Clinical trials: Growth & Development
Autistic Disorder
Donepezil HCl & Cognitive Deficits in Autism
This 11-week study will examine the safety and effectiveness of the medication donepezil (Aricept®) compared to placebo for treating cognitive deficits in children and adolescents with Autism Spectrum Disorder.
- Trial name
- NCT00047697
- Testing
- Donepezil HCl
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children
Because oral probiotics reported to potentially induce endogenous Oxytocin, and Oxytocin has been reported to improve social behaviors, the investigators will conduct a pilot trial to compare the effects of probiotics and…
- Trial name
- NCT03337035
- Testing
- intranasal oxytocin, oral probiotics
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Child Development
Follow up of Long Term Neurodevelopmental Impact of the Type of Feeding During the First Year of Life at 10 Years Old
The Chilean infant Nutrition Trial was a prospective, randomized, double-blind, controlled study conducted in Santiago, Chile, between 2016 and The study aimed to evaluate growth and body composition changes between birth and two…
- Trial name
- NCT06917625
- Testing
- Imaging
- Where
- Chile
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Corporación de Apoyo de la Investigación Científica en Nutrición
Congenital Heart Disease, Tetralogy of Fallot
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development
The study team will use small pieces of human hearts which are removed as part of a required surgical procedure to study different objectives.
- Trial name
- NCT00243776
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Autistic Disorder, Constipation
Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
The clinical manifestation of autism spectrum disorder (ASD) is complex, with medical and mental health disruptions that occur with the three core behavioral criteria used for diagnosis (social behavior, communication, restricted…
- Conditions
- Autistic Disorder, Constipation, Gastrointestinal Diseases
- Trial name
- NCT02442115
- Testing
- Treatment of Functional Constipation by
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Psychological Distress
Mindfulness Training for Stress Management
This study will assess the short and long term effects of a group-based mindfulness programme (Mindfulness-Based Stress Reduction, MBSR) on first year medical and psychology students at the Universities of Oslo and Tromso.
- Trial name
- NCT00892138
- Testing
- Mindfulness training
- Where
- 2 sites in Norway
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Norwegian Knowledge Centre for the Health Services
Encopresis, Autistic Disorder
An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders
The purpose of this study is to try to treat bowel movement (BM) accidents differently with children with autism spectrum disorder (ASD). The study will use over-the-counter (OTC) medications to evoke predictable bowel movements.
- Trial name
- NCT02383758
- Testing
- Glycerin Suppository, Bisacodyl suppository, Senna
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Neoplasms Pancreatic
PRIMUS002: Looking at 2 Neo-adjuvant Treatment Regimens for Resectable and Borderline Resectable Pancreatic Cancer
PRIMUS 002 is looking at 2 different chemotherapy regimens in the neo-adjuvant setting for pancreatic cancer. Each treatment will be given for 3 months prior to surgery
- Trial name
- PRIMUS002 (NCT04176952)
- Testing
- FOLFOX-A, AG
- Where
- 3 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Judith Dixon-Hughes
Autistics Children
Efficiency of Bumetanide in Autistic Children
The purpose of this study is to determine if a treatment by bumetanide presents an efficiency at the level of the neuronal maturation in the autism
- Trial name
- BUMEA (NCT01078714)
- Testing
- bumetanide
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Malnutrition, Adolescent Development
Evaluating a Participatory Nutrition Education Model on Nutrition Literacy of Adolescent Girls in Rural Ghana.
Adolescent girls in the Upper Manya Krobo (UMK) district, Ghana are disproportionately burdened by ill-health in relation to their male counterparts.
- Conditions
- Malnutrition, Adolescent Development, Adolescent Behavior
- Trial name
- NCT03704649
- Testing
- Participatory video
- Where
- 2 sites in Canada, Ghana
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- McGill University
Autism Spectrum Disorder
Probiotics for Autism Spectrum Disorders: a Randomized Controlled Trial (The PASD Study)
Autism spectrum disorders (ASD) are a group of severe neurodevelopmental conditions characterized by impaired communication and social interaction, as well as repetitive/stereotyped behaviors deriving from a combination of…
- Trial name
- PASD (NCT07345585)
- Testing
- Lactobacillus rhamnosus GG
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder
The Effects of Yoga on Sensory, Motor, Cognitive Skills, and Perceived Stress in Children With Developmental Coordination Disorder
This clinical study aims to investigate the effects of yoga on children with Developmental Coordination Disorder (DCD). DCD is a condition that can make it difficult for children to perform everyday activities, as it affects…
- Conditions
- Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder, Sensory Integration Disorder, Perceived Stres Level
- Trial name
- NCT07547514
- Testing
- Yoga intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
COVID-19
Efficacy of a Multiplex BangasureTM RT-PCR Kit for the Detection of COVID-19
The outbreak of the severe acute respiratory syndrome (SARS) corona virus (CoV)-2 continues to increase globally. To control the coronavirus disease 2019 (COVID-19) transmission, diagnose is very important step which would help…
- Trial name
- COVID-19 (NCT05190016)
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- DR. MALA KHAN
Parkinson Disease
Development of Digital Diagnostic Devices for Parkinson's Disease
In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD.
- Trial name
- NCT06663826
- Testing
- oculomotor and pupillary function assessment
- Where
- Switzerland
- Volunteers
- 116 people
- Sponsor
- machineMD AG
Autism Spectrum Disorder, Parent
The Effect of Applied Group Training Given to Mothers With Children With Autism on Perceived Social Support, Depressive Symptoms and Self-compassion
Autism Spectrum Disorder (ASD), which can also be defined as a type of special need, is a congenital neurodevelopmental disorder whose symptoms are observed in early childhood.
- Trial name
- NCT06862804
- Testing
- practical group training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kastamonu University
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 6, who have been diagnosed with moderate to severe autism.
- Trial name
- TPBMASD (NCT04660552)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder, Disruptive Behavior
Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings
This study proposes to redesign the RUBI Parent Training program, a low-intensity intervention for youth with autism spectrum disorder and disruptive behavior, for use by school personnel in the classroom.
- Trial name
- NCT04199533
- Testing
- RUBI, RUBIES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism, Autism in Children
Developing a Novel Therapy for Aversive Sensory Experiences in Autism
The goal of this study is to assess whether a new psychological treatment can lead to changes in sensory experiences in autistic young people.
- Trial name
- NCT06682858
- Testing
- Group Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College London
Diarrhea, Diarrhea Infectious
A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa
This study aims to address the paucity of accurate incidence data of diarrheal diseases associated with Shigella in Zambia and Burkina Faso.
- Trial name
- ShigOraVax (NCT04312906)
- Testing
- no intervention
- Where
- 3 sites in Burkina Faso, Zambia
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Autism Spectrum Disorder
Diagnostic Performance of Exome Sequencing in Autism Spectrum Disorders
Evaluation of the diagnostic performance of exome sequencing in a prospective series of patients with autism spectrum disorders (ASD).
- Trial name
- REDIA (NCT04043351)
- Testing
- blood test
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Rouen
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