
The use of high-dose radiotherapy, chemotherapy and preventive antibiotics in the preconditioning regimen before allogeneic hematopoietic stem cell transplantation can easily lead to damage to the gastrointestinal mucosa…
- Trial name
- NCT05590091
- Testing
- Parenteral nutrition;Enteral nutrition
- Volunteers
- 106 people
- Sponsor
- Hebei Yanda Ludaopei Hospital
Cancer
Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant
RATIONALE: Antithymocyte globulin, clofarabine, and rituximab may stop the patient's immune system from rejecting the donor's stem cells when they do not exactly match the patient's blood.
- Trial name
- NCT00617929
- Testing
- anti-thymocyte globulin, rituximab, clofarabine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postoperative Pain, Acute
Transversalis Fascia Plane Block for Iliac Bone Graft in Children
The purpose of this study is to determine which method is more effective in postoperative pain control in children undergoing iliac bone grafting for alveoloplasty under general anesthesia: ultrasound-guided transverse abdominal…
- Trial name
- NCT06403462
- Testing
- transversalis fascial plane block, transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Arteriovenous Graft, Arteriovenous Fistula
Validation of Arterio Venous Access Stage (AVAS) Classification
VAVASC trial is an observational multicentre study. The aim of this trial is to validate AVAS (arteriovenous vascular access stage) classification.
- Conditions
- Arteriovenous Graft, Arteriovenous Fistula, Dialysis Access Malfunction, Kidney Failure
- Trial name
- VAVASC (NCT04796558)
- Testing
- AVAS Classification
- Where
- Czechia
- Volunteers
- 800 people
- Sponsor
- Vascular surgery, University hospital Královské Vinohrady, Prague
Uropathy, Kidney Transplantation
Feasibility of Magnetic-end Double-J Ureteral Stent Use in Children
Double-J ureteral stent (DJUS) is one of the most common devices used in urology. Ureteral stenting has a wide spectrum of indications that can be summarized in two words: obstruction and leakage.
- Trial name
- EFUJA (NCT04384939)
- Testing
- magnetic-end Double-J ureteral stent
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deceased Donor Kidney Transplant, Acute Kidney Injury
Deceased Donor Biomarkers and Recipient Outcomes
Compared to chronic dialysis, kidney transplantation provides recipients with longer survival and better quality of life at a lower cost.
- Conditions
- Deceased Donor Kidney Transplant, Acute Kidney Injury, Delayed Graft Function, End Stage Renal Disease
- Trial name
- DDS (NCT01848249)
- Where
- 17 sites in United States
- Volunteers
- 1,679 people
- Sponsor
- Yale University
Kidney Transplant; Complications
Effects of Graft Vascular Dimensions on Surgical and Functional Outcomes of Living Donor Kidney Transplantation
1. Correlate the radiological and intraoperative measuring of the vascular dimensions, 2. Assess the effect of the vascular dimensions on the short-term surgical complications and 3.
- Trial name
- NCT05797389
- Volunteers
- 30 people
- Sponsor
- Assiut University
Malignant Hematological Diseases
Efficacy of Azithromycin to Prevent Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation
The occurrence of bronchiolitis obliterans syndrome (SBO) after allogeneic hematopoietic stem cell transplantation (HSCT) is considered to be a chronic pulmonary graft versus host disease (GVHD) that is associated with…
- Trial name
- ALLOZITHRO (NCT01959100)
- Testing
- Azithromycin
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stem Cell Transplant Complications
KIR Sequencing and Typing for Allograft in Nancy
The use of haploidentical donors for aHSCT has greatly increased this past decade leading to a major paradigm shift: while finding 10/10 HLA-matched donors represented the prior difficulty for decades, the current problem is…
- Trial name
- KIR-STAN (NCT04882605)
- Testing
- MHC typing, KIR typing, Assessment of KIR-based prediction scores
- Volunteers
- 156 people
- Sponsor
- Central Hospital, Nancy, France
Graft Failure, Stem Cell Transplant Complications
Modified Second Haplo-transplantation for Graft Failure
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. We previously reported encouraging results with a novel Flu/Cy regimen.
- Trial name
- NCT06512545
- Testing
- second allogeneic stem cell transplantation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Peking University People's Hospital